{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T07:01:50Z","timestamp":1775890910448,"version":"3.50.1"},"reference-count":24,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,12,6]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>Prostatic abscess is a common manifestation of melioidosis in men, but the characteristics of female genitourinary melioidosis are incompletely defined. There were 453 cases of melioidosis in Far North Queensland, tropical Australia, between January 1998 and April 2023; genitourinary involvement was less common in women than in men (13\/140 [9%] versus 76\/313 [24%], odds ratio [95% confidence interval]: 0.32 [0.17\u20130.60], <jats:italic>P =<\/jats:italic> 0.0004). In 11 of these 13 (85%) women, other organs were also affected. The two women with disease involving only the genitourinary tract had underlying anatomical abnormalities: one had an ovarian malignancy, the only case to involve the female reproductive system in the cohort, while the other had a urethral diverticulum. In 3 of 13 (23%) women, genitourinary involvement was identified only with computed tomography, emphasizing the importance of early imaging of patients with melioidosis to identify unexpected foci of disease and to inform the optimal duration of antibiotic therapy.<\/jats:p>","DOI":"10.4269\/ajtmh.23-0350","type":"journal-article","created":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T16:29:32Z","timestamp":1697473772000},"page":"1233-1237","source":"Crossref","is-referenced-by-count":3,"title":["Melioidosis of the Female Genitourinary Tract"],"prefix":"10.4269","volume":"109","author":[{"given":"Kelly","family":"Baker","sequence":"first","affiliation":[{"name":"Department of Medicine, Cairns Hospital, Cairns, Australia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon","family":"Smith","sequence":"additional","affiliation":[{"name":"Department of Medicine, Cairns Hospital, Cairns, Australia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James","family":"Stewart","sequence":"additional","affiliation":[{"name":"Department of Medicine, Cairns Hospital, Cairns, Australia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Grant","family":"Withey","sequence":"additional","affiliation":[{"name":"Department of Radiology, Cairns Hospital, Cairns, Australia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Madeleine","family":"Bain","sequence":"additional","affiliation":[{"name":"Department of Surgery, Cairns Hospital, Cairns, Australia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon","family":"Pridgeon","sequence":"additional","affiliation":[{"name":"Department of Surgery, Cairns Hospital, Cairns, Australia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josh","family":"Hanson","sequence":"additional","affiliation":[{"name":"Department of Medicine, Cairns Hospital, Cairns, Australia;"},{"name":"The Kirby Institute, University of New South Wales, Sydney, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"b1","series-title":"Curr Opin Infect Dis","first-page":"517","article-title":"Melioidosis and Burkholderia pseudomallei: progress in epidemiology, diagnosis, treatment and vaccination","volume":"35","author":"Currie","year":"2022"},{"key":"b2","series-title":"Trop Med Infect Dis","first-page":"27","article-title":"Melioidosis: an Australian perspective","volume":"3","author":"Smith","year":"2018"},{"key":"b3","series-title":"Lancet Infect Dis","first-page":"1737","article-title":"The Darwin Prospective Melioidosis Study: a 30-year prospective, observational investigation","volume":"21","author":"Currie","year":"2021"},{"key":"b4","series-title":"J Urol","first-page":"542","article-title":"Prostatic abscess due to Burkholderia pseudomallei: 81 cases from a 19-year prospective melioidosis study","volume":"182","author":"Morse","year":"2009"},{"key":"b5","series-title":"Am J Trop Med Hyg","first-page":"227","article-title":"Prostatic abscess due to Burkholderia pseudomallei: facilitating diagnosis to optimize management","volume":"98","author":"Kozlowska","year":"2018"},{"key":"b6","series-title":"Med J Malaysia","first-page":"257","article-title":"Urogenital melioidosis: a review of clinical presentations, characteristic and outcomes","volume":"69","author":"Chong Vh","year":"2014"},{"key":"b7","series-title":"PLoS Negl Trop Dis","first-page":"e0005411","article-title":"The epidemiology and