{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T14:25:22Z","timestamp":1773411922039,"version":"3.50.1"},"reference-count":20,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"4","license":[{"start":{"date-parts":[[2023,10,4]],"date-time":"2023-10-04T00:00:00Z","timestamp":1696377600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,10,4]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>Mass drug administration (MDA) is a key strategy for the control of soil-transmitted helminths (STHs). Within MDA programs, poor and non-random compliance threaten successful control of STHs. A case-control study was conducted comparing perceptions among non-compliant participants with compliant participants during a community-wide MDA (cMDA) with albendazole in southern India. Common reasons cited for non-compliance were that the individual was not infected with STH (97.4%), the perception that he\/she was healthy (91%), fear of side-effects (12.8%), and dislike of consuming tablets (10.3%). Noncompliance was associated with poor awareness of intestinal worms (odds ratio [OR]: 9.63, 95% CI: 2.11\u201343.84), the perception that cMDA was only required for those with worms (OR: 2.14, 95% CI: 1.06\u20134.36), and the perception that the drug is not safe during pregnancy (OR: 2.19, 95% CI: 1.18\u20134.07) or when on concomitant medications (OR: 3.14, 95% CI: 1.38\u20137.15). Understanding of perceptions driving noncompliance can provide valuable insights to optimize participation during MDA for STHs.<\/jats:p>","DOI":"10.4269\/ajtmh.23-0176","type":"journal-article","created":{"date-parts":[[2023,8,21]],"date-time":"2023-08-21T14:57:30Z","timestamp":1692629850000},"page":"830-834","source":"Crossref","is-referenced-by-count":2,"title":["Perceptions Associated with Noncompliance to Community-Wide Mass Drug Administration for Soil-Transmitted Helminths"],"prefix":"10.4269","volume":"109","author":[{"given":"Kulandaipalayam Natarajan","family":"Sindhu","sequence":"first","affiliation":[{"name":"The Wellcome Trust Research Laboratory, Division of Gastrointestinal Sciences, Christian Medical College, Vellore, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kumudha","family":"Aruldas","sequence":"additional","affiliation":[{"name":"The Wellcome Trust Research Laboratory, Division of Gastrointestinal Sciences, Christian Medical College, Vellore, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saravanakumar Puthupalayam","family":"Kaliappan","sequence":"additional","affiliation":[{"name":"The Wellcome Trust Research Laboratory, Division of Gastrointestinal Sciences, Christian Medical College, Vellore, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elavarasan","family":"Mahendran","sequence":"additional","affiliation":[{"name":"The Wellcome Trust Research Laboratory, Division of Gastrointestinal Sciences, Christian Medical College, Vellore, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judd L.","family":"Walson","sequence":"additional","affiliation":[{"name":"Department of Global Health, University of Washington, Seattle, Washington;"},{"name":"Department of Medicine, University of Washington, Seattle, Washington;"},{"name":"Department of Pediatrics, University of Washington, Seattle, Washington;"},{"name":"Department of Epidemiology, University of Washington, Seattle, Washington;"},{"name":"The DeWorm3 Project, University of Washington, Seattle, Washington"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arianna Rubin","family":"Means","sequence":"additional","affiliation":[{"name":"Department of Global Health, University of Washington, Seattle, Washington;"},{"name":"The DeWorm3 Project, University of Washington, Seattle, Washington"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sitara Swarna Rao","family":"Ajjampur","sequence":"additional","affiliation":[{"name":"The Wellcome Trust Research Laboratory, Division of Gastrointestinal Sciences, Christian Medical College, Vellore, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"b1","year":"2018"},{"key":"b2","series-title":"Trans R Soc Trop Med Hyg","first-page":"538","article-title":"Coverage of, and compliance with, mass drug administration under the programme to eliminate lymphatic 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community: results from the DeWorm3 Trial in southern India","volume":"15","author":"Ajjampur","year":"2012"},{"key":"b14","series-title":"Glob Health Action","first-page":"1785146","article-title":"Development and application of an electronic treatment register: a system for enumerating populations and monitoring treatment during mass drug administration","volume":"13","author":"Oswald","year":"2020"},{"key":"b15","series-title":"Glob Health Res Policy","first-page":"1","article-title":"Policy stakeholder perspectives on barriers and facilitators to launching a community-wide mass drug administration program for soil-transmitted helminths","volume":"7","author":"Roll","year":"2022"},{"key":"b16","series-title":"Am J Trop Med Hyg","first-page":"260","article-title":"Knowledge and practice related to compliance with mass drug administration during the Egyptian National Filariasis Elimination Program","volume":"89","author":"Abd Elaziz","year":"2013"},{"key":"b17","series-title":"Infect 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