{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,20]],"date-time":"2025-06-20T12:48:13Z","timestamp":1750423693122,"version":"3.28.0"},"reference-count":13,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,11,6]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>Cutaneous leishmaniasis (CL) is classified as one of the skin-related neglected tropical diseases by the WHO. There have been limited reports of CL in C\u00f4te d\u2019Ivoire, with fewer than 20 cases reported from C\u00f4te d\u2019Ivoire in the literature since 1967, when it was first identified. Here, we report a case of CL originating in C\u00f4te d\u2019Ivoire that we diagnosed during our active case finding activity in the Zounan Hounien District. The patient, a 15-year-old male, presented with multiple noninflammatory skin lesions on the face and trunk that had progressed from nodular to ulcerated lesions over the previous 3 months. Concurrent symptoms included fever, chest pain, cough, and malaise. Investigations for infectious diseases such as HIV and tuberculosis returned negative results. Histopathological analysis of a skin biopsy specimen from the nasal base demonstrated the presence of Leishman-Donovan bodies, confirming a diagnosis of CL. Although treatment with intralesional meglumine antimoniate (Glucantime) injections was intended, the drug could not be administered because the patient unfortunately died shortly after our consultation visit. Because of the rarity of CL in C\u00f4te d\u2019Ivoire, awareness remains low, resulting in delayed diagnosis and treatment. Urgent strategies to improve awareness of CL among clinicians practicing in C\u00f4te d\u2019Ivoire is required, first to appropriately diagnose and treat CL and second to generate epidemiological data of adequate quality.<\/jats:p>","DOI":"10.4269\/ajtmh.23-0900","type":"journal-article","created":{"date-parts":[[2024,9,18]],"date-time":"2024-09-18T13:32:18Z","timestamp":1726666338000},"page":"950-952","source":"Crossref","is-referenced-by-count":1,"title":["Case Report: Cutaneous Leishmaniasis\u2014A Hidden Disease in C\u00f4te d\u2019Ivoire"],"prefix":"10.4269","volume":"111","author":[{"given":"Almamy","family":"Diabat\u00e9","sequence":"first","affiliation":[{"name":"Department of Dermatology, Universit\u00e9 Alassane Ouattara, Service de Dermatologie CHU de Bouak\u00e9-C\u00f4te d\u2019Ivoire, Bouak\u00e9, C\u00f4te d\u2019Ivoire;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryo","family":"Fukaura","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chiaki","family":"Terashima-Murase","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bamba","family":"Vagamon","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Universit\u00e9 Alassane Ouattara, Service de Dermatologie CHU de Bouak\u00e9-C\u00f4te d\u2019Ivoire, Bouak\u00e9, C\u00f4te d\u2019Ivoire;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rie R.","family":"Yotsu","sequence":"additional","affiliation":[{"name":"Department of Tropical Medicine, Tulane School of Public Health and Tropical Medicine, New Orleans, Louisiana;"},{"name":"School of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, Japan;"},{"name":"Department of Dermatology, National Center for Global Health and Medicine, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"b1"},{"key":"b2","series-title":"PLoS Negl Trop Dis","first-page":"e0011357","article-title":"A global call for action to tackle skin-related neglected tropical diseases (skin NTDs) through integration: An ambitious step change","volume":"17","author":"Yotsu","year":"2023"},{"key":"b3","series-title":"PLoS Negl Trop Dis","first-page":"e0006489","article-title":"Skin disease prevalence study in schoolchildren in rural C\u00f4te d\u2019Ivoire: Implications for integration of neglected skin diseases (skin NTDs)","volume":"12","author":"Yotsu","year":"2018"},{"key":"b4","series-title":"J Parasitol Res","first-page":"9282690","article-title":"Visceral leishmaniasis in West Africa: Clinical characteristics, vectors, and reservoirs","volume":"2019","author":"Kone","year":"2019"},{"key":"b5","series-title":"Rev Med C\u00f4te d\u2019Ivoire","first-page":"82","article-title":"Premi\u00e8re observation de la leishmaniose cutan\u00e9e en C\u00f4te-d\u2019Ivoire","volume":"3","author":"H\u00e9rouin","year":"1967"},{"key":"b6","series-title":"Rev Med C\u00f4te d\u2019Ivoire","first-page":"32","article-title":"A propos de 3 cas de leishmaniose cutan\u00e9e humaine diagnostiqu\u00e9s au laboratoire de parasitologie (CHU de Cocody-Abidjan)","volume":"18","author":"Ouhon","year":"1984"},{"key":"b7","series-title":"Eur Sci J","first-page":"224","article-title":"Diversite phlebotomienne dans trois villages de la Commune de Bouake (C\u00f4te d\u2019Ivoire) durant la periode de Mars a Juin 2019","volume":"16","author":"Nad\u00e8ge","year":"2020"},{"key":"b8","series-title":"Int Schol J","first-page":"1","article-title":"A case report of an imported cutaneous leishmaniasis in Cote d\u2019Ivoire","volume":"8","author":"Aka","year":"2021"},{"key":"b9","series-title":"Open Parasitol J","first-page":"1","article-title":"Pediatric cutaneous leishmaniasis in a private clinic of Abidjan, Ivory Coast: A case report","volume":"9","author":"Aka","year":"2021"},{"key":"b10","series-title":"JMIR Res Protoc","first-page":"e39867","article-title":"The early detection and case management of skin diseases with an mHealth app (eSkinHealth): Protocol for a mixed methods pilot study in C\u00f4te d\u2019Ivoire","volume":"11","author":"Yotsu","year":"2022"},{"key":"b11","series-title":"Glob Health Action","first-page":"4","article-title":"An outbreak of suspected cutaneous leishmaniasis in Ghana: Lessons learnt and preparation for future outbreaks","volume":"2011","author":"Kweku","year":"2011"},{"key":"b12","series-title":"Br J Dermatol","first-page":"157","article-title":"World Health Organization strategic framework for integrated control and management of skin-related neglected tropical diseases: What does this mean for dermatologists?","volume":"188","author":"Yotsu","year":"2023"},{"key":"b13","series-title":"JAMA Dermatol","first-page":"1032","article-title":"Incidence of endemic human cutaneous leishmaniasis in the United States","volume":"154","author":"McIlwee","year":"2018"}],"container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/111\/5\/article-p950.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/111\/5\/article-p950.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/111\/5\/article-p950.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,6]],"date-time":"2024-11-06T13:46:24Z","timestamp":1730900784000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/111\/5\/article-p950.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,6]]},"references-count":13,"journal-issue":{"issue":"5"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.23-0900","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"type":"print","value":"0002-9637"},{"type":"electronic","value":"1476-1645"}],"subject":[],"published":{"date-parts":[[2024,11,6]]}}}