{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,1,4]],"date-time":"2024-01-04T00:14:29Z","timestamp":1704327269721},"reference-count":57,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,1,3]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>School-based mass deworming programs are implemented to reduce soil-transmitted helminth (STH) infection prevalence and intensity among school-aged children. However, previous studies debate the impact of deworming beyond the removal of worms. Hence, this study aimed to examine the effect of mass deworming on nutritional indicators in young Ethiopian schoolchildren. A school-based cross-sectional study was conducted among 1,036 participants from April to May 2020 in Jimma Town, Ethiopia. An interviewer-based questionnaire was administered to the children to gather data on sociodemographic, lifestyle variables, and deworming status. Anthropometric measurements were taken for the height and weight of the children. Stool samples were collected and analyzed for STH infection using direct wet mount microscopy and the Kato-Katz technique. In multivariate logistic regression analysis, deworming within the past 6 months or 1\u2009year was not significantly associated with underweight, stunting, and thinning. However, deworming within the past year was significantly associated with decreased weight-for-age z-score (adjusted mean difference = \u22120.245; 95% CI: \u22120.413 to \u22120.076; <jats:italic>P =<\/jats:italic> 0.004). Deworming in the past 6 months demonstrated a nonsignificant trend toward increased stunting (adjusted odds ratio = 1.258; 95% CI: 0.923\u20131.714; <jats:italic>P =<\/jats:italic> 0.145). This study provides evidence that deworming in the past 6 months or 1\u2009year was not significantly associated with underweight, stunting, and thinning. However, deworming within the past year was associated with a significantly decreased weight-for-age z-score in young Ethiopian schoolchildren of Jimma Town after adjustment for confounding variables.<\/jats:p>","DOI":"10.4269\/ajtmh.23-0376","type":"journal-article","created":{"date-parts":[[2023,12,11]],"date-time":"2023-12-11T14:39:41Z","timestamp":1702305581000},"page":"103-110","source":"Crossref","is-referenced-by-count":0,"title":["Decreased Weight-for-Age Associated with Mass Deworming among Young Ethiopian Schoolchildren in Jimma Town, Southwest Ethiopia: A School-Based Cross-Sectional Study"],"prefix":"10.4269","volume":"110","author":[{"given":"Kylie","family":"Geer","sequence":"first","affiliation":[{"name":"Department of Biology, Colgate University, Hamilton, New York;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zeleke","family":"Mekonnen","sequence":"additional","affiliation":[{"name":"Institute of Health, School of Medical Laboratory Sciences, Jimma University, Jimma, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bineyam","family":"Taye","sequence":"additional","affiliation":[{"name":"Department of Biology, Colgate University, Hamilton, New York;"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"b1","series-title":"Soil-Transmitted Helminth Infections.","year":"2022"},{"key":"b2","series-title":"Leaf-Nosed Bat.","year":"2009"},{"key":"b3","series-title":"Soil-Transmitted Helminthiases.","year":"2020"},{"key":"b4","series-title":"Parasit Vectors","first-page":"37","article-title":"Global numbers of infection and disease burden of soil transmitted helminth infections in 2010","volume":"7","year":"2014"},{"key":"b5","series-title":"Parasit Vectors","first-page":"119","article-title":"The nutritional impacts of soil-transmitted helminths infections among Orang Asli schoolchildren in rural Malaysia","volume":"5","year":"2012"},{"key":"b6","series-title":"J Nutr Metab","first-page":"8876851","article-title":"Prevalence and predictors of stunting among primary school children in northeast Ethiopia","volume":"2021","year":"2021"},{"key":"b7","series-title":"BMC Pediatr","first-page":"13","article-title":"Prevalence and intensity of Ascaris lumbricoides infections in relation to undernutrition among children in a tea plantation community, Sri Lanka: a cross-sectional study","volume":"18","year":"2018"},{"key":"b8","series-title":"BMC Public Health","first-page":"1204","article-title":"Association between intestinal worm infection and malnutrition among rural children aged 9\u201311 years old in Guizhou Province, China","volume":"19","year":"2019"},{"key":"b9","series-title":"Trans R Soc Trop Med Hyg","first-page":"204","article-title":"Stunting and helminth infection in early preschool-age children in a resource-poor community in the Amazon lowlands of Peru","volume":"105","year":"2011"},{"key":"b10","series-title":"PLoS Negl Trop Dis","first-page":"e3369","article-title":"Risk factors associated with malnutrition in one-year-old children living in the Peruvian Amazon","volume":"8","year":"2014"},{"key":"b11","series-title":"PLoS Negl Trop Dis","first-page":"e0010008","article-title":"Soil-transmitted helminth infections and nutritional indices among Filipino schoolchildren","volume":"15","year":"2021"},{"key":"b12","series-title":"Ann Trop Med