{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T04:24:37Z","timestamp":1772771077147,"version":"3.50.1"},"reference-count":15,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,4,3]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>Pregnant women and women of childbearing age were enrolled in our study and their knowledge about the Hepatitis B virus (HBV) and chronic hepatitis B (CHB) was evaluated. A questionnaire was distributed to every woman in the cross-sectional study. The questionnaire was answered by all participants before they received health education and advice about HBV and CHB from the doctors visited. Data collected from all answers were analyzed using the \u03c7<jats:sup>2<\/jats:sup> test and logistic regression models. A total of 206 pregnant women and women of childbearing age with CHB infection were enrolled in the study during their first visit to the Infectious Diseases Clinic of the Third Affiliated Hospital of Guangzhou Medical University. Some women of childbearing age (40.8%) and pregnant women with CHB infection (30.6%) still believed HBV could be transmitted through diet and\/or mosquito bites. Some women of childbearing age and pregnant women with CHB infection had limited knowledge of the prevention of HBV transmission (111 of 206, 53.9%). Women with higher levels of education had more knowledge about HBV (senior middle school, <jats:italic>P<\/jats:italic> = 0.02; university, <jats:italic>P<\/jats:italic> &lt;0.01). The majority of participants were willing to take antiviral medicine to decrease the mother-to-child transmission (MTCT) rate of HBV. Some women of childbearing age and\/or pregnant women with CHB infection have relatively limited knowledge about HBV or CHB. This situation contributes to the timeliness, or lack thereof, of these women with CHB to see a doctor and receive antiviral therapy. As a result, the morbidity and mortality of HBV-related complications could increase along with the rate of MTCT of HBV.<\/jats:p>","DOI":"10.4269\/ajtmh.23-0217","type":"journal-article","created":{"date-parts":[[2024,3,5]],"date-time":"2024-03-05T19:29:04Z","timestamp":1709666944000},"page":"719-723","source":"Crossref","is-referenced-by-count":2,"title":["Chronic Hepatitis B in Women of Childbearing Age and Pregnant Women in China: A Cross-Sectional Study"],"prefix":"10.4269","volume":"110","author":[{"given":"Liyang","family":"Zhou","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases, Guangdong Provincial Key Laboratory of Major Obstetric Diseases, and Guangdong Provincial Clinical Research Center for Obstetrics and Gynecology, Third Affiliated Hospital, Guangzhou Medical University, Guangzhou, China;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xitao","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Clinical Research Management Office, Third Affiliated Hospital, Guangzhou Medical University, Guangzhou, China;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xueting","family":"Ou","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Guangdong Provincial Key Laboratory of Major Obstetric Diseases, and Guangdong Provincial Clinical Research Center for Obstetrics and Gynecology, Third Affiliated Hospital, Guangzhou Medical University, Guangzhou, China;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiongyu","family":"Sheng","sequence":"additional","affiliation":[{"name":"Department of Clinical Research Management Office, Third Affiliated Hospital, Guangzhou Medical University, Guangzhou, China;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bing","family":"Situ","sequence":"additional","affiliation":[{"name":"Department of Clinical Research Management Office, Third Affiliated Hospital, Guangzhou Medical University, Guangzhou, China;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fang","family":"He","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Third Affiliated Hospital, Guangzhou Medical University, Guangzhou, China;"},{"name":"Guangzhou Obstetrics Critical Care Center, Key Laboratory for Major Obstetric Diseases of Guangdong Province, Guangzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xingfei","family":"Pan","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Guangdong Provincial Key Laboratory of Major Obstetric Diseases, and Guangdong Provincial Clinical Research Center for Obstetrics and Gynecology, Third Affiliated Hospital, Guangzhou Medical University, Guangzhou, China;"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"b1","series-title":"Nat Rev Dis Primers","first-page":"18036","article-title":"Hepatitis B virus infection","volume":"4","author":"Yuen","year":"2018"},{"key":"b2","series-title":"J Hepatol","first-page":"370","article-title":"EASL 2017 clinical practice guidelines on the management of hepatitis B virus infection","volume":"67","year":"2017"},{"key":"b3","series-title":"Aliment Pharmacol Ther","first-page":"5","article-title":"Review article: the prevention of hepatitis B-related hepatocellular carcinoma","volume":"48","author":"Lin","year":"2018"},{"key":"b4","series-title":"Best Pract Res Clin Obstet Gynaecol","first-page":"78","article-title":"Hepatitis B: vertical transmission and the prevention of mother-to-child transmission","volume":"68","author":"Cheung","year":"2020"},{"key":"b5","series-title":"N Engl J Med","first-page":"2324","article-title":"Tenofovir to prevent hepatitis B transmission in mothers with high viral load","volume":"374","author":"Pan","year":"2016"},{"key":"b6","series-title":"J Infect","first-page":"146","article-title":"Clinical course and perinatal transmission of chronic hepatitis B during pregnancy: a real-world prospective cohort study","volume":"75","author":"Chen","year":"2017"},{"key":"b7","series-title":"Sci Rep","first-page":"13631","article-title":"Efficacy and safety of continuous antiviral therapy from preconception to prevent perinatal transmission of hepatitis B virus","volume":"10","author":"Pan","year":"2020"},{"key":"b8","series-title":"J Viral Hepat","first-page":"1052","article-title":"Racial\/ethnic disparities in the prevalence and awareness of Hepatitis B virus infection and immunity in the United States","volume":"24","author":"Kim","year":"2017"},{"key":"b9","series-title":"J Infect Dev Ctries","first-page":"391","article-title":"A knowledge survey of obstetrics and gynecology staff on the prevention of mother-to-child transmission of Hepatitis B virus","volume":"7","author":"Hu","year":"2013"},{"key":"b10","series-title":"BMC Public Health","first-page":"537","article-title":"Mother-to-child transmission of hepatitis B: extent of knowledge of physicians and midwives in Eastern region of Ghana","volume":"16","author":"Adjei","year":"2016"},{"key":"b11","series-title":"PLoS One","first-page":"e0178671","article-title":"Knowledge of and attitudes towards hepatitis B and its transmission from mother to child among pregnant women in Guangdong Province, China","volume":"12","author":"Han","year":"2017"},{"key":"b12","series-title":"Ter Arkh","first-page":"4","article-title":"Chronic hepatitis B and C as stigma: is the problem relevant for Russian society?]","volume":"91","author":"Baramzina","year":"2019"},{"key":"b13","series-title":"Trop Gastroenterol","first-page":"180","article-title":"Attitudes towards maternal screening for Hepatitis B virus infection in Iran","volume":"31","author":"Adibi","year":"2010"},{"key":"b14","series-title":"Open Forum Infect Dis","first-page":"ofv122","article-title":"A survey study of pregnant women and healthcare practitioners assessing the knowledge of attitudes and practices of hepatitis b management at a teaching hospital in Kumasi, Ghana, West Africa","volume":"2","author":"Cheng","year":"2015"},{"key":"b15","series-title":"JAMA","first-page":"1075","article-title":"Altered reactivity to measles virus: atypical measles in children previously immunized with inactivated measles virus vaccines","volume":"202","author":"Fulginiti","year":"1967"}],"container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/110\/4\/article-p719.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/110\/4\/article-p719.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/110\/4\/article-p719.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,3]],"date-time":"2024-04-03T13:06:48Z","timestamp":1712149608000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/110\/4\/article-p719.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,3]]},"references-count":15,"journal-issue":{"issue":"4"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.23-0217","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,3]]}}}