{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,4]],"date-time":"2025-06-04T06:07:49Z","timestamp":1749017269793},"reference-count":0,"publisher":"American Society of Tropical Medicine and Hygiene","license":[{"start":{"date-parts":[[2024,7,23]],"date-time":"2024-07-23T00:00:00Z","timestamp":1721692800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,7,23]]},"abstract":"<jats:p>Loiasis, a filarial pathogen exclusively endemic in central and western Africa, causes a wide spectrum of symptoms. Understanding the breadth of its clinical manifestations is of importance for adequate patient care and to understand its disease burden. Recurring transient pain in the oral cavity was reported as a self-perceived symptom of loiasis in in-depth interviews of patients in a high transmission region in Gabon. Pain was described as stabbing in character and transient for a few days in its temporal course. A quantitative epidemiological survey indicated that transient tooth pain was experienced by 22% of patients infected with <jats:italic>Loa loa<\/jats:italic>. Among those individuals, it was exclusively reported by patients suffering from migratory loiasis (24%). Similar findings have been previously described for other filarial pathogens, indicating that transient swellings of the periodontium and the soft tissue of the oral cavity may explain this symptom reported by patients with migratory loiasis.<\/jats:p>","DOI":"10.4269\/ajtmh.24-0059","type":"journal-article","created":{"date-parts":[[2024,7,23]],"date-time":"2024-07-23T21:09:42Z","timestamp":1721768982000},"source":"Crossref","is-referenced-by-count":1,"title":["Recurring Transient Tooth Pain as Newly Described Symptom of Migratory Loiasis: A Mixed-Methods Study in Rural Gabon"],"prefix":"10.4269","author":[{"given":"Teite Rebecca","family":"Hildebrandt","sequence":"first","affiliation":[{"name":"Centre de Recherches M\u00e9dicales de Lambar\u00e9n\u00e9, Lambarene, Gabon;"},{"name":"Center for Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine and I. Department of Medicine University Medical Center Hamburg-Eppendorf, Hamburg, Germany;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helmut","family":"Ramharter","sequence":"additional","affiliation":[{"name":"Center for Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine and I. Department of Medicine University Medical Center Hamburg-Eppendorf, Hamburg, Germany;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anita","family":"Lumeka Kabwende","sequence":"additional","affiliation":[{"name":"Centre de Recherches M\u00e9dicales de Lambar\u00e9n\u00e9, Lambarene, Gabon;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lilian","family":"Endamne","sequence":"additional","affiliation":[{"name":"Centre de Recherches M\u00e9dicales de Lambar\u00e9n\u00e9, Lambarene, Gabon;"},{"name":"Center for Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine and I. Department of Medicine University Medical Center Hamburg-Eppendorf, Hamburg, Germany;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saskia D.","family":"Davi","sequence":"additional","affiliation":[{"name":"Centre de Recherches M\u00e9dicales de Lambar\u00e9n\u00e9, Lambarene, Gabon;"},{"name":"Center for Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine and I. Department of Medicine University Medical Center Hamburg-Eppendorf, Hamburg, Germany;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ay\u00f4la Akim","family":"Adegnika","sequence":"additional","affiliation":[{"name":"Centre de Recherches M\u00e9dicales de Lambar\u00e9n\u00e9, Lambarene, Gabon;"},{"name":"Institute for Tropical Medicine, University of T\u00fcbingen, T\u00fcbingen, Germany;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ghyslain","family":"Mombo-Ngoma","sequence":"additional","affiliation":[{"name":"Centre de Recherches M\u00e9dicales de Lambar\u00e9n\u00e9, Lambarene, Gabon;"},{"name":"Center for Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine and I. Department of Medicine University Medical Center Hamburg-Eppendorf, Hamburg, Germany;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Selidji T.","family":"Agnandji","sequence":"additional","affiliation":[{"name":"Centre de Recherches M\u00e9dicales de Lambar\u00e9n\u00e9, Lambarene, Gabon;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johannes","family":"Mischlinger","sequence":"additional","affiliation":[{"name":"Centre de Recherches M\u00e9dicales de Lambar\u00e9n\u00e9, Lambarene, Gabon;"},{"name":"Center for Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine and I. Department of Medicine University Medical Center Hamburg-Eppendorf, Hamburg, Germany;"},{"name":"German Center for Infection Research, Partner Site Hamburg-L\u00fcbeck-Borstel-Riems, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rella","family":"Manego Zoleko","sequence":"additional","affiliation":[{"name":"Centre de Recherches M\u00e9dicales de Lambar\u00e9n\u00e9, Lambarene, Gabon;"},{"name":"Center for Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine and I. Department of Medicine University Medical Center Hamburg-Eppendorf, Hamburg, Germany;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Ramharter","sequence":"additional","affiliation":[{"name":"Centre de Recherches M\u00e9dicales de Lambar\u00e9n\u00e9, Lambarene, Gabon;"},{"name":"Center for Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine and I. 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