Parasitol","first-page":"583","article-title":"Impact of intestinal helminthiases on the nutritional status of primary-school children in Osun state, south-western Nigeria","volume":"104","year":"2010"},{"key":"b13","series-title":"PLoS Negl Trop Dis","first-page":"e2378","article-title":"Soil-transmitted helminth infections and nutritional status in school-age children from rural communities in Honduras","volume":"7","year":"2013"},{"key":"b14","series-title":"BMC Public Health","first-page":"1270","article-title":"The high prevalence of intestinal parasitic infections is associated with stunting among children aged 6-59 months in Boricha Woreda, southern Ethiopia: a cross-sectional study","volume":"20","year":"2020"},{"key":"b15","series-title":"Int J Parasitol","first-page":"741","article-title":"Parasite risk factors for stunting in grade 5 students in a community of extreme poverty in Peru","volume":"36","year":"2006"},{"key":"b16","series-title":"PLoS Negl Trop Dis","first-page":"e1550","article-title":"Association between anaemia, iron deficiency anaemia, neglected parasitic infections and socioeconomic factors in rural children of West Malaysia","volume":"6","year":"2012"},{"key":"b17","series-title":"Helminth Control in School-Age Children: A Guide for Managers of Control Programmes","year":"2002"},{"key":"b18","series-title":"PLoS Negl Trop Dis","first-page":"e0006520","article-title":"Impact of a national deworming campaign on the prevalence of soil-transmitted helminthiasis in Uganda (2004\u20132016): implications for national control programs","volume":"12","year":"2018"},{"key":"b19","series-title":"Lancet","first-page":"287","article-title":"Differential effect of mass deworming and targeted deworming for soil-transmitted helminth control in children: a systematic review and meta-analysis","volume":"389","year":"2017"},{"key":"b20","series-title":"Parasit Vectors","first-page":"1","article-title":"Results of a national school-based deworming programme on soil-transmitted helminths infections and schistosomiasis in Kenya: 2012\u20132017","volume":"12","year":"2019"},{"key":"b21","series-title":"Parasit Vectors","first-page":"7","article-title":"Effects of deworming medication on anaemia among children aged 6-59 months in sub-Saharan Africa","volume":"15","year":"2022"},{"key":"b22","series-title":"Proc Natl Acad Sci USA","first-page":"e2023185118","article-title":"Twenty-year economic impacts of deworming","volume":"118","year":"2021"},{"key":"b23","series-title":"PLoS Negl Trop Dis","first-page":"e0009282","article-title":"Routine deworming during antenatal care decreases risk of neonatal mortality and low birthweight: a retrospective cohort of survey data","volume":"15","year":"2021"},{"key":"b24","series-title":"BMJ","first-page":"122","article-title":"Effect on weight gain of routinely giving albendazole to preschool children during child health days in Uganda: cluster randomised controlled trial","volume":"333","year":"2006"},{"key":"b25","series-title":"J Nutr","first-page":"656","article-title":"Weight gain of Kenyan school children infected with hookworm, Trichuris trichiura and Ascaris lumbricoides is improved following once- or twice-yearly treatment with albendazole","volume":"123","year":"1993"},{"key":"b26","series-title":"PLoS Negl Trop Dis","first-page":"e223","article-title":"Effects of deworming on malnourished preschool children in India: an open-labelled, cluster-randomized trial","volume":"2","year":"2008"},{"key":"b27","series-title":"J Nutr","first-page":"348","article-title":"Low dose daily iron supplementation improves iron status and appetite but not anemia, whereas quarterly anthelminthic treatment improves growth, appetite and anemia in Zanzibari preschool children","volume":"134","year":"2004"},{"key":"b28","series-title":"Am J Trop Med Hyg","first-page":"333","article-title":"Decreased parasite load and improved cognitive outcomes caused by deworming and consumption of multi-micronutrient fortified biscuits in rural Vietnamese schoolchildren","volume":"85","year":"2011"},{"key":"b29","series-title":"PLoS Negl Trop Dis","first-page":"e0007085","article-title":"The long run impact of early childhood deworming on numeracy and literacy: evidence from Uganda","volume":"13","year":"2019"},{"key":"b30","series-title":"Cochrane Database Syst Rev","first-page":"CD000371","article-title":"Deworming drugs for soil-transmitted intestinal worms in children: effects on nutritional indicators, haemoglobin, and school performance","year":"2015"},{"key":"b31","series-title":"Lancet Glob Health","first-page":"e40","article-title":"Mass deworming to improve developmental health and wellbeing of children in low-income and middle-income countries: a systematic review and network meta-analysis","volume":"5","year":"2017"},{"key":"b32","series-title":"Int Health","first-page":"i34","article-title":"Ethiopia and its steps to mobilize resources to achieve 2020 elimination and control goals for neglected tropical diseases webs joined can tie a lion","volume":"8","year":"2016"},{"key":"b33","series-title":"Ethiopia\u2019s National School-Based Deworming Programme To Treat 16.5 