{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T17:49:37Z","timestamp":1789148977209,"version":"build-2803163510"},"reference-count":13,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,6,5]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p><jats:italic>Parthenium hysterophorus<\/jats:italic> is the commonest cause of plant dermatitis in India. It classically causes airborne contact dermatitis (ABCD), characterized by pruritic, eczematous, and lichenified lesions involving predominantly the face and flexural areas. Over time, however, a transition to chronic actinic dermatitis (CAD) pattern, with prominent involvement of sun-exposed sites, may occur. Management involves strict protective measures and topical and oral corticosteroids or immunomodulatory agents but often leads to only limited success. We report a patient with a chronic and extensive mixed ABCD-CAD pattern of parthenium dermatitis recalcitrant to conventional treatment, with rapid resolution after initiation of treatment with tofacitinib.<\/jats:p>","DOI":"10.4269\/ajtmh.23-0720","type":"journal-article","created":{"date-parts":[[2024,4,16]],"date-time":"2024-04-16T19:28:10Z","timestamp":1713295690000},"page":"1276-1278","source":"Crossref","is-referenced-by-count":2,"title":["Case Report: Mixed Airborne Contact Dermatitis\u2013Chronic Actinic Dermatitis Pattern of Parthenium Dermatitis with Response to Tofacitinib Therapy"],"prefix":"10.4269","volume":"110","author":[{"given":"Ananta","family":"Khurana","sequence":"first","affiliation":[{"name":"Department of Dermatology, Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheetal","family":"Yadav","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kunal","family":"Chanana","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kabir","family":"Sardana","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aakash","family":"Vidholiya","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"b1","series-title":"Australas J Dermatol","first-page":"e1","article-title":"Photo-patch and patch tests in patients with dermatitis over the photo-exposed areas: A study of 101 cases from a tertiary care centre in India","volume":"59","author":"Sharma","year":"2018"},{"key":"b2","series-title":"Handbook of Eczema for Dermatologists","author":"Khurana"},{"key":"b3"},{"key":"b4","series-title":"Indian Dermatol Online J","first-page":"89","article-title":"Parthenium the terminator: An update","volume":"3","author":"Lakshmi","year":"2009"},{"key":"b5","series-title":"Chem Rec","first-page":"258","article-title":"\u03b1\u2010Methylene\u2010\u03b3\u2010butyrolactones: Versatile skin bioactive natural products","volume":"9","author":"Lepoittevin","year":"2009"},{"key":"b6","series-title":"Photochem Photobiol Sci","first-page":"85","article-title":"Parthenium dermatitis","volume":"12","author":"Sharma","year":"2013"},{"key":"b7","series-title":"Dermatitis","first-page":"147","article-title":"Chronic actinic dermatitis: An analysis at a single institution over 25 years","volume":"22","author":"Que","year":"2011"},{"key":"b8","series-title":"Dermatol Clin","first-page":"355","article-title":"Chronic actinic dermatitis","volume":"32","author":"Paek","year":"2014"},{"key":"b9","series-title":"Contact Dermat","first-page":"150","article-title":"Tofacitinib in refractory Parthenium-induced airborne allergic contact dermatitis","volume":"88","author":"Muddebihal","year":"2023"},{"key":"b10","series-title":"JAAD Case Rep","first-page":"4","article-title":"Tofacitinib citrate for the treatment of refractory, severe chronic actinic dermatitis","volume":"3","author":"Vesely","year":"2016"},{"key":"b11","series-title":"Indian J Dermatol Venereol Leprol","first-page":"600","article-title":"Recalcitrant chronic actinic dermatitis responding to tofacitinib: A case report","volume":"89","author":"Dev","year":"2023"},{"key":"b12","series-title":"Pediatr Dermatol","first-page":"139","article-title":"Use of tofacitinib in baricitinib-refractory atopic dermatitis: An example of JAK inhibitor switching","volume":"41","author":"Dhir","year":"2023"},{"key":"b13","series-title":"J Dermatolog Treat","first-page":"2873","article-title":"Tofacitinib in the treatment of refractory eczemas: A case series","volume":"33","author":"Duraisamy","year":"2022"}],"container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/110\/6\/article-p1276.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/110\/6\/article-p1276.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/110\/6\/article-p1276.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,5]],"date-time":"2024-06-05T12:59:23Z","timestamp":1717592363000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/110\/6\/article-p1276.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,5]]},"references-count":13,"journal-issue":{"issue":"6"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.23-0720","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6,5]]}}}