{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T20:00:04Z","timestamp":1789243204585,"version":"build-2803163510"},"reference-count":50,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"1","license":[{"start":{"date-parts":[[2024,7,3]],"date-time":"2024-07-03T00:00:00Z","timestamp":1719964800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,7,3]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p><jats:italic>Acinetobacter baumannii<\/jats:italic> (<jats:italic>Ab<\/jats:italic>) is a well-known nosocomial pathogen that has emerged as a cause of community-acquired pneumonia (CAP) in tropical regions. Few global epidemiological studies of CAP<jats:italic>-Ab<\/jats:italic> have been published to date, and no data are available on this disease in France. We conducted a retrospective chart review of severe cases of CAP-<jats:italic>Ab<\/jats:italic> admitted to intensive care units in R\u00e9union University Hospital between October 2014 and October 2022. Eight severe CAP<jats:italic>-<\/jats:italic>Ab cases were reviewed. Median patient age was 56.5 years. Sex ratio (male-to-female) was 3:1. Six cases (75.0%) occurred during the rainy season. Chronic alcohol use and smoking were found in 75.0% and 87.5% of cases, respectively. All patients presented in septic shock and with severe acute respiratory distress syndrome. Seven patients (87.5%) presented in cardiogenic shock, and renal replacement therapy was required for six patients (75.0%). Five cases (62.5%) presented with bacteremic pneumonia. The mortality rate was 62.5%. The median time from hospital admission to death was 3 days. All patients received inappropriate initial antibiotic therapy<jats:italic>. Acinetobacter baumannii<\/jats:italic> isolates were all susceptible to ceftazidime, cefepime, piperacillin-tazobactam, ciprofloxacin, gentamicin, and imipenem. Six isolates (75%) were also susceptible to ticarcillin, piperacillin, and cotrimoxazole. Severe CAP-<jats:italic>Ab<\/jats:italic> has a fulminant course and high mortality. A typical case is a middle-aged man with smoking and chronic alcohol use living in a tropical region and developing severe CAP during the rainy season. This clinical presentation should prompt administration of antibiotic therapy targeting <jats:italic>Ab<\/jats:italic>.<\/jats:p>","DOI":"10.4269\/ajtmh.23-0820","type":"journal-article","created":{"date-parts":[[2024,6,4]],"date-time":"2024-06-04T15:33:05Z","timestamp":1717515185000},"page":"136-140","source":"Crossref","is-referenced-by-count":10,"title":["Case Report: Severe Community-Acquired Pneumonia in R\u00e9union Island due to Acinetobacter baumannii"],"prefix":"10.4269","volume":"111","author":[{"given":"Giacomo","family":"Rotini","sequence":"first","affiliation":[{"name":"Department of Intensive Care Medicine, Felix Guyon University Hospital, Saint-Denis, France;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Axel","family":"de Mangou","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Medicine, Felix Guyon University Hospital, Saint-Denis, France;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agathe","family":"Combe","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Medicine, Felix Guyon University Hospital, Saint-Denis, France;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julien","family":"Jabot","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Medicine, Felix Guyon University Hospital, Saint-Denis, France;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B\u00e9r\u00e9nice","family":"Puech","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Medicine, Felix Guyon University Hospital, Saint-Denis, France;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurence","family":"Dangers","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Medicine, Felix Guyon University Hospital, Saint-Denis, France;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathilde","family":"Nativel","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Medicine, Felix Guyon University Hospital, Saint-Denis, France;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Allou","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Medicine, Felix Guyon University Hospital, Saint-Denis, France;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillaume","family":"Miltgen","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Felix Guyon University Hospital, Saint-Denis, France;"},{"name":"UMR PIMIT, CNRS 9192, INSERM U1187, IRD 249, University of Reunion, Saint-Clotilde, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles","family":"Vidal","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Medicine, Felix Guyon University Hospital, Saint-Denis, France;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"b1","series-title":"Curr Opin Infect Dis","first-page":"69","article-title":"Managing Acinetobacter baumannii infections","volume":"32","author":"Garnacho-Montero","year":"2019"},{"key":"b2","series-title":"Clin Microbiol Rev","first-page":"538","article-title":"Acinetobacter baumannii: Emergence of a successful pathogen","volume":"21","author":"Peleg","year":"2008"},{"key":"b3","series-title":"Crit Care","first-page":"134","article-title":"Attributable mortality of Acinetobacter baumannii: No longer a controversial issue","volume":"11","author":"Falagas","year":"2007"},{"key":"b4","series-title":"Expert Rev Anti Infect Ther","first-page":"567","article-title":"Community-acquired Acinetobacter baumannii: Clinical characteristics, epidemiology and 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