{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T07:45:17Z","timestamp":1771919117649,"version":"3.50.1"},"reference-count":12,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"3","license":[{"start":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T00:00:00Z","timestamp":1693958400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,9,6]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>Hepatic alveolar echinococcosis (AE) is a zoonotic disease caused by the metacestode of <jats:italic>Echinococcus multilocularis<\/jats:italic>. Although surgical resection is the optimal treatment for hepatic AE, some patients with hepatic AE located in special introhepatic sites cannot be radically cured by conventional surgery. Here, we report that a 10-year-old female patient was admitted to the hospital with occupying liver lesions for 6 months. Computed tomography examination showed irregular mixed-density masses in the right lobe and caudate lobe of the liver, with partial invasion of the right hepatic artery, right hepatic vein, and right branch of the portal vein. The patient was preoperatively diagnosed with hepatic AE, which cannot be cured by conventional liver lobectomy. The patient underwent semi-ex vivo liver resection with autologous liver transplantation (second hepatic portal reconstruction, posterior hepatic inferior vena cava repair, and hepatic artery repair) and biliary-intestinal anastomosis. After hospital discharge, she has kept living a healthy life without disease recurrence for 13 months until the end of the last follow-up. This case shows that semi-ex vivo hepatectomy with autologous liver transplantation might be a feasible and safe choice for certain patients with AE located in special introhepatic sites, which has provided novel experiences for the surgical treatment of hepatic AE.<\/jats:p>","DOI":"10.4269\/ajtmh.23-0276","type":"journal-article","created":{"date-parts":[[2023,8,7]],"date-time":"2023-08-07T14:52:47Z","timestamp":1691419967000},"page":"640-644","source":"Crossref","is-referenced-by-count":4,"title":["Case Report: Semi-Ex Vivo Hepatectomy Combined with Autologous Liver Transplantation for Alveolar Echinococcosis in Children"],"prefix":"10.4269","volume":"109","author":[{"given":"Pan","family":"Xia","sequence":"first","affiliation":[{"name":"Department of Graduate School, Qinghai University, Xining, China;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiang-Qian","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Qinghai Provincial People\u2019s Hospital, Xining, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qing-Shan","family":"Tian","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Qinghai Provincial People\u2019s Hospital, Xining, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chao-Liang","family":"Shang-Guan","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Qinghai Provincial People\u2019s Hospital, Xining, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hai-Hong","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Qinghai Provincial People\u2019s Hospital, Xining, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"b1","series-title":"Adv Parasitol","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/bs.apar.2016.11.001","article-title":"Global distribution of alveolar and cystic echinococcosis","volume":"95","author":"Deplazes","year":"2017"},{"key":"b2","series-title":"Adv Parasitol","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/bs.apar.2019.03.001","article-title":"Echinococcosis transmission on the Tibetan Plateau","volume":"104","author":"Craig","year":"2019"},{"key":"b3","series-title":"Infect Dis Poverty","first-page":"71","article-title":"Childhood suffering: hyper endemic echinococcosis in Qinghai-Tibetan primary school students, China","volume":"7","author":"Han","year":"2018"},{"key":"b4","series-title":"Int J Infect Dis","first-page":"87","article-title":"Ex vivo liver resection and autotransplantation versus allotransplantation for end-stage hepatic alveolar echinococcosis","volume":"79","author":"Shen","year":"2019"},{"key":"b5","series-title":"Am J Trop Med Hyg","first-page":"674","article-title":"Epidemiology of echinococcosis among schoolchildren in Golog Tibetan Autonomous Prefecture, Qinghai, China","volume":"96","author":"Cai","year":"2017"},{"key":"b6","series-title":"Linchuang Xiaoer Waike Zazhi","first-page":"537","article-title":"Autologous liver transplantation for children with isolated or semi-isolated liver resection\u2014a new treatment modality for unresectable liver tumors","volume":"16","author":"Shi","year":"2017"},{"key":"b7","series-title":"Am J Transplant","first-page":"615","article-title":"Ex vivo liver resection and autotransplantation for end-stage alveolar echinococcosis: a case series","volume":"16","author":"Wen","year":"2016"},{"key":"b8","series-title":"Oncol Lett","first-page":"2199","article-title":"Ex vivo hepatectomy and partial liver autotransplantation for hepatoid adenocarcinoma: a case report","volume":"9","author":"Wang","year":"2015"},{"key":"b9","series-title":"Indian J Gastroenterol","first-page":"222","article-title":"Liver resection under hypothermic total vascular exclusion","volume":"32","author":"Govil","year":"2013"},{"key":"b10","series-title":"Medicine (Baltimore)","first-page":"e27075","article-title":"Application of ex vivo liver resection and autotransplantation in treating Budd-Chiari syndrome secondary to end-stage hepatic alveolar echinococcosis: a case series","volume":"100","author":"Wang","year":"2021"},{"key":"b11","series-title":"Surg Oncol","first-page":"188","article-title":"Postoperative liver volume was accurately predicted by a medical image three dimensional visualization system in hepatectomy for liver cancer","volume":"26","author":"Cai","year":"2017"},{"key":"b12","series-title":"Zhonghua Xiaoerwaike Zazhi","first-page":"4","article-title":"Extracorporeal circulation-assisted semi-ex vivo hepatectomy with autologous liver transplantation for complex liver tumors in children","volume":"39","author":"Kang","year":"2018"}],"container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/109\/3\/article-p640.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/109\/3\/article-p640.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/109\/3\/article-p640.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T13:56:24Z","timestamp":1694008584000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/109\/3\/article-p640.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9,6]]},"references-count":12,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.23-0276","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,9,6]]}}}