clinical features of melioidosis in Far North Queensland: implications for patient management","volume":"11","author":"Stewart","year":"2017"},{"key":"b8","series-title":"Ther Adv Urol","first-page":"1756287218814382","article-title":"Risk factors and predisposing conditions for urinary tract infection","volume":"11","author":"Storme","year":"2019"},{"key":"b9","series-title":"Indian J Med Res","first-page":"S71","article-title":"Female genital tuberculosis: revisited","volume":"148","author":"Sharma","year":"2018"},{"key":"b10","series-title":"N Engl J Med","first-page":"1171","article-title":"Mother-to-child transmission of Burkholderia pseudomallei.","volume":"344","author":"Abbink","year":"2001"},{"key":"b11","series-title":"Clin Infect Dis","first-page":"ciac111","article-title":"Melioidosis of the central nervous system; impact of the bimABm allele on patient presentation and outcome","volume":"2022","author":"Gora","year":"2022"},{"key":"b12","series-title":"Microbes Infect","first-page":"104","article-title":"Burkholderia pseudomallei strain type, based on pulsed-field gel electrophoresis, does not determine disease presentation in melioidosis","volume":"7","author":"Cheng","year":"2005"},{"key":"b13","series-title":"Lancet Reg Health Southeast Asia","article-title":"Characteristics and one year outcomes of melioidosis patients in Northeastern Thailand: a prospective, multicenter cohort study","volume":"9","author":"Chantratita","year":"2023"},{"key":"b14","series-title":"PLoS Negl Trop Dis","first-page":"e0009544","article-title":"Melioidosis \u2013 a disease of socioeconomic disadvantage","volume":"15","author":"Hanson","year":"2021"},{"key":"b15","series-title":"Diabetes Metab Syndr Obes","first-page":"129","article-title":"Urinary tract infections in patients with type 2 diabetes mellitus: review of prevalence, diagnosis, and management","volume":"8","author":"Nitzan","year":"2015"},{"key":"b16","series-title":"Eur J Immunol","first-page":"1092","article-title":"Diabetes alters immune response patterns to acute melioidosis in humans","volume":"49","author":"Kronsteiner","year":"2019"},{"key":"b17","series-title":"Emerg Infect Dis","first-page":"1538","article-title":"Intensity of rainfall and severity of melioidosis, Australia","volume":"9","author":"Currie","year":"2003"},{"key":"b18","series-title":"PLOS Glob Public Health","first-page":"e0000506","article-title":"The seasonality of infections in tropical Far North Queensland, Australia: a 21-year retrospective evaluation of the seasonal patterns of six endemic pathogens","volume":"2","author":"Fairhead","year":"2022"},{"key":"b19","series-title":"BMC Infect Dis","first-page":"201","article-title":"Disseminated melioidosis in early pregnancy \u2013 an unproven cause of foetal loss","volume":"20","author":"Chang","year":"2020"},{"key":"b20","series-title":"Ann Intern Med","first-page":"512","article-title":"Human-to-human transmission of Pseudomonas pseudomallei","volume":"83","author":"McCormick","year":"1975"},{"key":"b21","series-title":"Trans R Soc Trop Med Hyg","first-page":"629","article-title":"Prospective observational study of the frequency and features of intra-abdominal abscesses in patients with melioidosis in northeast Thailand","volume":"106","author":"Maude","year":"2012"},{"key":"b22","series-title":"J Am Coll Radiol","first-page":"S224","article-title":"ACR Appropriateness Criteria\u00ae acute pyelonephritis: 2022 update","volume":"19","year":"2022"},{"key":"b23","year":"2021"},{"key":"b24","series-title":"Emerg Infect Dis","first-page":"3119","article-title":"Increased incidence of melioidosis in Far North Queensland, Queensland, Australia, 1998\u20132019","volume":"27","author":"Smith","year":"2021"}],"container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/109\/6\/article-p1233.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/109\/6\/article-p1233.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/109\/6\/article-p1233.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,6]],"date-time":"2023-12-06T15:44:58Z","timestamp":1701877498000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/109\/6\/article-p1233.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,6]]},"references-count":24,"journal-issue":{"issue":"6"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.23-0350","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,12,6]]}}}