{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T05:51:07Z","timestamp":1777528267332,"version":"3.51.4"},"reference-count":22,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,6,5]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>We explored the association between serological status for hepatitis E and neurocysticercosis (NCC) in neurologic patients attending a national neurological referral center in Lima, Per\u00fa, between the years 2008 and 2012. Anti-hepatitis E antibodies were evaluated in patients with and without NCC, and a control group of rural general population. Anti-hepatitis E IgG was found in 23.8% of patients with NCC, compared with 14.3% in subjects without NCC from a general rural population (<jats:italic>P =<\/jats:italic> 0.023) and 14.4% in subjects with neurological complaints without NCC (<jats:italic>P =<\/jats:italic> 0.027). Seropositive patients had a median age of 44\u2009years compared with 30\u2009years in seronegative patients (<jats:italic>P<\/jats:italic> &lt;0.001). No significant differences in sex, region of residence, or liver enzyme values were found. Seropositivity to hepatitis E was frequent in this Peruvian population and higher in patients with NCC, suggesting shared common routes of infection.<\/jats:p>","DOI":"10.4269\/ajtmh.23-0856","type":"journal-article","created":{"date-parts":[[2024,4,23]],"date-time":"2024-04-23T14:43:17Z","timestamp":1713883397000},"page":"1210-1213","source":"Crossref","is-referenced-by-count":1,"title":["Increased Prevalence of Antibodies to Hepatitis E Virus in Patients with Neurocysticercosis"],"prefix":"10.4269","volume":"110","author":[{"given":"Jesus","family":"Abanto","sequence":"first","affiliation":[{"name":"Centro de Salud Global, Universidad Peruana Cayetano Heredia, Lima, Per\u00fa;"},{"name":"Department of Neurology, University of Cincinnati, Cincinnati, Ohio;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arantxa N.","family":"Sanchez Boluarte","sequence":"additional","affiliation":[{"name":"Facultad de Medicina, Universidad Peruana Cayetano Heredia, Lima, Per\u00fa;"},{"name":"Department of Global Health, University of Washington, Seattle, Washington;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yesenia","family":"Castillo","sequence":"additional","affiliation":[{"name":"Centro de Salud Global, Universidad Peruana Cayetano Heredia, Lima, Per\u00fa;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erika","family":"Perez","sequence":"additional","affiliation":[{"name":"Centro B\u00e1sico de Investigaci\u00f3n en Ex\u00e1menes Auxiliares en Parasitosis del Sistema Nervioso Central, Instituto Nacional de Ciencias Neurol\u00f3gicas, Lima, Per\u00fa;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Herbert","family":"Saavedra","sequence":"additional","affiliation":[{"name":"Centro B\u00e1sico de Investigaci\u00f3n en Ex\u00e1menes Auxiliares en Parasitosis del Sistema Nervioso Central, Instituto Nacional de Ciencias Neurol\u00f3gicas, Lima, Per\u00fa;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isidro","family":"Gonzales","sequence":"additional","affiliation":[{"name":"Centro B\u00e1sico de Investigaci\u00f3n en Ex\u00e1menes Auxiliares en Parasitosis del Sistema Nervioso Central, Instituto Nacional de Ciencias Neurol\u00f3gicas, Lima, Per\u00fa;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Javier A.","family":"Bustos","sequence":"additional","affiliation":[{"name":"Centro de Salud Global, Universidad Peruana Cayetano Heredia, Lima, Per\u00fa;"},{"name":"Centro B\u00e1sico de Investigaci\u00f3n en Ex\u00e1menes Auxiliares en Parasitosis del Sistema Nervioso Central, Instituto Nacional de Ciencias Neurol\u00f3gicas, Lima, Per\u00fa;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Florence","family":"Abravanel","sequence":"additional","affiliation":[{"name":"Laboratoire de Virologie, CHU Purpan, Toulouse, France;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacques","family":"Izopet","sequence":"additional","affiliation":[{"name":"Laboratoire de Virologie, CHU Purpan, Toulouse, France;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richie G.","family":"Madden","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Royal Adelaide Hospital, University of Adelaide, South Australia;"},{"name":"HEV International Direct Action Group (HEViDrAG)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hector H.","family":"Garcia","sequence":"additional","affiliation":[{"name":"Centro de Salud Global, Universidad Peruana Cayetano Heredia, Lima, Per\u00fa;"},{"name":"Centro B\u00e1sico de Investigaci\u00f3n en Ex\u00e1menes Auxiliares en Parasitosis del Sistema Nervioso Central, Instituto Nacional de Ciencias Neurol\u00f3gicas, Lima, Per\u00fa;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harry R.","family":"Dalton","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Royal Adelaide Hospital, University of Adelaide, South Australia;"},{"name":"HEV International Direct Action Group (HEViDrAG)"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"b1","series-title":"J Clin Transl Hepatol","first-page":"376","article-title":"Hepatitis E: A literature review","volume":"5","author":"Guerra","year":"2017"},{"key":"b2","series-title":"Nat Rev Dis Primers","first-page":"17086","article-title":"Hepatitis E virus infection","volume":"3","author":"Kamar","year":"2017"},{"key":"b3","series-title":"J Clin Virol Off Publ Pan Am Soc Clin Virol","first-page":"20","article-title":"Hepatitis E virus infections in 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Paulo, southeastern Brazil: Analysis of a group of blood donors representative of the general population","volume":"21","author":"Passos-Castilho","year":"2017"},{"key":"b19","series-title":"Am J Trop Med Hyg","first-page":"1275","article-title":"Seroprevalence of hepatitis A virus, hepatitis E virus, and Helicobacter pylori in rural communities of the Bolivian Chaco, 2013","volume":"98","author":"Campolmi","year":"2018"},{"key":"b20","series-title":"Eur J Gastroenterol Hepatol","first-page":"215","article-title":"Investigation of liver dysfunction: Who should we test for hepatitis E?","volume":"29","author":"Wallace","year":"2017"},{"key":"b21","series-title":"Am J Case Rep","first-page":"584","article-title":"A case report about the most common yet most forgotten hepatitis E","volume":"17","author":"Chandnani","year":"2016"},{"key":"b22","series-title":"Indian J Med Res","first-page":"64","article-title":"Role of acute viral hepatitis as a confounding factor in antituberculosis treatment induced hepatotoxicity","volume":"129","author":"Sarda","year":"2009"}],"container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/110\/6\/article-p1210.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/110\/6\/article-p1210.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/110\/6\/article-p1210.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,5]],"date-time":"2024-06-05T13:04:52Z","timestamp":1717592692000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/110\/6\/article-p1210.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,5]]},"references-count":22,"journal-issue":{"issue":"6"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.23-0856","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6,5]]}}}