{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T07:26:02Z","timestamp":1790925962984,"version":"4.1.0"},"reference-count":51,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,12,4]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>Schistosomiasis is a global public health challenge, especially in sub-Saharan Africa, where Nigeria has the highest burden of disease. <jats:italic>Schistosoma<\/jats:italic> hybrids have been discovered in various countries, including Nigeria, where livestock and human beings share common water resources. This study, carried out in three communities, two of which are endemic for urinary schistosomiasis, aimed to identify the urinary schistosomiasis causative agent by using a species-specific molecular technique and their evolutionary relationship. Polymerase chain reaction using primers specific for a partial DNA sequence of the mitochondrial <jats:italic>cox1<\/jats:italic> gene of <jats:italic>Schistosoma haematobium<\/jats:italic> was carried out on pooled urine sediments preserved in 70% ethanol. DNA from the high-intensity pooled samples from Onye-Uku camp amplified, and a BLAST search identified the pooled samples as <jats:italic>Schistosoma bovis<\/jats:italic>, whereas <jats:italic>S. haematobium<\/jats:italic> DNA did not amplify. The phylogenetic relationship of the sequence showed that it clustered with an <jats:italic>S. bovis<\/jats:italic> hybrid obtained from a human host in C\u00f4te d\u2019Ivoire and had close ancestry with isolates from cattle in Cameroon. This finding revealed the prevalence of <jats:italic>S. bovis<\/jats:italic> among some inhabitants in a zone in Nigeria where schistosomiasis is endemic.<\/jats:p>","DOI":"10.4269\/ajtmh.23-0539","type":"journal-article","created":{"date-parts":[[2024,10,15]],"date-time":"2024-10-15T15:57:23Z","timestamp":1729007843000},"page":"1230-1236","source":"Crossref","is-referenced-by-count":4,"title":["Human Schistosomiasis due to Schistosoma bovis in Nigeria"],"prefix":"10.4269","volume":"111","author":[{"given":"Antonia Omenebele","family":"Enudi","sequence":"first","affiliation":[{"name":"Department of Fisheries, Ministry of Agriculture and Natural Resources, Asaba, Nigeria;"},{"name":"Department of Animal and Environmental Biology, Faculty of Science, Delta State University, Abraka, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Onyebiguwa Patrick Goddey","family":"Nmorsi","sequence":"additional","affiliation":[{"name":"Department of Animal and Environmental Biology, Faculty of Science, Delta State University, Abraka, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andy Ogochukwu","family":"Egwunyenga","sequence":"additional","affiliation":[{"name":"Department of Animal and Environmental Biology, Faculty of Science, Delta State University, Abraka, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"b1","series-title":"Guideline on Control and Elimination of Human Schistosomiasis","year":"2022"},{"key":"b2","series-title":"Southeast Asian J Trop Med Public Health","first-page":"32","article-title":"Urinary tract pathology in Schistosoma haematobium infected rural Nigerians","volume":"38","author":"Nmorsi","year":"2007"},{"key":"b3","series-title":"PLoS Negl Trop Dis","first-page":"e1882","article-title":"Genetic diversity within Schistosoma haematobium: DNA barcoding reveals two distinct 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