{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,12,4]],"date-time":"2024-12-04T15:40:15Z","timestamp":1733326815685,"version":"3.30.1"},"reference-count":49,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"6","license":[{"start":{"date-parts":[[2024,12,4]],"date-time":"2024-12-04T00:00:00Z","timestamp":1733270400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,12,4]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>We report the frequency and associated factors of tuberculosis (TB) and parasite coinfection from newly diagnosed pulmonary TB patients (TB+) and non-TB participants (TB\u2212) from the Regional Tuberculosis Control Center, households, and health facilities in Bobo-Dioulasso from 2019 to 2021. Biological samples were examined for parasite infection using direct microscopy, concentration techniques, and the immunochromatographic rapid test. Data were analyzed using STATA 14. Of a total of 192 participants involved, 95 were TB+ and 97 were non-TB. There was no statistically significant difference in parasitic infections between the two groups, although it was higher in TB+ than TB\u2212 (69.5% [66\/95] versus 55.7% [54\/97]; <jats:italic>P<\/jats:italic> = 0.07). Protozoal infection prevalence was significantly higher in patients with TB+ than in those TB\u2212 (61.1% versus 37.1%; <jats:italic>P<\/jats:italic> = 0.001). Specifically, <jats:italic>Entamoeba<\/jats:italic> spp. and <jats:italic>Cryptosporidium<\/jats:italic> spp. followed this pattern with 35.8% versus 19.6% (<jats:italic>P<\/jats:italic> = 0.01) and 22.1% versus 8.3% (<jats:italic>P<\/jats:italic> = 0.007), respectively. Although higher in TB+ patients, helminthiasis frequency was not significantly different between the two groups (23.2% versus 15.5%; <jats:italic>P<\/jats:italic> = 0.2). Helminth species were <jats:italic>Schistosomia mansoni<\/jats:italic> (17.9% versus 12.4%), <jats:italic>Dicrocoelium dendriticum<\/jats:italic> (3.2% versus 1.0%), <jats:italic>Enterobius vermicularis<\/jats:italic> (2.1% versus 2.1%), <jats:italic>Wuchereria bancrofti<\/jats:italic> (1.1% versus 0.0%), and <jats:italic>Hymenolepis nana<\/jats:italic> (1.1% versus 0.0%). Illiteracy (adjusted odds ratio [aOR]: 2.5; 95% CI: 1.0\u20136.1), smoking (aOR: 2.4; 95% CI: 1.1\u20135.3), and handwashing after defecation (aOR: 2.4; 95% CI: 1.2\u20134.7) were associated with parasites. This study reported a high frequency of parasite coinfection in TB patients. These findings suggest the need for adequate health education for behavioral change and systematic diagnosing of parasites in TB patients for better coinfection management.<\/jats:p>","DOI":"10.4269\/ajtmh.23-0346","type":"journal-article","created":{"date-parts":[[2024,9,24]],"date-time":"2024-09-24T15:39:39Z","timestamp":1727192379000},"page":"1265-1272","source":"Crossref","is-referenced-by-count":0,"title":["Intestinal Protozoa, Helminth Infection, and Associated Factors among Tuberculosis Patients and Nontuberculosis Persons in Bobo-Dioulasso City, Burkina Faso"],"prefix":"10.4269","volume":"111","author":[{"given":"Diakourga Arthur","family":"Djibougou","sequence":"first","affiliation":[{"name":"Universit\u00e9 Nazi BONI, Bobo-Dioulasso, Burkina Faso;"},{"name":"Centre MURAZ\/Institut National de Sant\u00e9 Publique, Bobo-Dioulasso, Burkina Faso;"},{"name":"Institut de Recherche en Sciences de la Sant\u00e9\/Centre National de Recherche Scientifique et Technologique, Ouagadougou, Burkina Faso;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gloria Ivy","family":"Mensah","sequence":"additional","affiliation":[{"name":"Department of Bacteriology, Noguchi Memorial Institute for Medical Research, College of Health Sciences, University of Ghana, Legon, Accra, Ghana;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mamoudou","family":"Ciss\u00e9","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Nazi BONI, Bobo-Dioulasso, Burkina Faso;"},{"name":"Centre