{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,5]],"date-time":"2025-12-05T03:23:36Z","timestamp":1764905016139},"reference-count":11,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,3,6]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>Type 2 leprosy reaction is a type of acute inflammation that predominantly affects borderline lepromatous leprosy and lepromatous leprosy patients and occurs before, during, or after therapy. The atypical variant, which resembles Sweet syndrome, could easily lead to misdiagnosis. Here, we report a case of a 52-year-old man who presented with type 2 leprosy reaction that mimicked Sweet syndrome. In addition, we review published cases and summarize their features to raise awareness of this atypical variant to enable improved diagnosis and management.<\/jats:p>","DOI":"10.4269\/ajtmh.23-0333","type":"journal-article","created":{"date-parts":[[2024,2,13]],"date-time":"2024-02-13T20:51:20Z","timestamp":1707857480000},"page":"487-490","source":"Crossref","is-referenced-by-count":2,"title":["Case Report: Type 2 Leprosy Reaction Mimicking Sweet Syndrome: A Case Report and Literature Review"],"prefix":"10.4269","volume":"110","author":[{"given":"Chengbei","family":"Bao","sequence":"first","affiliation":[{"name":"Department of Dermatology, First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China;"},{"name":"Key Laboratory of Skin Cancer of Fujian Higher Education Institutions, First Affiliated Hospital, Fujian Medical University, Fuzhou, China;"},{"name":"Fujian Dermatology and Venereology Research Institute, First Affiliated Hospital, Fujian Medical University, Fuzhou, China;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiuyun","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Dermatology, First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China;"},{"name":"Key Laboratory of Skin Cancer of Fujian Higher Education Institutions, First Affiliated Hospital, Fujian Medical University, Fuzhou, China;"},{"name":"Fujian Dermatology and Venereology Research Institute, First Affiliated Hospital, Fujian Medical University, Fuzhou, China;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying","family":"Zou","sequence":"additional","affiliation":[{"name":"Department of Dermatology, First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China;"},{"name":"Key Laboratory of Skin Cancer of Fujian Higher Education Institutions, First Affiliated Hospital, Fujian Medical University, Fuzhou, China;"},{"name":"Fujian Dermatology and Venereology Research Institute, First Affiliated Hospital, Fujian Medical University, Fuzhou, China;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhixun","family":"Xiao","sequence":"additional","affiliation":[{"name":"Department of Dermatology, First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China;"},{"name":"Key Laboratory of Skin Cancer of Fujian Higher Education Institutions, First Affiliated Hospital, Fujian Medical University, Fuzhou, China;"},{"name":"Fujian Dermatology and Venereology Research Institute, First Affiliated Hospital, Fujian Medical University, Fuzhou, China;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bo","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Dermatology, First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China;"},{"name":"Key Laboratory of Skin Cancer of Fujian Higher Education Institutions, First Affiliated Hospital, Fujian Medical University, Fuzhou, China;"},{"name":"Fujian Dermatology and Venereology Research Institute, First Affiliated Hospital, Fujian Medical University, Fuzhou, China;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ting","family":"Gong","sequence":"additional","affiliation":[{"name":"Department of Dermatology, First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China;"},{"name":"Central Laboratory, First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chao","family":"Ji","sequence":"additional","affiliation":[{"name":"Department of Dermatology, First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China;"},{"name":"Key Laboratory of Skin Cancer of Fujian Higher Education Institutions, First Affiliated Hospital, Fujian Medical University, Fuzhou, China;"},{"name":"Fujian Dermatology and Venereology Research Institute, First Affiliated Hospital, Fujian Medical University, Fuzhou, China;"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"b1","series-title":"J Eur Acad Dermatol Venereol","first-page":"1205","article-title":"Position statement: LEPROSY: diagnosis, treatment and follow-up","volume":"33","author":"Alemu Belachew","year":"2019"},{"key":"b2","series-title":"J Dtsch Dermatol Ges","first-page":"1133","article-title":"Atypical presentations of erythema nodosum leprosum: diagnostic and therapeutic aspects","volume":"19","author":"Alakad","year":"2021"},{"key":"b3","series-title":"Lepr Rev","article-title":"The diagnostic dilemma of erythema nodosum leprosum - a clinicohistological study","volume":"88","author":"Chatterjee","year":"2017"},{"key":"b4","series-title":"J Am Acad Dermatol","first-page":"1","article-title":"Leprosy: clinical aspects and diagnostic techniques","volume":"83","author":"Maymone","year":"2020"},{"key":"b5","series-title":"Front Immunol","first-page":"414","article-title":"Insights into the pathogenesis of Sweet\u2019s syndrome","volume":"10","author":"Heath","year":"2019"},{"key":"b6","series-title":"Actas Dermosifiliogr","first-page":"369","article-title":"Sweet syndrome: a review and update","volume":"107","author":"Villarreal-Villarreal","year":"2016"},{"key":"b7","series-title":"JAMA Dermatol","first-page":"640","article-title":"Incidence of and factors associated with leprosy among household contacts of patients with leprosy in Brazil","volume":"156","author":"Teixeira","year":"2020"},{"key":"b8","series-title":"PLoS Negl Trop Dis","first-page":"e0008678","article-title":"Thalidomide in the treatment of erythema nodosum leprosum (ENL) in an outpatient setting: a five-year retrospective analysis from a leprosy referral centre in India","volume":"14","author":"Upputuri","year":"2020"},{"key":"b9","year":"2018"},{"key":"b10","series-title":"PLoS Negl Trop Dis","first-page":"e0006706","article-title":"Evaluation of auramine O staining and conventional PCR for leprosy diagnosis: a comparative cross-sectional study from Ethiopia","volume":"12","author":"Girma","year":"2018"},{"key":"b11","series-title":"Br J Dermatol","first-page":"254","article-title":"Thalidomide: dermatological indications, mechanisms of action and side-effects","volume":"153","author":"Wu","year":"2005"}],"container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/110\/3\/article-p487.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/110\/3\/article-p487.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/110\/3\/article-p487.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,6]],"date-time":"2024-03-06T13:57:36Z","timestamp":1709733456000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/110\/3\/article-p487.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,6]]},"references-count":11,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.23-0333","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3,6]]}}}