{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,3]],"date-time":"2025-04-03T15:03:29Z","timestamp":1743692609377},"reference-count":33,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,4,3]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>The aim of this study was to analyze postsurgical outcomes for individuals with mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE-HS) who underwent anterior temporal lobectomy, based on the presence of calcified neurocysticercosis (cNCC). A retrospective cross-sectional study was conducted on 89 patients with MTLE-HS who underwent anterior temporal lobectomy between January 2012 and December 2020 at a basic epilepsy surgery center located in Lima, Peru. We collected sociodemographic, clinical, and diagnostic information. The postsurgical results were analyzed using bivariate analysis according to the Engel classification. We included 89 individuals with a median age of 28\u2009years (interquartile range [IQR]: 24\u201337), and more than half (55.1%) were male. Seventeen (19.1%) were diagnosed with cNCC. A greater number of patients with cNCC had lived in rural areas of Peru during their early life compared with those without cNCC (12 [70.6%] versus 26 [36.1%]; <jats:italic>P<\/jats:italic> = 0.010). Patients with cNCC exhibited a greater median frequency of focal to bilateral tonic-clonic seizures per month (1 [IQR: 0\u20132] versus 0 [0\u20130.5]; <jats:italic>P<\/jats:italic> = 0.009). Conversely, a lower proportion of patients with cNCC reported a history of an initial precipitating injury in comparison to the group without cNCC (4 [23.5%] versus 42 [58.3%]; <jats:italic>P<\/jats:italic> = 0.014). At the 1-year follow-up, most patients (82.4%) with cNCC were categorized as Engel IA. Similarly, at the 2-year follow-up, nine (75.0%) were classified as Engel IA. Our findings suggest that most patients diagnosed with cNCC exhibit favorable postsurgical outcomes, comparable to those without cNCC. Additionally, it can be postulated that cNCC may play a role as an initial precipitating injury.<\/jats:p>","DOI":"10.4269\/ajtmh.23-0506","type":"journal-article","created":{"date-parts":[[2024,3,5]],"date-time":"2024-03-05T19:29:07Z","timestamp":1709666947000},"page":"700-705","source":"Crossref","is-referenced-by-count":1,"title":["Postsurgical Outcomes of Mesial Temporal Lobe Epilepsy due to Hippocampal Sclerosis Associated with Calcified Neurocysticercosis"],"prefix":"10.4269","volume":"110","author":[{"given":"Walter","family":"De la Cruz","sequence":"first","affiliation":[{"name":"Epilepsy Department, Instituto Nacional de Ciencias Neurol\u00f3gicas, Lima, Peru;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sof\u00eda S.","family":"S\u00e1nchez-Boluarte","sequence":"additional","affiliation":[{"name":"Epilepsy Department, Instituto Nacional de Ciencias Neurol\u00f3gicas, Lima, Peru;"},{"name":"School of Medicine, Universidad Cesar Vallejo, Trujillo, Peru;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Denisse E.","family":"Chac\u00f3n","sequence":"additional","affiliation":[{"name":"Epilepsy Department, Instituto Nacional de Ciencias Neurol\u00f3gicas, Lima, Peru;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuel","family":"Herrera","sequence":"additional","affiliation":[{"name":"Department of Medicine, McMaster University, Hamilton, Ontario, Canada;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liza","family":"N\u00fa\u00f1ez del Prado","sequence":"additional","affiliation":[{"name":"Epilepsy Department, Instituto Nacional de Ciencias Neurol\u00f3gicas, Lima, Peru;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos M.","family":"V\u00e1squez","sequence":"additional","affiliation":[{"name":"Neurosurgery Department, Instituto Nacional de Ciencias Neurol\u00f3gicas, Lima, Peru"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 C.","family":"Delgado","sequence":"additional","affiliation":[{"name":"Epilepsy Department, Instituto Nacional de Ciencias Neurol\u00f3gicas, Lima, Peru;"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"b1","series-title":"Neuroscientist","first-page":"340","article-title":"Mesial temporal lobe epilepsy: what have we learned?","volume":"7","author":"Engel","year":"2001"},{"key":"b2","series-title":"Epilepsia","first-page":"20","article-title":"Mesial temporal lobe epilepsy with hippocampal sclerosis","volume":"45","author":"Wieser","year":"2004"},{"key":"b3","series-title":"JAMA","first-page":"285","article-title":"Resective epilepsy surgery for drug-resistant focal epilepsy: a review","volume":"313","author":"Jobst","year":"2015"},{"key":"b4","series-title":"Neurology","first-page":"1669","article-title":"Systematic review and meta-analysis of standard vs selective temporal lobe epilepsy 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