{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T15:00:11Z","timestamp":1769094011004,"version":"3.49.0"},"reference-count":20,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"5","license":[{"start":{"date-parts":[[2023,5,3]],"date-time":"2023-05-03T00:00:00Z","timestamp":1683072000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,5,3]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>This study aimed to investigate the differences in clinical features and routine peripheral blood testing between coronavirus disease 2019 (COVID-19) infection and influenza B infection. Patients with COVID-19 and influenza B admitted to our fever clinic from January 1, 2022 to June 30, 2022 were recruited. A total of 607 patients were included (301 with COVID-19 infection and 306 with influenza B infection). The results of a statistical analysis showed that 1) patients with COVID-19 infection were older and had a lower temperature and shorter duration from fever onset to clinic visit than patients with influenza B infection; 2) apart from fever, viral infection symptoms appeared to be more common in patients with influenza B infection than in patients with COVID-19 infection, including sore throat, cough, muscle aches, weeping, headache, fatigue, and diarrhea (<jats:italic>P<\/jats:italic> &lt; 0.001); and 3) compared with patients with influenza B infection, patients with COVID-19 infection had higher numbers of white blood cells and neutrophils but lower numbers of red blood cells and lymphocytes (<jats:italic>P<\/jats:italic> &lt; 0.001). In summary, several important differences were identified between COVID-19 and influenza B, which may help to guide clinicians in their initial diagnosis of these two respiratory viral infections.<\/jats:p>","DOI":"10.4269\/ajtmh.22-0620","type":"journal-article","created":{"date-parts":[[2023,3,13]],"date-time":"2023-03-13T12:33:42Z","timestamp":1678710822000},"page":"1028-1030","source":"Crossref","is-referenced-by-count":5,"title":["Comparison of Clinical Characteristics and Peripheral Blood Tests of COVID-19 and Influenza B Patients"],"prefix":"10.4269","volume":"108","author":[{"given":"Shan","family":"Yu","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases, Renji Hospital, Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China;"},{"name":"Shanghai University of Traditional Chinese Medicine, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"b1","series-title":"Infection","first-page":"233","article-title":"Epidemiology of SARS-CoV-2","volume":"49","author":"Bernd","year":"2021"},{"key":"b2","series-title":"Int J Infect Dis","first-page":"264","article-title":"The continuing 2019\u2013nCoV epidemic threat of novel coronaviruses to global health: the latest 2019 novel coronavirus outbreak in Wuhan, China","volume":"91","author":"Hui","year":"2020"},{"key":"b3","year":"2021"},{"key":"b4","year":"2021"},{"key":"b5","series-title":"Lancet","first-page":"497","article-title":"Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China","volume":"395","author":"Huang","year":"2020"},{"key":"b6","series-title":"Pathog Glob Health","first-page":"351","article-title":"Prevalence and genetic characterization of respiratory syncytial viruses circulating in Bulgaria during the 2014\/15 and 2015\/16 winter 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strategies: spatio-temporal modeling of surveillance data","volume":"10","author":"Yu","year":"2013"},{"key":"b12","series-title":"Chin Gen Pract","first-page":"14","article-title":"Epidemiologic features and containment of SARS-CoV-2 Omicron variant","volume":"25","author":"Wu","year":"2022"},{"key":"b13","series-title":"Zhongguo Yiyuan Ganranxue Zazhi","first-page":"3521","article-title":"Detection and distribution characteristics of flu viruses in 5447 cases of adult influenza-like illness during flu outbreaks","volume":"28","author":"Wu","year":"2018"},{"key":"b14","series-title":"J Southwest Jiaotong Univ (Social)","first-page":"71","article-title":"The impact of social support on mental health under the COVID-19 epidemic: the mediating role of emotion regulation strategies","volume":"23","author":"Liu","year":"2022"},{"key":"b15","series-title":"J Med Postgrad","first-page":"539","article-title":"Application of PCR in novel coronavirus nucleic acid detection","volume":"34","author":"Zhang","year":"2021"},{"key":"b16","series-title":"Epidemiol Infect","first-page":"199","article-title":"Influenza epidemiology and characterization of influenza viruses in patients seeking treatment for acute fever in Cambodia","volume":"138","author":"Blair","year":"2010"},{"key":"b17","year":"2021"},{"key":"b18","year":"2021"},{"key":"b19","series-title":"J Clin Exp Med","first-page":"969","article-title":"Analysis of blood cell characteristics and effect of oseltamivir phosphate on the treatment in patients with influenza A and B","volume":"19","author":"Sun","year":"2020"},{"key":"b20","series-title":"J Med Inf","first-page":"71","article-title":"Changes and clinical analysis of several infection indexes in children with influenza A and B","volume":"34","author":"Xie","year":"2021"}],"container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/108\/5\/article-p1028.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/108\/5\/article-p1028.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/108\/5\/article-p1028.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,3]],"date-time":"2023-05-03T19:42:32Z","timestamp":1683142952000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/108\/5\/article-p1028.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,3]]},"references-count":20,"journal-issue":{"issue":"5"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.22-0620","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5,3]]}}}