MURAZ\/Institut National de Sant\u00e9 Publique, Bobo-Dioulasso, Burkina Faso;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"To\u00e9","family":"Inoussa","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Nazi BONI, Bobo-Dioulasso, Burkina Faso;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leon Tinnoga","family":"Sawadogo","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Nazi BONI, Bobo-Dioulasso, Burkina Faso;"},{"name":"Programme National Tuberculose, Ministry of Health, Ouagadougou, Burkina Faso;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adjima","family":"Combary","sequence":"additional","affiliation":[{"name":"Programme National Tuberculose, Ministry of Health, Ouagadougou, Burkina Faso;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adama","family":"Sanou","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Nazi BONI, Bobo-Dioulasso, Burkina Faso;"},{"name":"Centre MURAZ\/Institut National de Sant\u00e9 Publique, Bobo-Dioulasso, Burkina Faso;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bassirou","family":"Bonfoh","sequence":"additional","affiliation":[{"name":"Centre Suisse de Recherches Scientifique de C\u00f4te d\u2019Ivoire, Abidjan, C\u00f4te d\u2019Ivoire;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kennedy Kwasi","family":"Addo","sequence":"additional","affiliation":[{"name":"Department of Bacteriology, Noguchi Memorial Institute for Medical Research, College of Health Sciences, University of Ghana, Legon, Accra, Ghana;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adrien Marie Gaston","family":"Belem","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Nazi BONI, Bobo-Dioulasso, Burkina Faso;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cl\u00e9ment Zieml\u00e9","family":"Meda","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Nazi BONI, Bobo-Dioulasso, Burkina Faso;"},{"name":"Centre MURAZ\/Institut National de Sant\u00e9 Publique, Bobo-Dioulasso, Burkina Faso;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roch Konbobr","family":"Dabir\u00e9","sequence":"additional","affiliation":[{"name":"Centre MURAZ\/Institut National de Sant\u00e9 Publique, Bobo-Dioulasso, Burkina Faso;"},{"name":"Institut de Recherche en Sciences de la Sant\u00e9\/Centre National de Recherche Scientifique et Technologique, Ouagadougou, Burkina Faso;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Achille","family":"Kabor\u00e9","sequence":"additional","affiliation":[{"name":"Family Health International 360 (FHI 360), Washington, District of Columbia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Potiandi Serge","family":"Diagbouga","sequence":"additional","affiliation":[{"name":"Institut de Recherche en Sciences de la Sant\u00e9\/Centre National de Recherche Scientifique et Technologique, Ouagadougou, Burkina Faso;"},{"name":"Etudes Formation et Recherches D\u00e9veloppement en Sant\u00e9 (EFORDS), Ouagadougou, Burkina Faso"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"b1","series-title":"Nature","first-page":"S16","article-title":"Tuberculosis is the oldest pandemic, and poverty makes it continue","volume":"605","author":"Moutinho","year":"2022"},{"year":"2021","series-title":"Meeting Report of the WHO Expert Consultation on the Definition of Extensively Drug\u2010Resistant Tuberculosis: 27\u201329 October 2020","key":"b2"},{"key":"b3","series-title":"PLoS Negl Trop Dis","first-page":"e0005342","article-title":"Prevalence and clinical relevance of helminth coinfections among tuberculosis patients in urban Tanzania","volume":"11","author":"Mhimbira","year":"2017"},{"key":"b4","series-title":"Glob Health Res Policy","first-page":"9","article-title":"Prevalence of soil-transmitted helminths infections among preschool and school-age children in Ethiopia: A systematic review and meta-analysis","volume":"7","author":"Chelkeba","year":"2022"},{"key":"b5","series-title":"Trop Med Int Health","first-page":"551","article-title":"Are