{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T05:55:19Z","timestamp":1791352519286,"version":"4.3.1"},"reference-count":21,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,10,4]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>The disease burden of arthropod-borne infections is particularly high in low- and middle-income countries, where the availability of resources for surveillance and testing is limited. The lack of local infrastructure demands that biological samples be sent to central laboratories by refrigerated transport, which increases costs and the risk of sample degradation. Dried blood spot samples are an alternative for ensuring sample integrity during transportation and storage. They can be used for the detection of nucleic acids and proteins, such as antigens or antibodies. Here, we compared anti-chikungunya IgM, anti-dengue IgM, anti-dengue IgG, and anti-Zika IgG detection between paired serum and dried serum samples (DSSs); the agreement between results was found to be 90.6%, 94.1%, 85.9%, and 95.5%, respectively, indicating a strong correlation. Our results suggest that DSSs provide a reliable alternative for detection of specific antibodies in arthropod-borne infections.<\/jats:p>","DOI":"10.4269\/ajtmh.22-0742","type":"journal-article","created":{"date-parts":[[2023,8,28]],"date-time":"2023-08-28T19:21:23Z","timestamp":1693250483000},"page":"933-936","source":"Crossref","is-referenced-by-count":5,"title":["Dried Serum Samples for Antibody Detection in Arthropod-Borne Virus Infections Are an Effective Alternative to Serum Samples"],"prefix":"10.4269","volume":"109","author":[{"given":"Daniela","family":"W\u00fcrsch","sequence":"first","affiliation":[{"name":"Unidad de Investigaci\u00f3n M\u00e9dica en Enfermedades Infecciosas y Parasitarias, Unidad M\u00e9dica de Alta Especialidad Hospital de Pediatr\u00eda, Centro M\u00e9dico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico;"},{"name":"Programa de Doctorado en Ciencias Biom\u00e9dicas, Universidad Nacional Aut\u00f3noma de M\u00e9xico, Mexico City, Mexico;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Othon","family":"Rojas-Montes","sequence":"additional","affiliation":[{"name":"Unidad de Investigaci\u00f3n M\u00e9dica en Enfermedades Infecciosas y Parasitarias, Unidad M\u00e9dica de Alta Especialidad Hospital de Pediatr\u00eda, Centro M\u00e9dico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ang\u00e9lica","family":"Maldonado-Rodr\u00edguez","sequence":"additional","affiliation":[{"name":"Unidad de Investigaci\u00f3n M\u00e9dica en Enfermedades Infecciosas y Parasitarias, Unidad M\u00e9dica de Alta Especialidad Hospital de Pediatr\u00eda, Centro M\u00e9dico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edgar","family":"Sevilla-Reyes","sequence":"additional","affiliation":[{"name":"Laboratorio de Transcript\u00f3mica e Inmunolog\u00eda Molecular, Instituto Nacional de Enfermedades Respiratorias Ismael Cos\u00edo Villegas, Ciudad de Mexico, Mexico;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Mar\u00eda","family":"Cevallos","sequence":"additional","affiliation":[{"name":"Departamento de Biolog\u00eda Molecular y Biotecnolog\u00eda, Instituto de Investigaciones Biom\u00e9dicas, Universidad Nacional Aut\u00f3noma de M\u00e9xico, Ciudad Universitaria, Mexico City, Mexico;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilma","family":"S\u00e1nchez-Burgos","sequence":"additional","affiliation":[{"name":"Unidad de Investigaci\u00f3n M\u00e9dica Yucat\u00e1n, Instituto Mexicano del Seguro Social, M\u00e9rida, Mexico;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adolfo","family":"Ch\u00e1vez-Negrete","sequence":"additional","affiliation":[{"name":"Educaci\u00f3n e Investigaci\u00f3n en Salud, Unidad M\u00e9dica de Alta Especialidad Hospital de Especialidades, Centro M\u00e9dico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosal\u00eda","family":"Lira","sequence":"additional","affiliation":[{"name":"Unidad de Investigaci\u00f3n M\u00e9dica en Enfermedades Infecciosas y Parasitarias, Unidad M\u00e9dica de Alta Especialidad Hospital de Pediatr\u00eda, Centro M\u00e9dico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"b1","series-title":"Int J Virol AIDS","first-page":"067","article-title":"Emerging and re-Emerging viral diseases: the case of coronavirus disease-19 (COVID-19)","volume":"7","author":"Abebe","year":"2020"},{"key":"b2","series-title":"Nat Microbiol","first-page":"796","article-title":"The continued threat of emerging flaviviruses","volume":"5","author":"Pierson","year":"2020"},{"key":"b3","series-title":"Acta Trop","first-page":"47","article-title":"Low socioeconomic condition and the risk of dengue fever: a direct relationship","volume":"180","author":"Farinelli","year":"2018"},{"key":"b4","year":"2020"},{"key":"b5","series-title":"Annu Rev Med","first-page":"395","article-title":"Zika, chikungunya, and other emerging vector-borne viral diseases","volume":"69","author":"Weaver","year":"2018"},{"key":"b6","series-title":"Acta Trop","first-page":"99","article-title":"Molecular epidemiology of dengue, yellow fever, Zika and chikungunya arboviruses: an update","volume":"190","author":"Higuera","year":"2019"},{"key":"b7","series-title":"J Immunol Methods","first-page":"113019","article-title":"Dried blood spots for the quantitative evaluation of IgG isotypes and correlation with serum samples in HIV-exposed uninfected (HEU) 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Dis","first-page":"13","article-title":"Enzyme-linked immunoassay for dengue virus IgM and IgG antibodies in serum and filter paper blood","volume":"6","author":"Tran","year":"2006"}],"container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/109\/4\/article-p933.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/109\/4\/article-p933.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/109\/4\/article-p933.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,4]],"date-time":"2023-10-04T12:50:38Z","timestamp":1696423838000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/109\/4\/article-p933.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,4]]},"references-count":21,"journal-issue":{"issue":"4"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.22-0742","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10,4]]}}}