{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,12,7]],"date-time":"2023-12-07T00:45:16Z","timestamp":1701909916762},"reference-count":29,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"6","license":[{"start":{"date-parts":[[2023,12,6]],"date-time":"2023-12-06T00:00:00Z","timestamp":1701820800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,12,6]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>Both SARS-CoV2 and <jats:italic>Plasmodium falciparum<\/jats:italic> infection during pregnancy increases the risk for adverse maternal and fetal outcomes, including abortion, severe disease, and death. Indeed, although malaria and COVID-19 show an overlapping clinical presentation, they require a profoundly different approach. The aim of this study was to explore COVID-19 awareness among pregnant women living in a <jats:italic>P. falciparum<\/jats:italic> hyperendemic region in rural Uganda. This cross-sectional, prospective study was conducted in one Hospital and two Health Centers (HC) in Lango region, Uganda, from July 14, 2022, to March 14, 2023. Data about demographics, COVID-19 history, and COVID-19 and malaria perceptions were collected using RedCap mobile app platform. Study endpoint was a context-specific COVID-19 awareness score, accounting for the most common disease misconceptions. Association between study variables and good COVID-19 awareness was assessed by \u03c7<jats:sup>2<\/jats:sup> and <jats:italic>t<\/jats:italic> test, as appropriate, and variables found to be statistically significant were further explored in multivariate logistic regression analysis. A total of 888 pregnant women were recruited. Median age was 24 (interquartile range: 20\u201329) years, whereas 79% (<jats:italic>n =<\/jats:italic> 704) attained only primary education and 66.6% (<jats:italic>n =<\/jats:italic> 591) were used in agriculture. SARS-CoV2 vaccination rate was 92%. In multivariate analysis (Table 3), variables associated with high COVID knowledge were presenting at antenatal care visit in Atipe HC (adjusted odds ratio [aOR]: 8.1, 95% CI: 4.1\u201316.48) having a previous good knowledge about malaria (aOR: 1.76, 95% CI: 1.21\u20132.56). Among pregnant women living in rural Uganda, COVID-19 awareness relies on the overall educational level, malaria knowledge and reference HC. Among pregnant women living in <jats:italic>P. falciparum<\/jats:italic> endemic areas, community-level malaria awareness might guide educational interventions during future pandemics.<\/jats:p>","DOI":"10.4269\/ajtmh.23-0464","type":"journal-article","created":{"date-parts":[[2023,11,6]],"date-time":"2023-11-06T18:57:23Z","timestamp":1699297043000},"page":"1363-1367","source":"Crossref","is-referenced-by-count":0,"title":["COVID Perceptions among Pregnant Women Living in a Malaria Hyperendemic Rural Region in Uganda: A Cross-Sectional Study"],"prefix":"10.4269","volume":"109","author":[{"given":"Francesco Vladimiro","family":"Segala","sequence":"first","affiliation":[{"name":"Clinic of Infectious Diseases, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari \u201cAldo Moro,\u201d Bari, Italy;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giulia","family":"Patti","sequence":"additional","affiliation":[{"name":"Clinic of Infectious Diseases, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari \u201cAldo Moro,\u201d Bari, Italy;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lameck","family":"Olal","sequence":"additional","affiliation":[{"name":"African Network for Change, Kampala, Uganda;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elda","family":"De Vita","sequence":"additional","affiliation":[{"name":"Clinic of Infectious Diseases, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari \u201cAldo Moro,\u201d Bari, Italy;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nelson","family":"Olung","sequence":"additional","affiliation":[{"name":"St. John\u2019s XXIII Hospital Aber, Jaber, Uganda;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberta","family":"Papagni","sequence":"additional","affiliation":[{"name":"Clinic of Infectious Diseases, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari \u201cAldo Moro,\u201d Bari, Italy;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James","family":"Amone","sequence":"additional","affiliation":[{"name":"St. John\u2019s XXIII Hospital Aber, Jaber, Uganda;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valentina","family":"Totaro","sequence":"additional","affiliation":[{"name":"Clinic of Infectious Diseases, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari \u201cAldo Moro,\u201d Bari, Italy;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emmanuel","family":"Onapa","sequence":"additional","affiliation":[{"name":"St. John\u2019s XXIII Hospital Aber, Jaber, Uganda;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberta","family":"Novara","sequence":"additional","affiliation":[{"name":"Clinic of Infectious Diseases, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari \u201cAldo Moro,\u201d Bari, Italy;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benedict","family":"Ngole","sequence":"additional","affiliation":[{"name":"African Network for Change, Kampala, Uganda;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariangela","family":"L\u2019Episcopia","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Istituto Superiore di Sanit\u00e0, Rome, Italy;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samuel","family":"Okori","sequence":"additional","affiliation":[{"name":"St. John\u2019s XXIII Hospital Aber, Jaber, Uganda;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanni","family":"Dall\u2019Oglio","sequence":"additional","affiliation":[{"name":"Doctors with Africa, CUAMM, Kampala, Uganda;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jerry","family":"Ictho","sequence":"additional","affiliation":[{"name":"Doctors with Africa, CUAMM, Kampala, Uganda;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlo","family":"Severini","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Istituto Superiore di Sanit\u00e0, Rome, Italy;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanni","family":"Putoto","sequence":"additional","affiliation":[{"name":"Operational Research Unit, Doctors with Africa CUAMM, Padua, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Lochoro","sequence":"additional","affiliation":[{"name":"Doctors with Africa, CUAMM, Kampala, Uganda;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Di Gennaro","sequence":"additional","affiliation":[{"name":"Clinic of Infectious Diseases, Department of 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