intestinal helminths risk factors for developing active tuberculosis?","volume":"11","author":"Elias","year":"2006"},{"key":"b6","series-title":"Nat Immunol","first-page":"1118","article-title":"Effect of helminth-induced immunity on infections with microbial pathogens","volume":"14","author":"Salgame","year":"2013"},{"key":"b7","series-title":"Open Forum Infect Dis","first-page":"ofac541","article-title":"Prevalence of intestinal helminth coinfection in drug-resistant tuberculosis in Uganda","volume":"9","author":"Baluku","year":"2022"},{"key":"b8","series-title":"PLoS Negl Trop Dis","first-page":"e0008069","article-title":"Interactions between helminths and tuberculosis infections: Implications for tuberculosis diagnosis and vaccination in Africa","volume":"14","author":"Cadmus","year":"2020"},{"key":"b9","series-title":"Clin Microbiol Rev","first-page":"585","article-title":"Helminth infections and host immune regulation","volume":"25","author":"McSorley","year":"2012"},{"key":"b10","series-title":"PLoS One","first-page":"e42901","article-title":"The impact of asymptomatic helminth coinfection in patients with newly diagnosed tuberculosis in north-west Ethiopia","volume":"7","author":"Abate","year":"2012"},{"key":"b11","series-title":"Parasite Immunol","first-page":"483","article-title":"Immune modulation by helminthic infections: Worms and viral infections","volume":"28","author":"Kamal","year":"2006"},{"key":"b12","series-title":"Parasite Immunol","first-page":"304","article-title":"Looking beyond the induction of Th2 responses to explain immunomodulation by helminths","volume":"37","author":"Nutman","year":"2015"},{"key":"b13","series-title":"BMC Infect Dis","first-page":"517","article-title":"Immunological recovery in tuberculosis\/HIV co-infected patients on antiretroviral therapy: Implication for tuberculosis preventive therapy","volume":"17","author":"Karo","year":"2017"},{"key":"b14","series-title":"J Microb Biochem Technol","first-page":"179","article-title":"Prevalence of smear positive tuberculosis, intestinal parasites and their coinfection among tuberculosis suspects in Gondar University Hospital and Gondar Poly Clinic, north west Ethiopia","volume":"6","author":"Alemayehu","year":"2014"},{"key":"b15","series-title":"BMC Res Notes","first-page":"632","article-title":"Intestinal parasitosis and anaemia among patients in a health center, North Ethiopia","volume":"10","author":"Alemu","year":"2017"},{"key":"b16","series-title":"Rev Soc Bras Med Trop","first-page":"533","article-title":"Intestinal nematodes and pulmonary tuberculosis","volume":"35","author":"Trist\u00e3o-S\u00e1","year":"2002"},{"key":"b17","series-title":"BMC Infect Dis","first-page":"510","article-title":"Intestinal parasites coinfection among tuberculosis patients in Ethiopia: A systematic review and meta-analysis","volume":"20","author":"Alemu","year":"2020"},{"key":"b18","series-title":"J Acquir Immune Defic Syndr","first-page":"157","article-title":"Schistosoma mansoni infection is associated with a higher probability of tuberculosis disease in HIV-infected adults in Kenya","volume":"86","author":"McLaughlin","year":"2021"},{"key":"b19","series-title":"Acta Trop","first-page":"19","article-title":"Prevalence and risk factors of intestinal protozoan and helminth infections among pulmonary tuberculosis patients without HIV infection in a rural county in P. R. China","volume":"149","author":"Li","year":"2015"},{"key":"b20","series-title":"Med Sante Trop","first-page":"267","article-title":"Prevalence of schistosomiasis and soil-transmitted helminth infections among schoolchildren in Burkina Faso","volume":"26","author":"Bagayan","year":"2016"},{"key":"b21","series-title":"Infect Dis Poverty","first-page":"41","article-title":"Soil-transmitted helminth infection in school age children in Sierra Leone after a decade of preventive chemotherapy interventions","volume":"8","author":"Bah","year":"2019"},{"key":"b22","series-title":"Parasit