{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,3]],"date-time":"2025-04-03T04:13:20Z","timestamp":1743653600120,"version":"3.40.3"},"reference-count":8,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"4_Suppl","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,4,1]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>Congregate settings are high-risk places for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission, making strategies that rely solely on hospital-based testing ineffective in curbing transmissions. We therefore evaluated the feasibility, utility, and acceptability of testing with SARS-CoV-2 antigen rapid diagnostic tests (Ag-RDTs) in markets and trade hubs in Kampala, Uganda. Between June and September 2022, we conducted a prospective operational research study in five divisions of Kampala. Four rounds of monthly cross-sectional surveys were conducted at one market and one trading hub per division, resulting in a total of 13,086 volunteers tested. Females were more likely than males to be tested (54% versus 46%), which aligns with sex-based differences in health-seeking behavior. More tests were conducted in markets (68%) compared with trade centers (32%). Several interventions increased overall demand for testing, including 1) awareness campaigns and mobilization activities; 2) the movement of teams across congregate settings; 3) the optimization of workflow; and 4) testing traders at their workstations. The overall positivity rate during the 4 months was 0.6% (78\/13,086). There was a steady decline in positivity rates by month, aligning with the trend observed at the national level. Of the 78 positive index cases identified, 105 contacts were traced; 71% of these could be reached. None of the positive patients successfully self-isolated for the 14 days specified in national guidelines. Nevertheless, this study demonstrates that testing market dwellers with Ag-RDTs is not only acceptable and feasible in Uganda but also an important public health tool for the timely detection of SARS-CoV-2. This approach may be replicated in similar settings.<\/jats:p>","DOI":"10.4269\/ajtmh.23-0899","type":"journal-article","created":{"date-parts":[[2025,2,25]],"date-time":"2025-02-25T21:42:21Z","timestamp":1740519741000},"page":"79-83","source":"Crossref","is-referenced-by-count":0,"title":["Feasibility and Acceptability of SARS-CoV-2 Antigen Rapid Diagnostic Testing in High-Risk Markets and Trade Hubs in Kampala, Uganda"],"prefix":"10.4269","volume":"112","author":[{"given":"Isaac","family":"Ssewanyana","sequence":"first","affiliation":[{"name":"Central Public Health Laboratory, Ministry of Health, Kampala, Uganda;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sam","family":"Acellam","sequence":"additional","affiliation":[{"name":"Central Public Health Laboratory, Ministry of Health, Kampala, Uganda;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martha","family":"Ampumuza","sequence":"additional","affiliation":[{"name":"Central Public Health Laboratory, Ministry of Health, Kampala, Uganda;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hellen","family":"Nansumba","sequence":"additional","affiliation":[{"name":"Central Public Health Laboratory, Ministry of Health, Kampala, Uganda;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan","family":"Nabadda","sequence":"additional","affiliation":[{"name":"Central Public Health Laboratory, Ministry of Health, Kampala, Uganda;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Grace","family":"Kushemererwa","sequence":"additional","affiliation":[{"name":"Central Public Health Laboratory, Ministry of Health, Kampala, Uganda;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victor","family":"Bigira","sequence":"additional","affiliation":[{"name":"Central Public Health Laboratory, Ministry of Health, Kampala, Uganda;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah","family":"Zalwango","sequence":"additional","affiliation":[{"name":"Kampala Capital City Authority, Kampala, Uganda;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chris","family":"Oundo","sequence":"additional","affiliation":[{"name":"Kampala Capital City Authority, Kampala, Uganda;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"Walyomo","sequence":"additional","affiliation":[{"name":"Kampala Capital City Authority, Kampala, Uganda;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isaiah","family":"Chebrot","sequence":"additional","affiliation":[{"name":"Kampala Capital City Authority, Kampala, Uganda;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dennis Mike","family":"Buluma","sequence":"additional","affiliation":[{"name":"Kampala Capital City Authority, Kampala, Uganda;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alex","family":"Ndyabakira","sequence":"additional","affiliation":[{"name":"Kampala Capital City Authority, Kampala, Uganda;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pallavi","family":"Dani","sequence":"additional","affiliation":[{"name":"FIND, Geneva, Switzerland;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne","family":"Hoppe","sequence":"additional","affiliation":[{"name":"FIND, Geneva, Switzerland;"},{"name":"Elizabeth Glaser Pediatric AIDS Foundation, Geneva, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"series-title":"WHO Coronavirus (COVID-19) Dashboard","key":"b1"},{"series-title":"COVID-19 Response Info Hub","key":"b2"},{"year":"2020","series-title":"Guidelines for Prevention of COVID-19 in Market Places","key":"b3"},{"year":"2020","series-title":"Socio-economic Impact of COVID-19 in Uganda: Short-, Medium-, and Long Term Impacts on Poverty Dynamics and SDGs Using Scenario Analysis and System Dynamics Modeling","key":"b4"},{"series-title":"World Population Day Celebrations. Leveraging Uganda\u2019s Population Dynamics for a Resilient Future Amidst COVID-19, July 2020","key":"b5"},{"year":"2021","series-title":"Guidelines on COVID-19 Self-quarantine","key":"b6"},{"series-title":"Knight Frank Kampala Market Performance Review, July 2022","key":"b7"},{"key":"b8","series-title":"BMJ Leader","first-page":"113","article-title":"Managing enduring public health emergencies such as COVID-19: Lessons from Uganda Red Cross Society\u2019s Ebola virus disease response operation","volume":"4","author":"Geiger","year":"2020"}],"container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/112\/4_Suppl\/article-p79.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/112\/4_Suppl\/article-p79.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/112\/4_Suppl\/article-p79.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,2]],"date-time":"2025-04-02T13:25:23Z","timestamp":1743600323000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/112\/4_Suppl\/article-p79.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,1]]},"references-count":8,"journal-issue":{"issue":"4_Suppl"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.23-0899","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"type":"print","value":"0002-9637"},{"type":"electronic","value":"1476-1645"}],"subject":[],"published":{"date-parts":[[2025,4,1]]}}}