{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T06:44:50Z","timestamp":1790923490048,"version":"4.1.0"},"reference-count":10,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"1","license":[{"start":{"date-parts":[[2024,1,3]],"date-time":"2024-01-03T00:00:00Z","timestamp":1704240000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,1,3]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>In 2021, we treated three patients in Southern California who contracted malaria while traveling in Uganda. Two patients visited the Nile River in Uganda in the months of July and August 2021, and upon returning to the United States, diagnosis was delayed due to limited access to care during the COVID-19 pandemic. One of the patients developed severe malaria, and the second developed parasitemia after he stopped taking malaria prophylaxis. The third patient, who traveled to Kampala, Uganda, in December 2021 returned home and was admitted for chronic medical conditions. Later in the clinical course, he developed symptoms consistent with malaria, but due to SARS-CoV-2 diagnosis, there was no suspicion of malaria infection until it was incidentally discovered while performing a blood manual differential. All patients were treated for malaria and recovered uneventfully.<\/jats:p>","DOI":"10.4269\/ajtmh.23-0467","type":"journal-article","created":{"date-parts":[[2023,11,27]],"date-time":"2023-11-27T18:09:03Z","timestamp":1701108543000},"page":"64-68","source":"Crossref","is-referenced-by-count":2,"title":["Case Report: Challenges of Diagnosing Malaria in Returning Travelers at the Height of COVID-19 Pandemic"],"prefix":"10.4269","volume":"110","author":[{"given":"Edwin","family":"Kamau","sequence":"first","affiliation":[{"name":"Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California, Los Angeles, California;"},{"name":"Department of Pathology and Area Laboratory Services, Tripler Army Medical Center, Honolulu, Hawaii;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Olivo Freites","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, David Geffen School of Medicine, University of California, Los Angeles, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashlyn N.","family":"Sakona","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, David Geffen School of Medicine, University of California, Los Angeles, California"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"b1","series-title":"World Malaria Report","year":"2021"},{"key":"b2","series-title":"J Travel Med","first-page":"229","article-title":"Imported malaria in adults and children: epidemiological and clinical characteristics of 380 consecutive cases observed in Verona, Italy","volume":"15","author":"Mascarello","year":"2008"},{"key":"b3","series-title":"Clin Microbiol Rev","first-page":"e00104","article-title":"Imported malaria in countries where malaria is not endemic: a comparison of semi-immune and nonimmune travelers","volume":"33","author":"Mischlinger","year":"2020"},{"key":"b4","series-title":"J Travel Med","first-page":"317","article-title":"Imported malaria in immigrants to Italy: a changing pattern observed in north eastern Italy","volume":"16","author":"Mascarello","year":"2009"},{"key":"b5","series-title":"BMC Med","first-page":"22","article-title":"Antibody responses to merozoite antigens after natural Plasmodium falciparum infection: kinetics and longevity in absence of re-exposure","volume":"17","author":"Yman","year":"2019"},{"key":"b6","series-title":"Am J Trop Med Hyg","first-page":"501","article-title":"Use of qPCR and genomic sequencing to diagnose Plasmodium ovale wallikeri malaria in a returned soldier in the setting of a negative rapid diagnostic assay","volume":"89","author":"Cohen","year":"2013"},{"key":"b7","series-title":"Parasitology","first-page":"S95","article-title":"The biology of Plasmodium falciparum transmission stages","volume":"116","author":"Day","year":"1998"},{"key":"b8","series-title":"Clin Infect Dis","first-page":"704","article-title":"Malaria transmission dynamics in high transmission setting of western Kenya and the inadequate treatment response to artemether-lumefantrine in an asymptomatic population","volume":"76","author":"Andagalu","year":"2023"},{"key":"b9","series-title":"J Infect Dis","first-page":"146","article-title":"Safety and tolerability of mosquito bite-induced controlled human infection with Plasmodium vivax in malaria-naive study participants \u2013 clinical profile and utility of molecular diagnostic methods","volume":"225","author":"Kamau","year":"2022"},{"key":"b10","series-title":"Malar J","first-page":"58","article-title":"Mefloquine pharmacokinetics and mefloquine-artesunate effectiveness in Peruvian patients with uncomplicated Plasmodium falciparum malaria","volume":"8","author":"Gutman","year":"2009"}],"container-title":["The American Journal of Tropical 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Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/110\/1\/article-p64.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/110\/1\/article-p64.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/110\/1\/article-p64.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,3]],"date-time":"2024-01-03T18:15:25Z","timestamp":1704305725000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/110\/1\/article-p64.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1,3]]},"references-count":10,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.23-0467","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1,3]]}}}