{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,5,2]],"date-time":"2024-05-02T00:32:54Z","timestamp":1714609974459},"reference-count":57,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"5","license":[{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,5,1]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>In Uganda, women engaged in sex work (WESW) are a marginalized population at the intersection of multiple vulnerabilities. The Kyaterekera intervention is targeted at WESW in Rakai and the greater Masaka regions in Uganda and combines a traditional HIV risk-reduction approach with a savings-led economic empowerment intervention and financial literacy training. We estimated the economic costs of the Kyaterekera intervention from a program provider perspective using a prospective activity-based micro-costing method. All program activities and resource uses were measured and valued across the control arm receiving a traditional HIV risk-reduction intervention and the treatment arm receiving a matched individual development savings account and financial literacy training on top of HIV risk reduction. The total per-participant cost by arm was adjusted for inflation and discounted at an annual rate of 3% and presented in 2019 US dollars. The total per-participant costs of the control and intervention arms were estimated at $323 and $1,435, respectively, using the per-protocol sample. When calculated based on the intent-to-treat sample, the per-participant costs were reduced to $183 and $588, respectively. The key cost drivers were the capital invested in individual development accounts and personnel and transportation costs for program operations, linked to WESW\u2019s higher mobility and the dispersed pattern of hot spot locations. The findings provide evidence of the economic costs of implementing a targeted intervention for this marginalized population in resource-constrained settings and shed light on the scale of potential investment needed to better achieve the health equity goal of HIV prevention strategies.<\/jats:p>","DOI":"10.4269\/ajtmh.23-0485","type":"journal-article","created":{"date-parts":[[2024,4,2]],"date-time":"2024-04-02T15:14:23Z","timestamp":1712070863000},"page":"1046-1056","source":"Crossref","is-referenced-by-count":0,"title":["Costing of a Combination Intervention (Kyaterekera) Addressing Sexual Risk-Taking Behaviors among Vulnerable Women in Southern Uganda"],"prefix":"10.4269","volume":"110","author":[{"given":"Yesim","family":"Tozan","sequence":"first","affiliation":[{"name":"School of Global Public Health, New York University, New York, New 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Uganda;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edward","family":"Nsubuga","sequence":"additional","affiliation":[{"name":"Brown School, Washington University in St. Louis, St. Louis, Missouri;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatuma","family":"Nakabuye","sequence":"additional","affiliation":[{"name":"International Center for Child Health and Development, Masaka, Uganda;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ozge Bahar","family":"Sensoy","sequence":"additional","affiliation":[{"name":"Brown School, Washington University in St. Louis, St. Louis, Missouri;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Proscovia","family":"Nabunya","sequence":"additional","affiliation":[{"name":"Brown School, Washington University in St. Louis, St. Louis, Missouri;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Larissa 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DREAMS","volume":"13","author":"Ziraba","year":"2018"},{"key":"b12","series-title":"Afr Health Sci","first-page":"107","article-title":"Has the HIV\/AIDS epidemic changed sexual behaviour of high risk groups in Uganda?","volume":"3","author":"Ntozi","year":"2003"},{"key":"b13","series-title":"Public Health Rep","first-page":"9","article-title":"Addressing poverty as risk for disease: Recommendations from CDC\u2019s consultation on microenterprise as HIV prevention","volume":"123","author":"Stratford","year":"2008"},{"key":"b14","series-title":"AIDS Behav","first-page":"1","article-title":"Economic vulnerability, violence, and sexual risk factors for HIV among female sex workers in Tijuana, Mexico","volume":"26","author":"Reed","year":"2022"},{"key":"b15","series-title":"Lancet","first-page":"55","article-title":"Global epidemiology of HIV among female sex workers: Influence of structural determinants","volume":"385","author":"Shannon","year":"2015"},{"key":"b16","series-title":"AIDS Behav","first-page":"1","article-title":"Project Nova: A combination HIV prevention and microfinance intervention for women who engage in sex work and use drugs in Kazakhstan","volume":"23","author":"Mergenova","year":"2019"},{"key":"b17","series-title":"PLoS One","first-page":"e0226809","article-title":"Evaluation of a savings-led family-based economic empowerment intervention for AIDS-affected adolescents in Uganda: A four-year follow-up on efficacy and cost-effectiveness","volume":"14","author":"Tozan","year":"2019"},{"key":"b18","series-title":"Am J Public Health","first-page":"483","article-title":"Effect of economic assets on sexual risk-taking intentions among orphaned adolescents in