{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,5]],"date-time":"2024-09-05T00:30:01Z","timestamp":1725496201987},"reference-count":14,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,9,4]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>Leprosy reactions are complex immune events, generating disabling consequences and threatening the lives of those who experience them. This case report addresses the episode of a 28-year-old female patient who suffered a severe type-2 leprosy reaction, characterized by significant hepatic involvement, specifically, nonalcoholic hepatic steatosis. This case report underscores the importance of maintaining a high level of clinical suspicion, early recognition, accurate diagnosis, and immediate addressing of these types of reactions that may arise in the context of leprosy.<\/jats:p>","DOI":"10.4269\/ajtmh.23-0874","type":"journal-article","created":{"date-parts":[[2024,7,2]],"date-time":"2024-07-02T13:16:31Z","timestamp":1719926191000},"page":"560-564","source":"Crossref","is-referenced-by-count":0,"title":["Case Report: Nonalcoholic Hepatic Steatosis Associated with Type-2 Leprosy Reaction"],"prefix":"10.4269","volume":"111","author":[{"given":"Karina Lucia","family":"Araujo Orozco","sequence":"first","affiliation":[{"name":"Servicio de Infectolog\u00eda, IMAT ONCOMEDICA Auna, Monter\u00eda, Columbia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johan Sebasti\u00e1n","family":"Prada Cubillos","sequence":"additional","affiliation":[{"name":"Servicio de Medicina General, IMAT ONCOMEDICA Auna, Monter\u00eda, Colombia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda Jos\u00e9","family":"Otero Genes","sequence":"additional","affiliation":[{"name":"Servicio de Medicina General, IMAT ONCOMEDICA Auna, Monter\u00eda, Colombia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H\u00e9ctor","family":"Serrano-Coll","sequence":"additional","affiliation":[{"name":"Instituto Colombiano de Medicina Tropical, Universidad CES, Medell\u00edn, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mara Judith","family":"Garc\u00eda Posada","sequence":"additional","affiliation":[{"name":"Servicio de Infectolog\u00eda, IMAT ONCOMEDICA Auna, Monter\u00eda, Columbia;"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"b1","series-title":"Emerg Infect Dis","first-page":"1067","article-title":"Mycobacterium lepromatosis as cause of leprosy, Colombia","volume":"28","author":"Cardona-Castro","year":"2022"},{"key":"b2","series-title":"J Trop Med","first-page":"8652062","article-title":"Leprosy: A review of epidemiology, clinical diagnosis, and management","volume":"2022","author":"Chen","year":"2022"},{"key":"b3","series-title":"Bull World Health Organ","first-page":"451","article-title":"Histological classification and the immunological spectrum of leprosy","volume":"51","author":"Ridley","year":"1974"},{"key":"b4","series-title":"Trans R Soc Trop Med Hyg","first-page":"125","article-title":"Anti-natural octyl disaccharide-leprosy IDRI diagnostic (NDO-LID) antibodies as indicators of leprosy reactions and neuritis","volume":"111","author":"Serrano-Coll","year":"2017"},{"key":"b5","series-title":"Infect Dis Poverty","first-page":"5","article-title":"The influence of innate and adaptive immune responses on the differential clinical outcomes of leprosy","volume":"6","author":"de Lima Fonseca","year":"2017"},{"key":"b6","series-title":"Indian J Dermatol Venereol Leprol","first-page":"464","article-title":"Lucio\u2019s phenomenon: A systematic literature review of definition, clinical features, histopathogenesis and management","volume":"88","author":"Frade","year":"2022"},{"key":"b7","series-title":"Front Med","first-page":"865485","article-title":"Leprosy reactions and neuropathic pain in pure neural leprosy in a reference center in Rio de Janeiro - 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