Vectors","first-page":"185","article-title":"Prevalence and risk factors of Schistosoma mansoni infection among preschool-aged children from Panamasso village, Burkina Faso","volume":"14","author":"Cisse","year":"2021"},{"key":"b23","series-title":"PLoS Negl Trop Dis","first-page":"e0006241","article-title":"Results of the first mapping of soil-transmitted helminths in Benin: Evidence of countrywide hookworm predominance","volume":"12","author":"Ibikounl\u00e9","year":"2018"},{"key":"b24","series-title":"Parasit Vectors","first-page":"162","article-title":"Bayesian risk profiling of soil-transmitted helminth infections and estimates of preventive chemotherapy for school-aged children in C\u00f4te d\u2019Ivoire","volume":"9","author":"Yapi","year":"2016"},{"key":"b25","series-title":"Infect Dis Poverty","first-page":"32","article-title":"Prevalence of intestinal opportunistic parasites infections in the University Hospital of Bobo-Dioulasso, Burkina Faso","volume":"4","author":"Sangar\u00e9","year":"2015"},{"year":"2022","key":"b26"},{"key":"b27","series-title":"F1000 Res","first-page":"1719","article-title":"Frequencies of gastrointestinal parasites among students of primary school in Al Kalakla Locality, Khartoum State, Sudan: A cross-sectional study","volume":"8","author":"Abdalazim Hassan","year":"2020"},{"key":"b28","series-title":"Clin Microbiol Rev","first-page":"e00025","article-title":"Practical guidance for clinical microbiology laboratories: Laboratory diagnosis of parasites from the gastrointestinal tract","volume":"31","author":"Garcia","year":"2018"},{"key":"b29","series-title":"Parasite Immunol","first-page":"497","article-title":"Coinfection of helminths and malaria: Modulation of the immune responses to malaria","volume":"28","author":"Hartgers","year":"2006"},{"key":"b30","series-title":"Saudi Med J","first-page":"1204","article-title":"Cryptosporidiosis and other intestinal parasitic infections in patients with chronic diarrhea","volume":"25","author":"Mahdi","year":"2004"},{"key":"b31","series-title":"Am J Trop Med Hyg","first-page":"106","article-title":"Intestinal parasite coinfection among pulmonary tuberculosis cases without human immunodeficiency virus infection in a rural county in China","volume":"90","author":"Li","year":"2014"},{"key":"b32","series-title":"Trans R Soc Trop Med Hyg","first-page":"234","article-title":"Frequency, associated factors and clinical symptoms of intestinal parasites among tuberculosis and non-tuberculosis groups in Iran: A comparative cross-sectional study","volume":"113","author":"Taghipour","year":"2019"},{"key":"b33","series-title":"BMC Infect Dis","first-page":"68","article-title":"Intestinal helminth coinfection and associated factors among tuberculosis patients in Arba Minch, Ethiopia","volume":"17","author":"Alemu","year":"2017"},{"key":"b34","series-title":"Sci J Public Health","first-page":"10","article-title":"Prevalence of intestinal parasites coinfection and associated factors among pulmonary tuberculosis patients in Adama Town, East Shoa, Oromia, Ethiopia","volume":"10","author":"Lemma","year":"2022"},{"key":"b35","series-title":"J Parasitol Res","first-page":"e9372145","article-title":"Prevalence of intestinal parasites and associated factors among pulmonary tuberculosis suspected patients attending University of Gondar Hospital, Gondar, Northwest Ethiopia","volume":"2018","author":"Tegegne","year":"2018"},{"key":"b36","series-title":"Sciences de la Sant\u00e9","first-page":"87","article-title":"Pr\u00e9valence de l\u2019ankylostomiase avant et apr\u00e8s la mise en oeuvre du traitement de masse \u00e0 l\u2019ivermectine et \u00e0 l\u2019albendazole au Burkina Faso","volume":"34","author":"Ciss\u00e9","year":"2011"},{"key":"b37","series-title":"Rev Saude Publica","first-page":"176","article-title":"Tuberculosis and intestinal parasitism among indigenous people in the Brazilian Amazon