{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T03:09:59Z","timestamp":1790478599684,"version":"4.1.0"},"reference-count":31,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,12,4]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Streptococcus suis<\/jats:italic>\n                    is the most common and severe cause of meningitis in Vietnam, but the recent data about epidemiological characteristics and sequelae are still inadequate. We performed a retrospective study to describe the epidemiology, clinical characteristics, and outcomes of patients with\n                    <jats:italic>S. suis<\/jats:italic>\n                    -associated meningitis. A retrospective study was carried out by searching records from the Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam, between January 2016 and January 2020. All data concerning epidemiological, clinical, and subclinical characteristics and treatment results were collected and analyzed. Over the study period, 153 cases were included in this study, with 95 cases occurring in the 2016\u20132017 period. The median age of all patients was 52 years (range, 29\u201390 years), and 70.6% of patients were male. Fifty-two patients (34%) were farmers, and the Mekong Delta was the region with the highest number of cases (60.1%). The most frequent manifestation of infection was fever (151\/153, 98.7%), followed by hearing loss (64\/153, 41.8%), and one patient (0.7%) died. All isolates remained susceptible to ceftriaxone, penicillin, vancomycin, and levofloxacin, whereas 99.2% of isolates were resistant to tetracycline. Occupational exposure to pigs and the consumption of contaminated food have been identified as primary risk factors associated with this zoonosis, and our study found no significant changes in epidemiological factors compared with past data. The Mekong Delta continues to be the most affected region for\n                    <jats:italic>S. suis<\/jats:italic>\n                    meningitis in southern Vietnam, with\n                    <jats:italic>S. suis<\/jats:italic>\n                    serotype 2 remaining the most relevant agent.\n                  <\/jats:p>","DOI":"10.4269\/ajtmh.23-0774","type":"journal-article","created":{"date-parts":[[2024,10,15]],"date-time":"2024-10-15T11:56:49Z","timestamp":1728993409000},"page":"1247-1251","source":"Crossref","is-referenced-by-count":8,"title":["Streptococcus suis-Associated Meningitis in a Southern Region of Vietnam"],"prefix":"10.4269","volume":"111","author":[{"given":"Nguyen Huu","family":"Thanh","sequence":"first","affiliation":[{"name":"School of Medicine, Vietnam National University, Ho Chi Minh City, Vietnam;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doan Thanh","family":"Huy","sequence":"additional","affiliation":[{"name":"School of Medicine, Vietnam National University, Ho Chi Minh City, Vietnam;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vo Thi Tram","family":"Anh","sequence":"additional","affiliation":[{"name":"School of Medicine, Vietnam National University, Ho Chi Minh City, Vietnam;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nguyen Ngoc","family":"Anh","sequence":"additional","affiliation":[{"name":"School of Medicine, Vietnam National University, Ho Chi Minh City, Vietnam;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nguyen Thi Thu","family":"Uyen","sequence":"additional","affiliation":[{"name":"School of Medicine, Vietnam National University, Ho Chi Minh City, Vietnam;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nguyen Ho Hong","family":"Hanh","sequence":"additional","affiliation":[{"name":"School of Medicine, Vietnam National University, Ho Chi Minh City, Vietnam;"},{"name":"Department of Infectious Disease, Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nguyen Hoan","family":"Phu","sequence":"additional","affiliation":[{"name":"School of Medicine, Vietnam National University, Ho Chi Minh City, Vietnam;"},{"name":"Department of Infectious Disease, Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"b1","series-title":"Clin Infect Dis","first-page":"617","article-title":"Streptococcus suis: An emerging human pathogen","volume":"48","author":"Werthelm","year":"2009"},{"key":"b2","year":"2013"},{"key":"b3","series-title":"Emerg Infect Dis","first-page":"914","article-title":"Human Streptococcus suis outbreak, Sichuan, China","volume":"12","author":"Yu","year":"2006"},{"key":"b4","series-title":"Microb Genom","first-page":"mgen000952","article-title":"Streptococcus suis outbreak caused by an emerging zoonotic strain with acquired multi-drug resistance in Thailand","volume":"9","author":"Brizuela","year":"2023"},{"key":"b5","series-title":"Clin Infect Dis","first-page":"659","article-title":"Streptococcus suis meningitis in adults in Vietnam","volume":"46","author":"Mai","year":"2008"},{"key":"b6","series-title":"PLoS One","first-page":"e17604","article-title":"Risk factors of Streptococcus suis infection in Vietnam. 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