Million","year":"2015"},{"key":"b34","series-title":"Ethiop Med J","first-page":"75","article-title":"Ethiopia schistosomiasis and soil-transmitted helminthes control programme: progress and prospects","volume":"55","year":"2017"},{"key":"b35","series-title":"Parasit Vectors","first-page":"437","article-title":"National mapping of soil-transmitted helminth and schistosome infections in Ethiopia","volume":"13","year":"2020"},{"key":"b36","series-title":"PLoS Negl Trop Dis","first-page":"e0010408","article-title":"Longitudinal monitoring of prevalence and intensity of soil-transmitted helminth infections as part of community-wide mass drug administration within the Geshiyaro project in the Bolosso Sore district, Wolaita, Ethiopia","volume":"16","year":"2022"},{"key":"b37","series-title":"Front Epidemiol","article-title":"Feature selection and association rule learning identify risk factors of malnutrition among Ethiopian schoolchildren","volume":"3","author":"Russel","year":"2023"},{"key":"b38","series-title":"District Laboratory Practice in Tropical Countries","first-page":"178","article-title":"Parasitological tests","year":"2009"},{"key":"b39","series-title":"Guidelines for the Evaluation of Soil-Transmitted Helminthiasis and Schistosomiasis at Community Level: A Guide for Managers of Control Programmes","year":"1998"},{"key":"b40","series-title":"BMC Public Health","first-page":"1","article-title":"Prevalence and socio-demographic correlates of stunting and thinness among Pakistani primary school children","volume":"11","year":"2011"},{"key":"b41","series-title":"Lancet","first-page":"1478","article-title":"Population deworming every 6 months with albendazole in 1 million pre-school children in north India: DEVTA, a cluster-randomised trial","volume":"381","year":"2013"},{"key":"b42","series-title":"PLoS One","first-page":"e50325","article-title":"Impact of anthelminthic treatment in pregnancy and childhood on immunisations, infections and eczema in childhood: a randomised controlled trial","volume":"7","year":"2012"},{"key":"b43","series-title":"Am J Trop Med Hyg","first-page":"1478","article-title":"Effect of deworming on indices of health, cognition, and education among schoolchildren in rural China: a cluster-randomized controlled trial","volume":"96","year":"2017"},{"key":"b44","series-title":"J Nutr","first-page":"1320","article-title":"Vitamin A supplementation but not deworming improves growth of malnourished preschool children in eastern Zaire","volume":"128","year":"1998"},{"key":"b45","series-title":"Indian Pediatr","first-page":"19","article-title":"Effectiveness and cost-effectiveness of albendazole in improving nutritional status of pre-school children in urban slums","volume":"37","year":"2000"},{"key":"b46","series-title":"Trans R Soc Trop Med Hyg","first-page":"261","article-title":"Periodic deworming with albendazole and its impact on growth status and diarrhoeal incidence among children in an urban slum of India","volume":"99","year":"2005"},{"key":"b47","series-title":"J Parasitol Res","first-page":"4737891","article-title":"Soil-transmitted helminth reinfection and associated risk factors among school-age children in Chencha District, southern Ethiopia: a cross-sectional study","volume":"2016","year":"2016"},{"key":"b48","series-title":"Trop Med Health","first-page":"90","article-title":"Treatment efficacy and re-infection rates of soil-transmitted helminths following mebendazole treatment in schoolchildren, northwest Ethiopia","volume":"48","year":"2020"},{"key":"b49","series-title":"PLoS Negl Trop Dis","first-page":"e1621","article-title":"Soil-transmitted helminth reinfection after drug treatment: a systematic review and meta-analysis","volume":"6","year":"2012"},{"key":"b50","series-title":"PLoS One","first-page":"e0242744","article-title":"Spatial distribution and associated factors of underweight in Ethiopia: an analysis of Ethiopian demographic and health survey, 2016","volume":"15","year":"2020"},{"key":"b51","series-title":"BMC Nutr","first-page":"1","article-title":"Prevalence and associated factors of adolescent undernutrition in Ethiopia: a systematic review and meta-analysis","volume":"5","year":"2019"},{"key":"b52","series-title":"Cochrane Database Syst Rev","first-page":"CD000371","article-title":"Public health deworming programmes for soil-transmitted helminths in children living in endemic areas","volume":"9","year":"2019"},{"key":"b53","series-title":"Campbell Syst Rev","first-page":"1","article-title":"Deworming and adjuvant interventions for improving the developmental health and well\u2010being of children in low\u2010and middle\u2010income countries: a systematic review and network meta\u2010analysis","volume":"12","year":"2016"},{"key":"b54","series-title":"Am J Trop Med Hyg","first-page":"1478","article-title":"Effect of deworming on indices of health, cognition, and education among schoolchildren in rural China: a cluster-randomized controlled trial","volume":"96","year":"2017"},{"key":"b55","series-title":"PLoS Negl Trop Dis","first-page":"e331","article-title":"Diagnosis of soil-transmitted helminths in the era of preventive 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