Uganda","volume":"100","author":"Ssewamala","year":"2010"},{"key":"b19","series-title":"Am J Public Health","first-page":"e95","article-title":"Efficacy of a savings-led microfinance intervention to reduce sexual risk for HIV among women engaged in sex work: A randomized clinical trial","volume":"105","author":"Witte","year":"2015"},{"key":"b20","series-title":"AIDS Behav","first-page":"1785","article-title":"Reducing sexual HIV\/STI risk and harmful alcohol use among female sex workers in Mongolia: A randomized clinical trial","volume":"15","author":"Witte","year":"2011"},{"key":"b21","series-title":"J Prev Int Com","first-page":"89","article-title":"Sexual risk behaviors, alcohol abuse, and intimate partner violence among sex workers in Mongolia: Implications for HIV prevention intervention development","volume":"38","author":"Witte","year":"2010"},{"key":"b22","series-title":"Int J Environ Res Public Health","first-page":"14326","article-title":"Impact of family-based economic empowerment intervention, Suubi+Adherence (2012\u20132018) on multidimensional poverty for adolescents living with HIV (ALWHIV) in Uganda","volume":"19","author":"Dvalishvili","year":"2022"},{"key":"b23","series-title":"J Epidemiol Community 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A systematic review of economic empowerment as HIV prevention intervention for adolescent girls and young women in sub-Saharan Africa using the RE-AIM framework","volume":"1","author":"Iwelunmor","year":"2020"},{"key":"b25","series-title":"AIDS Care","first-page":"273","article-title":"Effect of savings-led economic empowerment on HIV preventive practices among orphaned adolescents in rural Uganda: Results from the Suubi-Maka randomized experiment","volume":"28","author":"Jennings","year":"2016"},{"key":"b26","series-title":"Soc Sci Med","first-page":"191","article-title":"Asset ownership and health and mental health functioning among AIDS-orphaned adolescents: Findings from a randomized clinical trial in rural Uganda","volume":"69","author":"Ssewamala","year":"2009"},{"key":"b27","series-title":"J Adolesc Health","first-page":"372","article-title":"Gender and the effects of an economic empowerment program on attitudes toward sexual risk-taking among AIDS-orphaned adolescent youth in Uganda","volume":"46","author":"Ssewamala","year":"2010"},{"key":"b28","series-title":"J Adolesc Health","first-page":"S29","article-title":"Cost-effectiveness of a savings-led economic empowerment intervention for AIDS-affected adolescents in Uganda: Implications for scale-up in low-resource communities","volume":"62","author":"Ssewamala","year":"2018"},{"key":"b29","series-title":"BMC Womens Health","first-page":"1","article-title":"A combination intervention addressing sexual risk-taking behaviors among vulnerable women in Uganda: Study protocol for a cluster randomized clinical trial","volume":"19","author":"Ssewamala","year":"2019"},{"key":"b30","year":"2013"},{"key":"b31","year":"2017"},{"key":"b32","series-title":"Hist Afr","first-page":"301","article-title":"The historiography of HIV and AIDS in Uganda","volume":"35","author":"Kuhanen","year":"2008"},{"key":"b33","author":"Ssembatya","year":"2015"},{"key":"b34","series-title":"Lancet","first-page":"2062","article-title":"Uganda begins distributing free antiretrovirals. If the plan succeeds, Uganda will be on track to meet WHO\u2019s 3 by 5 target for antiretroviral treatment","volume":"363","author":"Wendo","year":"2004"},{"key":"b35","series-title":"AIDS Behav","first-page":"1004","article-title":"Self-reported adherence to antiretroviral therapy (ART) among women engaged in commercial sex work in southern Uganda","volume":"27","author":"Kiyingi","year":"2023"},{"key":"b36","year":"2016"},{"key":"b37","series-title":"Asian J Soc Psychol","first-page":"21","article-title":"Social cognitive theory: An agentic perspective","volume":"2","author":"Bandura","year":"1999"},{"key":"b38","year":"2002"},{"key":"b39","series-title":"Proc Natl Acad Sci USA","first-page":"10575","article-title":"Behavioral economics: Reunifying psychology and economics","volume":"96","author":"Camerer","year":"1999"},{"key":"b40","series-title":"Methods for the Economic Evaluation of Health Care 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population","volume":"1","author":"Remple","year":"2007"},{"key":"b47","series-title":"Am J Trop Med Hyg","first-page":"1078","article-title":"Costing of a multiple family group strengthening intervention (SMART-Africa) to improve child and adolescent behavioral health in Uganda","volume":"106","author":"Tozan","year":"2022"},{"key":"b48","series-title":"Cost-Effectiveness Analysis Improving Parenting Practices in Liberia and Thailand","year":"2016"},{"key":"b49","series-title":"BMJ Glob Health","first-page":"e001147","article-title":"Cost and cost-effectiveness of a parenting programme to prevent violence against adolescents in South Africa","volume":"4","author":"Redfern","year":"2019"},{"key":"b50","series-title":"Nat Commun","first-page":"976","article-title":"Migration, hotspots, and dispersal of HIV infection in Rakai, Uganda","volume":"11","author":"Grabowski","year":"2020"},{"key":"b51","series-title":"JAMA","first-page":"1093","article-title":"Recommendations for conduct, 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