{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T12:37:40Z","timestamp":1764333460911},"reference-count":0,"publisher":"American Society of Tropical Medicine and Hygiene","license":[{"start":{"date-parts":[[2024,7,23]],"date-time":"2024-07-23T00:00:00Z","timestamp":1721692800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,7,23]]},"abstract":"<jats:p>Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne viral disease with a mortality rate reaching up to 40% in humans. Currently, CCHF affects three continents: Asia, Europe, and Africa. An increase in confirmed cases in Africa has been observed since 2000. In Central Africa, several countries have reported the circulation of CCHV virus (CCHFV). However, in Gabon, there is a lack of recent data on the circulation of the virus in the Gabonese population. To provide an overview of the epidemiological situation in Gabon, we tested 3,081 human serum samples collected between 2005 and 2008 in villages throughout the country for anti-CCHFV antibodies. Using a double-antigen ELISA kit, our study found 15\/3,081 samples positive for CCHFV. These positive samples were also tested using the Blackbox CCHFV IgG kit and the Luminex technique. These analyses confirmed seven and four positives for the Blackbox CCHFV IgG kit and the Luminex technique, respectively. This study suggests low circulation of CCHFV in the rural human population of Gabon. Competent authorities must survey CCHFV to identify and prevent clinical cases in the human population.<\/jats:p>","DOI":"10.4269\/ajtmh.24-0054","type":"journal-article","created":{"date-parts":[[2024,7,23]],"date-time":"2024-07-23T21:10:03Z","timestamp":1721769003000},"source":"Crossref","is-referenced-by-count":1,"title":["First Detection of Antibodies Specific to Crimean-Congo Hemorrhagic Fever Virus in Rural Populations of Gabon"],"prefix":"10.4269","author":[{"given":"Linda","family":"Bohou Kombila","sequence":"first","affiliation":[{"name":"D\u00e9partement de Virologie, Unit\u00e9 Emergence des Maladies Virales, Centre Interdisciplinaire de Recherches M\u00e9dicales de Franceville, Franceville, Gabon;"},{"name":"Ecole Doctorale R\u00e9gionale d\u2019Afrique Centrale en Infectiologie Tropicale, Universit\u00e9 des Sciences et Techniques de Masuku, Franceville, Gabon;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sol\u00e8ne","family":"Lerolle","sequence":"additional","affiliation":[{"name":"Centre International de Recherche en Infectiologie, Universit\u00e9 de Lyon, Universit\u00e9 Claude Bernard Lyon 1, l\u2019Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale, U1111, Centre National de la Recherche Scientifique, UMR5308 \u00c9cole Normale Sup\u00e9rieure de Lyon, Lyon, France;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Illich Manfred","family":"Mombo","sequence":"additional","affiliation":[{"name":"D\u00e9partement de Virologie, Unit\u00e9 Emergence des Maladies Virales, Centre Interdisciplinaire de Recherches M\u00e9dicales de Franceville, Franceville, Gabon;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neil-Michel","family":"Longo-Pendy","sequence":"additional","affiliation":[{"name":"Unit\u00e9 de Recherche en Ecologie de la Sant\u00e9, Centre Interdisciplinaire de Recherches M\u00e9dicales de Franceville, Franceville, Gabon;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danielle","family":"Koumba Mavoungou","sequence":"additional","affiliation":[{"name":"D\u00e9partement de Virologie, Unit\u00e9 Emergence des Maladies Virales, Centre Interdisciplinaire de Recherches M\u00e9dicales de Franceville, Franceville, Gabon;"},{"name":"Ecole Doctorale R\u00e9gionale d\u2019Afrique Centrale en Infectiologie Tropicale, Universit\u00e9 des Sciences et Techniques de Masuku, Franceville, Gabon;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ga\u00ebl Darren","family":"Maganga","sequence":"additional","affiliation":[{"name":"D\u00e9partement de Virologie, Unit\u00e9 Emergence des Maladies Virales, Centre Interdisciplinaire de Recherches M\u00e9dicales de Franceville, Franceville, Gabon;"},{"name":"Institut National Sup\u00e9rieur d\u2019Agronomie et de Biotechnologies, Universit\u00e9 des Sciences et Techniques de Masuku, Franceville, Gabon;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francois-Lo\u00efc","family":"Cosset","sequence":"additional","affiliation":[{"name":"Centre International de Recherche en Infectiologie, Universit\u00e9 de Lyon, Universit\u00e9 Claude Bernard Lyon 1, l\u2019Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale, U1111, Centre National de la Recherche Scientifique, UMR5308 \u00c9cole Normale Sup\u00e9rieure de Lyon, Lyon, France;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jessica","family":"Vanhomwegen","sequence":"additional","affiliation":[{"name":"Cellule d\u2019Intervention Biologique d\u2019Urgence, Institut Pasteur de Paris, Paris, France;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christina","family":"Deschermeier","sequence":"additional","affiliation":[{"name":"Panadea Diagnostics GmbH, Hamburg, Germany;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric Maurice","family":"Leroy","sequence":"additional","affiliation":[{"name":"Maladies Infectieuses et Vecteurs, Ecologie, G\u00e9n\u00e9tique, Evolution et Contr\u00f4le, Universit\u00e9 Montpellier, Institut de Recherche pour la D\u00e9veloppement, Centre National de la Recherche Scientifique, Montpellier, France;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincent","family":"Legros","sequence":"additional","affiliation":[{"name":"Centre International de Recherche en Infectiologie, Universit\u00e9 de Lyon, Universit\u00e9 Claude Bernard Lyon 1, l\u2019Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale, U1111, Centre National de la Recherche Scientifique, UMR5308 \u00c9cole Normale Sup\u00e9rieure de Lyon, Lyon, France;"},{"name":"Campus V\u00e9t\u00e9rinaire de Lyon, VetAgro Sup, Universit\u00e9 de Lyon, Marcy-l\u2019Etoile, France;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nadine","family":"N\u2019dilimabaka","sequence":"additional","affiliation":[{"name":"D\u00e9partement de Virologie, Unit\u00e9 Emergence des Maladies Virales, Centre Interdisciplinaire de Recherches M\u00e9dicales de Franceville, Franceville, Gabon;"},{"name":"D\u00e9partement de Biologie, Facult\u00e9 des Sciences, Universit\u00e9 des Sciences et Techniques de Masuku, Franceville, Gabon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierre","family":"Becquart","sequence":"additional","affiliation":[{"name":"Maladies Infectieuses et Vecteurs, Ecologie, G\u00e9n\u00e9tique, Evolution et Contr\u00f4le, Universit\u00e9 Montpellier, Institut de Recherche pour la D\u00e9veloppement, Centre National de la Recherche Scientifique, Montpellier, France;"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","container-title":["The American Journal of Tropical Medicine and 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