{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T02:57:28Z","timestamp":1785466648368,"version":"3.56.0"},"reference-count":30,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,4,5]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>Envenomation by scorpions belonging to the genus <jats:italic>Tityus<\/jats:italic> can be life threatening in the Americas, particularly in the Amazon Basin. We report a 4-month-old Ecuadorean boy of Shuar origin stung by a scorpion identified as <jats:italic>Tityus cisandinus<\/jats:italic> in the Amazonian province of Morona Santiago, presenting with pulmonary edema and systemic inflammation. We administered immunotherapy using the scorpion antivenom available in Ecuador, of Mexican origin (anti-<jats:italic>Centruroides<\/jats:italic>). Catecholamine discharge-related events such as hyperglycemia and thrombocytosis were resolved after treatment but leukocytosis did not, suggesting that factors associated with the sting-admission delay and specificity of antivenom played a role in the envenomation outcome. Cardiorespiratory arrest determined a fatal outcome, despite specific maneuvers. The case severity and the limited supply of nonspecific scorpion antivenoms in problematic areas of Amazonian Ecuador and elsewhere in northwestern Amazonia are discussed in regard to the need for specific therapeutic immunoglobulins in the area and in the Amazon Basin as a whole.<\/jats:p>","DOI":"10.4269\/ajtmh.22-0681","type":"journal-article","created":{"date-parts":[[2023,2,6]],"date-time":"2023-02-06T15:35:41Z","timestamp":1675697741000},"page":"807-810","source":"Crossref","is-referenced-by-count":6,"title":["Case Report: Fatal Scorpion Envenomation in a Shuar Child by Tityus cisandinus from Amazonian Ecuador: A Call for Specific Antivenom Availability in the Amazon Basin"],"prefix":"10.4269","volume":"108","author":[{"given":"Adolfo","family":"Borges","sequence":"first","affiliation":[{"name":"Centro para el Desarrollo de la Investigaci\u00f3n Cient\u00edfica, Asunci\u00f3n, Paraguay;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan P.","family":"Rom\u00e1n","sequence":"additional","affiliation":[{"name":"Hospital General de Macas, Macas, Ecuador"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"b1","series-title":"N Engl J Med","first-page":"457","article-title":"Scorpion envenomation","volume":"371","author":"Isbister","year":"2014"},{"key":"b2","series-title":"Drug Des Devel Ther","first-page":"165","article-title":"Emerging options for the management of scorpion stings","volume":"6","author":"Chippaux","year":"2012"},{"key":"b3","series-title":"Toxins (Basel)","first-page":"248","article-title":"The enzymatic core of scorpion venoms","volume":"14","author":"Delgado-Prudencio","year":"2022"},{"key":"b4","series-title":"Toxicon","first-page":"174","article-title":"Scorpion envenomation and inflammation: beyond neurotoxic effects","volume":"167","author":"Reis","year":"2019"},{"key":"b5","series-title":"Intensive Care Med","first-page":"401","article-title":"Scorpion 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