region","volume":"43","author":"B\u00f3ia","year":"2009"},{"key":"b38","series-title":"Microb Pathog","first-page":"119","article-title":"Looking in amoebae as a source of mycobacteria","volume":"77","author":"Drancourt","year":"2014"},{"key":"b39","series-title":"PLoS One","first-page":"e20499","article-title":"Mycobacterium tuberculosis complex mycobacteria as amoeba-resistant organisms","volume":"6","author":"Mba Medie","year":"2011"},{"key":"b40","series-title":"Emerg Infect Dis","first-page":"1758","article-title":"Fecal excretion of Mycobacterium leprae, Burkina Faso","volume":"27","author":"Millogo","year":"2021"},{"key":"b41","series-title":"Int J Pharma Sci","first-page":"1092","article-title":"The case control studies of HIV and intestinal parasitic infections rate in active pulmonary tuberculosis patients in Woldia General Hospital and Health Center in North Wollo, Amhara Region, Ethiopia","volume":"5","author":"Hailu","year":"2015"},{"key":"b42","series-title":"Acta Trop","first-page":"197","article-title":"Association between enteric protozoan parasites and gastrointestinal illness among HIV- and tuberculosis-infected individuals in the Chowke district, southern Mozambique","volume":"170","author":"Irisarri-Guti\u00e9rrez","year":"2017"},{"key":"b43","series-title":"Clin Exp Immunol","first-page":"45","article-title":"Intestinal helminth coinfection has a negative impact on both anti-Mycobacterium tuberculosis immunity and clinical response to tuberculosis therapy","volume":"147","author":"Resende Co","year":"2007"},{"key":"b44","series-title":"PLoS Negl Trop Dis","first-page":"e0005817","article-title":"Mixed Th1 and Th2 Mycobacterium tuberculosis-specific CD4 T cell responses in patients with active pulmonary tuberculosis from Tanzania","volume":"11","author":"Amelio","year":"2017"},{"key":"b45","series-title":"Infect Dis Poverty","first-page":"88","article-title":"High helminthic coinfection in tuberculosis patients with undernutritional status in northeastern Ethiopia","volume":"8","author":"Gashaw","year":"2019"},{"key":"b46","series-title":"BMC Infect Dis","first-page":"407","article-title":"Intestinal parasites coinfection and associated factors among active pulmonary tuberculosis patients in selected health centers, Addis Ababa, Ethiopia: Unmatched case control study","volume":"19","author":"Alemu","year":"2019"},{"key":"b47","series-title":"Rev Soc Bras Med Trop","first-page":"853","article-title":"Prevalence of and risk factors for intestinal parasite infections in pediatric patients admitted to public hospitals in southern Brazil","volume":"50","author":"de Almeida","year":"2017"},{"key":"b48","series-title":"Pathogens","first-page":"1274","article-title":"The relationship of latent toxoplasmosis and cigarette smoking: Seroprevalence, risk factor, and case-control study in Fars Province, southern Iran","volume":"11","author":"Bahreini","year":"2022"},{"key":"b49","series-title":"ScientificWorldJournal","first-page":"3905963","article-title":"Prevalence and associated risk factors of human intestinal helminths parasitic infections in Ethiopia: A systematic review and meta-analysis","volume":"2022","author":"Liyih","year":"2022"}],"container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/111\/6\/article-p1265.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/111\/6\/article-p1265.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/111\/6\/article-p1265.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,4]],"date-time":"2024-12-04T15:28:50Z","timestamp":1733326130000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/111\/6\/article-p1265.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,4]]},"references-count":49,"journal-issue":{"issue":"6"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.23-0346","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"type":"print","value":"0002-9637"},{"type":"electronic","value":"1476-1645"}],"subject":[],"published":{"date-parts":[[2024,12,4]]}}}