{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,27]],"date-time":"2024-08-27T23:34:44Z","timestamp":1724801684273},"reference-count":20,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,5,3]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>Although local transmission of malaria has been eliminated, the disease is frequently imported to China by Chinese travelers returning from Africa. Optic neuritis (ON) is occasionally reported in malarial cases and usually shows good visual recovery and prognosis. Herein, we report severe visual loss with poor recovery due to bilateral ON in a malarial patient who traveled from Nigeria. While he was still in Nigeria, his visual acuity dropped to no light perception in both eyes after the third episode of malaria, which was confirmed by a positive blood smear for malarial parasites. His general condition gradually improved after a 6-day course of artesunate therapy. However, visual acuity in both eyes remained unchanged after artesunate therapy alone, with gradual improvement subsequently shown after pulse steroid therapy. Our case indicates that early antimalarial drugs combined with pulse steroid therapy may be of great importance for good visual recovery in ON cases after malarial infection.<\/jats:p>","DOI":"10.4269\/ajtmh.22-0797","type":"journal-article","created":{"date-parts":[[2023,3,27]],"date-time":"2023-03-27T12:52:57Z","timestamp":1679921577000},"page":"868-870","source":"Crossref","is-referenced-by-count":2,"title":["Case Report: Severe Optic Neuritis after Multiple Episodes of Malaria in a Traveler to Africa"],"prefix":"10.4269","volume":"108","author":[{"given":"Chuan-bin","family":"Sun","sequence":"first","affiliation":[{"name":"Eye Center, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhiqiong","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Xiaoshan Hospital, Hangzhou, China;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhe","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Zhejiang Provincial People\u2019s Hospital, People\u2019s Hospital of Hangzhou Medical College, Hangzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"b1","series-title":"Continuum (Minneap Minn)","first-page":"1422","article-title":"Infectious optic neuropathies","volume":"25","author":"Eggenberger","year":"2019"},{"key":"b2","series-title":"Eye Brain","first-page":"59","article-title":"Infectious optic neuropathies: a clinical update","volume":"7","author":"Kahloun","year":"2015"},{"key":"b3","series-title":"Surv Ophthalmol","first-page":"161","article-title":"Ocular parasitoses: a comprehensive review","volume":"62","author":"Padhi","year":"2017"},{"key":"b4","series-title":"J Neurol Sci","first-page":"117287","article-title":"Environmental neurology in the 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Bao","first-page":"327","article-title":"Etiology and ophthalmic characteristics of infectious and infection-related optic neuropathies","volume":"35","author":"Sun","year":"2020"},{"key":"b20","series-title":"Chin J Ocul Fundus Dis.","first-page":"955","article-title":"Chinese expert consensus on the diagnosis and treatment of infiltrative optic neuropathy (2022) [in Chinese]","volume":"38","year":"2022"}],"container-title":["The American Journal of Tropical Medicine and 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