{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T03:34:45Z","timestamp":1793504085689,"version":"4.5.0"},"reference-count":0,"publisher":"American Society of Tropical Medicine and Hygiene","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,8,6]]},"abstract":"<jats:p>Leptospirosis, a bacterial infection transmitted through contact with infected animals or contaminated water sources, imposes a substantial health burden in Colombia. Since 2007, the National Institute of Health (INS) has mandated the notification and confirmation of all suspected leptospirosis cases. This passive surveillance program employs the microscopic agglutination test (MAT) on serum samples to ascertain confirmed cases of leptospirosis infection. However, the absence of a robust surveillance system has hindered our comprehensive understanding of the morbidity, mortality, geographical distribution, species\/serovars, and strains responsible for severe disease. Our study aimed to provide an epidemiological overview of MAT-confirmed human leptospirosis cases reported over 6 years (2015\u20132020) in Colombia. In addition, we offer insights into the status of leptospirosis in the country, focusing on risk factors and proposing potential improvements for diagnosis and disease management. During the 6-year surveillance period, the laboratory at the INS received 3,535 serum samples from suspected human leptospirosis cases, with 880 (25%) confirmed through MAT. The incidence of leptospirosis was calculated at 1.9 cases per 100,000 people, with a higher prevalence among men (82.1%). Furthermore, 54 (6.1%) deaths were confirmed as leptospirosis, and cases were documented across nearly all regions of Colombia. Our findings emphasize the urgent need to strengthen leptospirosis laboratory surveillance, implement effective prevention measures, and enhance diagnostic capabilities in Colombia. The analysis conducted in this study provides the groundwork for estimating the impact of leptospirosis and raises awareness of its significance in public health.<\/jats:p>","DOI":"10.4269\/ajtmh.23-0654","type":"journal-article","created":{"date-parts":[[2024,8,6]],"date-time":"2024-08-06T09:42:53Z","timestamp":1722937373000},"source":"Crossref","is-referenced-by-count":4,"title":["Serologically Confirmed Human Leptospirosis in Colombia, 2015\u20132020"],"prefix":"10.4269","author":[{"given":"Eliana L.","family":"Parra-Barrera","sequence":"first","affiliation":[{"name":"Facultad de Medicina, Pontificia Universidad Cat\u00f3lica de Chile, Santiago, Chile;"},{"name":"Multidisciplinary Initiative for Collaborative Research on Bacterial Resistance (MICROB-R), Santiago, Chile;"},{"name":"Clinical Studies and Clinical Epidemiology Division, Fundaci\u00f3n Santa Fe de Bogot\u00e1, Bogot\u00e1, Colombia;"},{"name":"Grupo de Microbiolog\u00eda, Instituto Nacional de Salud, Bogot\u00e1, Colombia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Solmara","family":"Bello-Piruccini","sequence":"additional","affiliation":[{"name":"Grupo de Microbiolog\u00eda, Instituto Nacional de Salud, Bogot\u00e1, Colombia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karina","family":"Rodr\u00edguez","sequence":"additional","affiliation":[{"name":"Grupo de Microbiolog\u00eda, Instituto Nacional de Salud, Bogot\u00e1, Colombia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina","family":"Duarte-Valderrama","sequence":"additional","affiliation":[{"name":"Grupo de Microbiolog\u00eda, Instituto Nacional de Salud, Bogot\u00e1, Colombia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marisa","family":"Torres","sequence":"additional","affiliation":[{"name":"Facultad de Medicina, Pontificia Universidad Cat\u00f3lica de Chile, Santiago, Chile;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo A.","family":"Undurraga","sequence":"additional","affiliation":[{"name":"Multidisciplinary Initiative for Collaborative Research on Bacterial Resistance (MICROB-R), Santiago, Chile;"},{"name":"Escuela de Gobierno, Pontificia Universidad Cat\u00f3lica de Chile, Santiago, Chile;"},{"name":"The Canadian Institute for Advanced Research Azrieli Global Scholars Program, CIFAR, Toronto, Canada;"},{"name":"Research Center for Integrated Disaster Risk Management (CIGIDEN), Santiago, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/aop\/article-10.4269-ajtmh.23-0654\/article-10.4269-ajtmh.23-0654.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/aop\/article-10.4269-ajtmh.23-0654\/article-10.4269-ajtmh.23-0654.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/aop\/article-10.4269-ajtmh.23-0654\/article-10.4269-ajtmh.23-0654.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,6]],"date-time":"2024-08-06T09:42:54Z","timestamp":1722937374000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/aop\/article-10.4269-ajtmh.23-0654\/article-10.4269-ajtmh.23-0654.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,6]]},"references-count":0,"URL":"https:\/\/doi.org\/10.4269\/ajtmh.23-0654","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,8,6]]}}}