{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T07:44:24Z","timestamp":1781077464489,"version":"3.54.1"},"reference-count":17,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,3,6]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>Rickettsial diseases cover a broad spectrum of illnesses. Scrub typhus is present worldwide, and <jats:italic>Orientia tsutsugamushi<\/jats:italic> is the causative agent of this chigger mite\u2013borne infectious illness. Infections exhibit a range of severity, from mild illness to the more severe manifestation of multiorgan failure. We report three cases of scrub fever (55-year-old female, 63-year-old female, and 29-year-old male), all cases developed focal or pan-digital gangrene. All cases were successfully treated by administering doxycycline and additional supportive measures. Digital gangrene is uncommon in scrub typhus. Clinical suspension for early diagnosis and appropriate treatment may avoid further complications.<\/jats:p>","DOI":"10.4269\/ajtmh.23-0596","type":"journal-article","created":{"date-parts":[[2024,2,13]],"date-time":"2024-02-13T20:51:32Z","timestamp":1707857492000},"page":"497-500","source":"Crossref","is-referenced-by-count":3,"title":["Digital Gangrene Associated with Scrub Typhus: A Case Series"],"prefix":"10.4269","volume":"110","author":[{"given":"Jitendra","family":"Singh","sequence":"first","affiliation":[{"name":"Department of General Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anju","family":"Dinkar","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India;"},{"name":"Department of Microbiology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nilesh","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of General Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kailash","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of General Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nidhi","family":"Tejan","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"b1","series-title":"J Indian Acad Clin Med","first-page":"187","article-title":"Digital gangrene: a rare complication in scrub 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literature","volume":"8","author":"Panagopoulos","year":"2014"},{"key":"b17","series-title":"J Clin Diagn Res","first-page":"OD03","article-title":"Meningitis with digital gangrene in meningococcal infection: an atypical presentation","volume":"10","author":"Singh","year":"2016"}],"container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/110\/3\/article-p497.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/110\/3\/article-p497.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/110\/3\/article-p497.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,6]],"date-time":"2024-03-06T13:55:48Z","timestamp":1709733348000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/110\/3\/article-p497.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,6]]},"references-count":17,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.23-0596","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3,6]]}}}