{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T05:32:54Z","timestamp":1787031174934,"version":"build-2736575974"},"reference-count":10,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,3,1]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n                  <jats:p>Mpox (formally monkeypox) is an Orthopoxvirus associated with both zoonotic and person-to-person spread. Human mpox classically presents with rash and systemic symptoms. Although sporadic outbreaks of mpox have occurred worldwide, the 2022 outbreak is the first of pandemic significance. Thousands of geographically dispersed cases were reported beginning in May 2022. The clinical presentations and outcomes of mpox infection have varied greatly based on viral clade. Further guidance is needed for clinicians to diagnose and treat this emerging infection. We present five clinical vignettes of confirmed cases diagnosed in June and July 2022 in northern California to demonstrate the range of mpox disease, including myocarditis, pharyngitis, epididymitis, and proctitis. We note a significant overlap with HIV infection and a high rate of concurrent sexually transmitted infection. Given the heterogenous presentations of mpox disease, clinicians should maintain a high degree of suspicion in patients with oropharyngeal or genital lesions, proctitis, or new rash.<\/jats:p>","DOI":"10.4269\/ajtmh.22-0626","type":"journal-article","created":{"date-parts":[[2023,1,30]],"date-time":"2023-01-30T09:23:16Z","timestamp":1675070596000},"page":"592-594","source":"Crossref","is-referenced-by-count":13,"title":["Case Report: Mpox \u2013 Not Just a Rash"],"prefix":"10.4269","volume":"108","author":[{"given":"Caitlin A.","family":"Contag","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine, Stanford University, Palo Alto, California;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abraar","family":"Karan","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine, Stanford University, Palo Alto, California;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucy","family":"Studemeister","sequence":"additional","affiliation":[{"name":"Santa Clara Valley Medical Center, Division of Infectious Diseases, AIDS Medicine, Mycobacterial Diseases, and International Health, San Jose, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajat","family":"Bansil","sequence":"additional","affiliation":[{"name":"Santa Clara Valley Medical Center, Division of Infectious Diseases, AIDS Medicine, Mycobacterial Diseases, and International Health, San Jose, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabel","family":"Fong","sequence":"additional","affiliation":[{"name":"Santa Clara Valley Medical Center, Division of Infectious Diseases, AIDS Medicine, Mycobacterial Diseases, and International Health, San Jose, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krithika","family":"Srinivasan","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine, Stanford University, Palo Alto, California;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge L.","family":"Salinas","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine, Stanford University, Palo Alto, California;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Supriya","family":"Narasimhan","sequence":"additional","affiliation":[{"name":"Santa Clara Valley Medical Center, Division of Infectious Diseases, AIDS Medicine, Mycobacterial Diseases, and International Health, San Jose, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph D.","family":"Cooper","sequence":"additional","affiliation":[{"name":"Santa Clara Valley Medical Center, Division of Infectious Diseases, AIDS Medicine, Mycobacterial Diseases, and International Health, San Jose, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harleen","family":"Sahni","sequence":"additional","affiliation":[{"name":"Santa Clara Valley Medical Center, Division of Infectious Diseases, AIDS Medicine, Mycobacterial Diseases, and International Health, San Jose, California"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"b1","year":"2022"},{"key":"b2","series-title":"N Engl J Med","first-page":"679","article-title":"Monkeypox virus infection in humans across 16 countries: April\u2013June 2022","volume":"387","author":"Thornhill","year":"2022"},{"key":"b3","series-title":"Emerg Infect Dis","first-page":"2508","article-title":"Myocarditis attributable to monkeypox virus infection in 2 patients, United States, 2022","volume":"28","author":"Rodriguez-Nava","year":"2022"},{"key":"b4","year":"2022"},{"key":"b5","series-title":"Eurosurveillance","first-page":"2200421","article-title":"Epidemiological, clinical and virological characteristics of four cases of monkeypox support transmission through sexual contact, Italy, May 2022","volume":"27","author":"Antinori","year":"2022"},{"key":"b6","series-title":"Eurosurveillance","first-page":"2200503","article-title":"Frequent detection of monkeypox virus DNA in saliva, semen, and other clinical samples from 12 patients, Barcelona, Spain, May to June 2022","volume":"27","author":"Peir\u00f3-Mestres","year":"2022"},{"key":"b7","series-title":"Clin Infect Dis","first-page":"145","article-title":"Myocarditis after smallpox vaccination: a case report","volume":"37","author":"Saurina","year":"2003"},{"key":"b8","series-title":"BMJ Case Rep","first-page":"2017223523","article-title":"Myocarditis secondary to smallpox vaccination","volume":"2018","author":"Keinath","year":"2018"},{"key":"b9","series-title":"Clin Infect Dis","first-page":"S242","article-title":"Myocarditis, pericarditis, and dilated cardiomyopathy after smallpox vaccination among civilians in the United States, January\u2013October 2003","volume":"46 (Suppl 3):","author":"Morgan","year":"2008"},{"key":"b10","year":"2022"}],"container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/108\/3\/article-p592.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/108\/3\/article-p592.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/108\/3\/article-p592.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T08:33:57Z","timestamp":1677659637000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/108\/3\/article-p592.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,1]]},"references-count":10,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.22-0626","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,3,1]]}}}