{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T04:24:00Z","timestamp":1771647840541,"version":"3.50.1"},"reference-count":25,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"3","license":[{"start":{"date-parts":[[2024,3,6]],"date-time":"2024-03-06T00:00:00Z","timestamp":1709683200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,3,6]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p><jats:italic>Anopheles darlingi<\/jats:italic> is the primary malaria vector in the Amazon region and is highly susceptible to both <jats:italic>Plasmodium vivax<\/jats:italic> and <jats:italic>Plasmodium falciparum<\/jats:italic> parasites. Although anopheline mosquitoes may develop melanotic encapsulation in response to <jats:italic>Plasmodium<\/jats:italic> parasites, there is no record of <jats:italic>An. darlingi<\/jats:italic> exhibiting a melanization response to <jats:italic>P. vivax<\/jats:italic>, the main malaria parasite in the Americas. Here, we report the occurrence of <jats:italic>P. vivax<\/jats:italic> sporozoite melanization in <jats:italic>An. darlingi<\/jats:italic> mosquitoes.<\/jats:p>","DOI":"10.4269\/ajtmh.23-0349","type":"journal-article","created":{"date-parts":[[2024,2,13]],"date-time":"2024-02-13T20:51:22Z","timestamp":1707857482000},"page":"444-447","source":"Crossref","is-referenced-by-count":4,"title":["Case Report: Plasmodium vivax Sporozoite Melanization in the Midgut and Salivary Gland of the Malaria Vector Anopheles darlingi"],"prefix":"10.4269","volume":"110","author":[{"given":"Najara Akira Costa","family":"dos Santos","sequence":"first","affiliation":[{"name":"Plataforma de Produ\u00e7\u00e3o e Infec\u00e7\u00e3o de Vetores da Mal\u00e1ria- PIVEM, Laborat\u00f3rio de Entomologia, Fiocruz Rond\u00f4nia, Porto Velho, Rond\u00f4nia, Brazil;"},{"name":"Instituto Nacional de Epidemiologia da Amaz\u00f4nia Ocidental (INCT-EpiAMO), Porto Velho, RO, Brazil;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandra da Silva","family":"Bastos","sequence":"additional","affiliation":[{"name":"Plataforma de Produ\u00e7\u00e3o e Infec\u00e7\u00e3o de Vetores da Mal\u00e1ria- PIVEM, Laborat\u00f3rio de Entomologia, Fiocruz Rond\u00f4nia, Porto Velho, Rond\u00f4nia, Brazil;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00e9ssica Evangelista","family":"Ara\u00fajo","sequence":"additional","affiliation":[{"name":"Plataforma de Produ\u00e7\u00e3o e Infec\u00e7\u00e3o de Vetores da Mal\u00e1ria- PIVEM, Laborat\u00f3rio de Entomologia, Fiocruz Rond\u00f4nia, Porto Velho, Rond\u00f4nia, Brazil;"},{"name":"Programa de P\u00f3s-gradua\u00e7\u00e3o em Biologia Experimental \u2013 Universidade Federal de Rond\u00f4nia\/Fiocruz Rond\u00f4nia, Porto Velho, Rond\u00f4nia, Brazil;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Daniel Costa","family":"Pontual","sequence":"additional","affiliation":[{"name":"Plataforma de Produ\u00e7\u00e3o e Infec\u00e7\u00e3o de Vetores da Mal\u00e1ria- PIVEM, Laborat\u00f3rio de Entomologia, Fiocruz Rond\u00f4nia, Porto Velho, Rond\u00f4nia, Brazil;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jansen Fernandes","family":"Medeiros","sequence":"additional","affiliation":[{"name":"Plataforma de Produ\u00e7\u00e3o e Infec\u00e7\u00e3o de Vetores da Mal\u00e1ria- PIVEM, Laborat\u00f3rio de Entomologia, Fiocruz Rond\u00f4nia, Porto Velho, Rond\u00f4nia, Brazil;"},{"name":"Instituto Nacional de Epidemiologia da Amaz\u00f4nia Ocidental (INCT-EpiAMO), Porto Velho, RO, Brazil;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph Michael","family":"Vinetz","sequence":"additional","affiliation":[{"name":"Section of Infectious Diseases, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, United States of America;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maisa da Silva","family":"Araujo","sequence":"additional","affiliation":[{"name":"Plataforma de Produ\u00e7\u00e3o e Infec\u00e7\u00e3o de Vetores da Mal\u00e1ria- PIVEM, Laborat\u00f3rio de Entomologia, Fiocruz Rond\u00f4nia, Porto Velho, Rond\u00f4nia, Brazil;"},{"name":"Instituto Nacional de Epidemiologia da Amaz\u00f4nia Ocidental (INCT-EpiAMO), Porto Velho, RO, Brazil;"},{"name":"Programa de P\u00f3s-Gradua\u00e7\u00e3o em Conserva\u00e7\u00e3o e uso de Recursos Naturais \u2013 PPGReN, Funda\u00e7\u00e3o Universidade Federal de Rond\u00f4nia, Porto Velho, Rond\u00f4nia, Brazil;"},{"name":"Laborat\u00f3rio de Pesquisa Translacional e Cl\u00ednica, Centro de Pesquisa em Medicina Tropical, Porto Velho, Rond\u00f4nia, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"b1","series-title":"World Malaria 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