{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,8]],"date-time":"2026-11-08T21:03:45Z","timestamp":1794171825406,"version":"4.8.0"},"reference-count":23,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,6,5]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>For the past two decades, Bangladesh has faced recurrent dengue outbreaks, with the most recent occurring in 2023. We investigated the socioeconomic, clinical, and laboratory aspects of patients diagnosed with dengue during this outbreak. This observational study was conducted from July to September 2023 at Dhaka Medical College Hospital and Chittagong Medical College Hospital, and included 450 confirmed cases of dengue. Sociodemographic information was collected via face-to-face interviews, clinical examinations, and laboratory testing, which was done within 24 hours of admission. Dengue severity was classified according to the 2009 WHO dengue guidelines. Notably, 17% of patients experienced severe dengue, and 89% of those with nonsevere cases exhibited at least one warning sign. Most patients were young adults (mean age, 33 years), with a nearly equal male-to-female ratio. Common clinical presentations included fever (95%), myalgia (62%), and headache (58%), whereas warning signs such as vomiting (54%) and abdominal pain (39%) were prevalent. Plasma leakage indicators, including ascites, pleural effusion, and edema, were found predominantly in severe cases. Laboratory findings revealed leukopenia, thrombocytopenia, and elevated hepatic enzymes (alanine aminotransferase and aspartate aminotransferase) in nearly half the patients. An elevated hematocrit level was associated with severe dengue. We report that a substantial number of patients developed severe dengue during the epidemic in 2023, and provide detailed clinical\u2013epidemiological profiles of the patients, offering valuable insight into management of dengue cases.<\/jats:p>","DOI":"10.4269\/ajtmh.23-0806","type":"journal-article","created":{"date-parts":[[2024,4,9]],"date-time":"2024-04-09T17:46:47Z","timestamp":1712684807000},"page":"1165-1171","source":"Crossref","is-referenced-by-count":13,"title":["The 2023 Dengue Outbreak in Bangladesh: Exploring the Epidemiology in Hospitalized Patients"],"prefix":"10.4269","volume":"110","author":[{"given":"Urby Saraf","family":"Anika","sequence":"first","affiliation":[{"name":"Public Health and Research, Tropical Disease and Health Research Center, Dhaka, Bangladesh;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muna","family":"Islam","sequence":"additional","affiliation":[{"name":"Department of Medicine, Chittagong Medical College Hospital, Chattogram, Bangladesh;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatema E Nur","family":"Mou","sequence":"additional","affiliation":[{"name":"Department of Radiology and Imaging, Mugda Medical College Hospital, Dhaka, Bangladesh;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mrinal","family":"Saha","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, Chittagong Medical College Hospital, Chattogram, Bangladesh;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aparna","family":"Deb","sequence":"additional","affiliation":[{"name":"Department of Medicine, Chittagong Medical College Hospital, Chattogram, Bangladesh;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rubaiya Rahman","family":"Tui","sequence":"additional","affiliation":[{"name":"Department of Medicine, Dhaka Medical College Hospital, Dhaka, Bangladesh;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joarder Rakeen","family":"Manzoor","sequence":"additional","affiliation":[{"name":"Department of Medicine, Dhaka Medical College Hospital, Dhaka, Bangladesh;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Afroza","family":"Jesmin","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venerology, Mugda Medical College Hospital, Dhaka, Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayesha","family":"Martuja","sequence":"additional","affiliation":[{"name":"Department of Medicine, Chittagong Medical College Hospital, Chattogram, Bangladesh;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jannatul","family":"Fardous","sequence":"additional","affiliation":[{"name":"Public Health and Research, Tropical Disease and Health Research Center, Dhaka, Bangladesh;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohiuddin","family":"Sharif","sequence":"additional","affiliation":[{"name":"Public Health and Research, Tropical Disease and Health Research Center, Dhaka, Bangladesh;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Md. Abdur","family":"Rafi","sequence":"additional","affiliation":[{"name":"Public Health and Research, Tropical Disease and Health Research Center, Dhaka, Bangladesh;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad Jahid","family":"Hasan","sequence":"additional","affiliation":[{"name":"Public Health and Research, Tropical Disease and Health Research Center, Dhaka, Bangladesh;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"b1","series-title":"J Travel Med","first-page":"taab146","article-title":"Global burden for dengue and the evolving pattern in the past 30 years","volume":"28","author":"Yang","year":"2021"},{"key":"b2","series-title":"Nat Microbiol","first-page":"1508","article-title":"The current and future global distribution and population at risk of dengue","volume":"4","author":"Messina","year":"2019"},{"key":"b3","series-title":"Lancet Infect Dis","first-page":"712","article-title":"The global burden of dengue: 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