{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,12,7]],"date-time":"2023-12-07T00:44:06Z","timestamp":1701909846560},"reference-count":24,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,12,6]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>The clinical manifestations of leptospirosis range from mild to life-threatening and can impact on multiple organ systems. A wide array of neurological manifestations of leptospirosis have been reported, although the pathophysiology of neuroleptospirosis remains incompletely understood. We present a case of leptospirosis complicated by bilateral sensorineural deafness, with nodular meningitis demonstrated in the internal auditory meatus on magnetic resonance imaging. The patient was treated with doxycycline, ceftriaxone, systemic and topical steroids, and hyperbaric oxygen therapy, with modest, but incomplete, improvement.<\/jats:p>","DOI":"10.4269\/ajtmh.23-0100","type":"journal-article","created":{"date-parts":[[2023,10,9]],"date-time":"2023-10-09T20:18:09Z","timestamp":1696882689000},"page":"1238-1241","source":"Crossref","is-referenced-by-count":0,"title":["Case Report: Leptospirosis Complicated by Persistent, Bilateral Sensorineural Hearing Loss"],"prefix":"10.4269","volume":"109","author":[{"given":"Stuart","family":"Campbell","sequence":"first","affiliation":[{"name":"Division of Medicine, Cairns Hospital, Cairns, Australia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James","family":"Stewart","sequence":"additional","affiliation":[{"name":"Division of Medicine, Cairns Hospital, Cairns, Australia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gavin","family":"Quail","sequence":"additional","affiliation":[{"name":"Department of Surgery, Cairns Hospital, Cairns, Australia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Grant","family":"Withey","sequence":"additional","affiliation":[{"name":"Department of Radiology, Cairns Hospital, Cairns, Australia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon","family":"Smith","sequence":"additional","affiliation":[{"name":"Division of Medicine, Cairns Hospital, Cairns, Australia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josh","family":"Hanson","sequence":"additional","affiliation":[{"name":"Division of Medicine, Cairns Hospital, Cairns, Australia;"},{"name":"The Kirby Institute, University of New South Wales, Sydney, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"b1","series-title":"PLoS Negl Trop Dis","first-page":"e0003898","article-title":"Global morbidity and mortality of leptospirosis: a systematic review","volume":"9","author":"Costa","year":"2015"},{"key":"b2","series-title":"PLoS Negl Trop Dis","first-page":"e0007205","article-title":"A simple score to predict severe leptospirosis","volume":"13","author":"Smith","year":"2019"},{"key":"b3","series-title":"PLoS Negl Trop Dis","first-page":"e0007929","article-title":"Severe leptospirosis in tropical Australia: optimising intensive care unit management to reduce mortality","volume":"13","author":"Smith","year":"2019"},{"key":"b4","series-title":"Indian J Med Res","first-page":"155","article-title":"Neuroleptospirosis \u2013 revisited: experience from a tertiary care neurological centre from south India","volume":"124","author":"Mathew","year":"2006"},{"key":"b5","series-title":"Postgrad Med J","first-page":"589","article-title":"Primary neuroleptospirosis","volume":"77","author":"Panicker","year":"2001"},{"key":"b6","series-title":"PLOS Glob Public Health","first-page":"e0000506","article-title":"The seasonality of infections in tropical Far North Queensland, Australia: a 21-year retrospective evaluation of the seasonal patterns of six endemic pathogens","volume":"2","author":"Fairhead","year":"2022"},{"key":"b7","series-title":"PLoS One","first-page":"e0265410","article-title":"The epidemiology and outcomes of central nervous system infections in Far North Queensland, tropical Australia; 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