{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,6,17]],"date-time":"2024-06-17T10:29:59Z","timestamp":1718620199106},"reference-count":23,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,7,5]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>Leprosy is a chronic infection caused by <jats:italic>Mycobacterium leprae<\/jats:italic> and <jats:italic>Mycobacterium lepromatosis<\/jats:italic> that preferentially compromises peripheral nerve, skin, and mucous membranes. Colombia achieved the goal of leprosy elimination in 1997. However, in Urab\u00e1 (Colombia), there has been an increase in leprosy cases beginning in 2020. This case report shows a leprosy relapse 5 decades after the initial infection debuted as a necrotizing erythema nodosum leprosum. Therefore, long-term follow-up of patients with risk factors for relapse is emphasized, especially those treated before the standard of multidrug therapy (dapsone, clofazimine, and rifampin). This case report stresses the importance the importance of clinical follow-up and surveillance of patients with these events of interest for the public health.<\/jats:p>","DOI":"10.4269\/ajtmh.22-0701","type":"journal-article","created":{"date-parts":[[2023,5,30]],"date-time":"2023-05-30T15:16:43Z","timestamp":1685459803000},"page":"53-56","source":"Crossref","is-referenced-by-count":1,"title":["Case Report: Necrotizing Erythema Nodosum as a Manifestation of Lepromatous Leprosy Relapse 50 Years after the Initial Infection"],"prefix":"10.4269","volume":"109","author":[{"given":"Juan","family":"Galeano","sequence":"first","affiliation":[{"name":"University Hospital of M\u00fcnster, M\u00fcnster, Germany;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alejandra","family":"Contreras","sequence":"additional","affiliation":[{"name":"Rosario University, Bogot\u00e1, Colombia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lorena","family":"Pab\u00f3n","sequence":"additional","affiliation":[{"name":"Rosario University, Bogot\u00e1, Colombia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana C.","family":"Ruiz","sequence":"additional","affiliation":[{"name":"CES University, Medell\u00edn, Colombia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H\u00e9ctor","family":"Serrano-Coll","sequence":"additional","affiliation":[{"name":"Colombian Institute of Tropical Medicine ICMT-CES, Apartad\u00f3, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margarita","family":"Arboleda","sequence":"additional","affiliation":[{"name":"Colombian Institute of Tropical Medicine ICMT-CES, Apartad\u00f3, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"b1","series-title":"J Eur Acad Dermatol 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siglo XX","volume":"35","author":"Botero-Jaramillo","year":"2017"},{"key":"b18","series-title":"Chemotherapy of Leprosy for Control Programs: Report of a WHO Study Group\n World Health Organization Technical Report Series, No 675","year":"1982"},{"key":"b19","series-title":"Biom\u00e9dica","first-page":"133","article-title":"Recidivas postratamiento de la lepra multibacilar","volume":"24","author":"Rodr\u00edguez","year":"2004"},{"key":"b20","series-title":"Indian J Lepr","first-page":"45","article-title":"Clinical features and diagnosis of relapses in leprosy","volume":"67","author":"Ramu","year":"1995"},{"key":"b21","series-title":"Guidelines for the diagnosis, treatment, and prevention of leprosy","year":"2018"},{"key":"b22","series-title":"J Dtsch Dermatol Ges","first-page":"1133","article-title":"Atypical presentations of erythema nodosum leprosum: diagnostic and therapeutic aspects","volume":"19","author":"Alakad","year":"2021"},{"key":"b23","series-title":"Emerg Infect Dis","first-page":"1067","article-title":"Mycobacterium lepromatosis as Cause of Leprosy, Colombia","volume":"28","author":"Cardona-Castro","year":"2022"}],"container-title":["The American Journal of Tropical Medicine and 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