{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T23:14:36Z","timestamp":1790810076271,"version":"4.1.0"},"reference-count":38,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,9,4]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p><jats:italic>Deinagkistrodon acutus<\/jats:italic> envenomation is one of the most common types of venomous snakebite in China and causes a series of envenomating effects on its victims. However, more specific information on the characteristics of <jats:italic>D. acutus<\/jats:italic> envenomation is rare in the English literature. Therefore, we aimed to give a detailed description of the epidemiological and clinical features of patients with <jats:italic>D. acutus<\/jats:italic> envenomation. Patients who were admitted with <jats:italic>D. acutus<\/jats:italic> envenomation between January 2018 and December 2021 were enrolled in this retrospective study. The data on demographics, clinical manifestations, laboratory features, management, and outcomes were collected. A total of 158 cases of <jats:italic>D. acutus<\/jats:italic> envenomation were enrolled. Men (<jats:italic>n<\/jats:italic> = 121; 76.6%) and rural populations (<jats:italic>n<\/jats:italic> = 133; 84.2%) were the high-risk groups, and most incidents (<jats:italic>n<\/jats:italic> = 141; 89.2%) happened between May and September. The specific effect was tissue necrosis at bite site, which occurred in 72 patients (45.6%). Other envenomation effects include extensive limb swelling, blistering, wound bleeding, and coagulopathy. In the envenomed patients, 155 (98.1%) received antivenom, 47 (29.7%) needed operations, 20 (12.7%) required intensive care, and one died. <jats:italic>Deinagkistrodon acutus<\/jats:italic> envenomation is a common snakebites emergency in Hangzhou area. A high rate of tissue necrosis at bite site and venom-induced consumption coagulopathy are the characteristics of <jats:italic>D. acutus<\/jats:italic> envenomation. Although the mortality rate is low, some patients still require intensive care.<\/jats:p>","DOI":"10.4269\/ajtmh.23-0680","type":"journal-article","created":{"date-parts":[[2024,7,2]],"date-time":"2024-07-02T13:16:44Z","timestamp":1719926204000},"page":"676-681","source":"Crossref","is-referenced-by-count":9,"title":["The Epidemiology and Clinical Features of Deinagkistrodon acutus Envenomation: A Retrospective Study from a Medical Center in Hangzhou, Southeast China"],"prefix":"10.4269","volume":"111","author":[{"given":"Sipin","family":"Hu","sequence":"first","affiliation":[{"name":"The Second Clinical Medical College of Zhejiang Chinese Medical University, Hangzhou, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuhua","family":"Bao","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory, Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuchen","family":"Shen","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengyun","family":"Tu","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory, Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"b1","series-title":"Trans R Soc Trop Med Hyg","first-page":"287","article-title":"Clinical characteristics of snakebite patients attending a tertiary hospital in Hangzhou, southeast China","volume":"118","author":"Shen","year":"2023"},{"key":"b2","series-title":"Am J Trop Med Hyg","first-page":"925","article-title":"Bacteriological studies of venomous snakebite wounds in Hangzhou, 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