{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T19:50:10Z","timestamp":1780516210076,"version":"3.54.1"},"reference-count":0,"publisher":"American Society of Tropical Medicine and Hygiene","license":[{"start":{"date-parts":[[2024,7,30]],"date-time":"2024-07-30T00:00:00Z","timestamp":1722297600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,7,30]]},"abstract":"<jats:p>Providing and improving the care of patients suffering from lymphedema remains an essential goal for the clinical management of populations affected by lymphatic filariasis. Although the Essential Package of Care (EPC) recommended by the WHO leads to important positive benefits for many of these lymphedema patients, it is important to continue to address the challenges that remain both in quantifying these effects and in ensuring optimal care. This report, based on the authors\u2019 scientific and field experience, focuses on the impact and significance of lymphedema, its clinical presentation, current treatment approaches, and the importance of lymphedema care to the Global Program to Eliminate Lymphatic Filariasis. It emphasizes specific practical issues related to managing lymphedema, such as the importance of beginning treatment in the condition\u2019s early stages and the development of effective approaches to assess patients\u2019 progress toward improving both their clinical status and their overall quality of life. Priorities for research are also examined, particularly the need for tools to identify patients and to assess disease burden in endemic communities, the creation of EPC accessibility to as many patients as possible (<jats:italic>i.e.<\/jats:italic>, targeting 100% \u201cgeographic coverage\u201d of care), and the empowerment of patients to ensure the sustainability, and ultimately the provision of care from sectors of the national public health systems of endemic countries.<\/jats:p>","DOI":"10.4269\/ajtmh.23-0905","type":"journal-article","created":{"date-parts":[[2024,7,30]],"date-time":"2024-07-30T13:58:30Z","timestamp":1722347910000},"source":"Crossref","is-referenced-by-count":6,"title":["Managing Lymphedema Induced by Lymphatic Filariasis: Implementing and Improving Care at the Individual and Programmatic Levels"],"prefix":"10.4269","author":[{"given":"Charles D.","family":"Mackenzie","sequence":"first","affiliation":[{"name":"Coalition for Operational Research on Neglected Tropical Diseases (COR-NTD), Task Force for Global Health, Atlanta, Georgia;"},{"name":"The END Fund, New York, New York;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D Ramaiah","family":"Kapa","sequence":"additional","affiliation":[{"name":"Consultant Lymphatic Filariasis Epidemiologist, Pondicherry, India;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suma","family":"Krishnasastry","sequence":"additional","affiliation":[{"name":"Filariasis Research Unit, WHO Collaborating Center for LF MMDP, Government T. D. Medical College Hospital, Kerala University of Health Sciences, Alappuzha, India;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Douglass","sequence":"additional","affiliation":[{"name":"Division of Tropical Health and Medicine, James Cook University, Townsville, Australia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Achim","family":"Hoerauf","sequence":"additional","affiliation":[{"name":"Institute for Medical Microbiology, Immunology and Parasitology, University Hospital of Bonn, Bonn, Germany;"},{"name":"German Center for Infection Research (DZIF), Partner Site Bonn-Cologne, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric A.","family":"Ottesen","sequence":"additional","affiliation":[{"name":"Coalition for Operational Research on Neglected Tropical Diseases (COR-NTD), Task Force for Global Health, Atlanta, Georgia;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/aop\/article-10.4269-ajtmh.23-0905\/article-10.4269-ajtmh.23-0905.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/aop\/article-10.4269-ajtmh.23-0905\/article-10.4269-ajtmh.23-0905.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/aop\/article-10.4269-ajtmh.23-0905\/article-10.4269-ajtmh.23-0905.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,30]],"date-time":"2024-07-30T13:58:30Z","timestamp":1722347910000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/aop\/article-10.4269-ajtmh.23-0905\/article-10.4269-ajtmh.23-0905.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,30]]},"references-count":0,"URL":"https:\/\/doi.org\/10.4269\/ajtmh.23-0905","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7,30]]}}}