{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,8]],"date-time":"2024-08-08T00:14:49Z","timestamp":1723076089484},"reference-count":50,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,8,7]]},"abstract":"ABSTRACT.<\/jats:title>\nPlasmodium<\/jats:italic> and soil-transmitted helminth (STH) coinfection is a major public health problem in developing countries. Its prevalence and associated factors are poorly addressed in the available research. Therefore, this study aimed to assess Plasmodium<\/jats:italic>\u2013STH coinfection prevalence and associated factors among malaria-suspected patients attending Shewa Robit Health Center, north-central Ethiopia. A cross-sectional study was conducted among 379 malaria-suspected patients attending Shewa Robit Health Center from April to May 2023. Stool and blood samples were collected from each participant. Plasmodium<\/jats:italic> and STHs were detected from blood and stool samples by using blood film and the Kato\u2013Katz method, respectively. Data were entered into Epi Info version 7 and analyzed by SPSS version 26. Descriptive statistics were used to compute Plasmodium<\/jats:italic>\u2013STH coinfection. Logistic regression was used to identify associated factors. Variables with a P<\/jats:italic>-value <0.05 were considered statistically significant. Among the study participants, 27.9%, 20.3%, and 13.4% were positive for Plasmodium<\/jats:italic>, STHs, and Plasmodium<\/jats:italic>\u2013STH coinfection, respectively. The prevalence of Plasmodium\u2013Ascaris lumbricoides<\/jats:italic> coinfection was high (7.6%). Unavailability of insecticide-treated bed nets (ITNs), improper use of ITNs, absence of indoor residual spraying, presence of stagnant water, and previous malaria infection were significantly associated (P <<\/jats:italic>0.01) with Plasmodium<\/jats:italic> infection. Being illiterate, using an unimproved latrine, having an untrimmed fingernail, and practicing open defecation were also significantly associated (P <<\/jats:italic>0.03), with STH infection. Being male, illiterate, and living in rural areas were significantly associated (P <<\/jats:italic>0.03) with Plasmodium<\/jats:italic>\u2013STH coinfection. The prevalence of Plasmodium<\/jats:italic>\u2013STH coinfection was high in malaria-endemic areas. Therefore, malaria-suspected cases should be checked for STH infection.<\/jats:p>","DOI":"10.4269\/ajtmh.24-0070","type":"journal-article","created":{"date-parts":[[2024,6,18]],"date-time":"2024-06-18T17:37:22Z","timestamp":1718732242000},"page":"333-340","source":"Crossref","is-referenced-by-count":0,"title":["Prevalence of Plasmodium and Soil-Transmitted Helminth Coinfection and Associated Factors among Malaria-Suspected Patients Attending Shewa Robit Health Center, North-Central Ethiopia"],"prefix":"10.4269","volume":"111","author":[{"given":"Geletaw","family":"Asemahegn","sequence":"first","affiliation":[{"name":"Mehal Meda General Hospital, North Shewa Zone, Amhara National Regional Health Bureau, Ethiopia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tadesse","family":"Hailu","sequence":"additional","affiliation":[{"name":"Department of Medical Laboratory Science, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Animen","family":"Ayehu","sequence":"additional","affiliation":[{"name":"Department of Medical Laboratory Science, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"b1","series-title":"Front Immunol","first-page":"190","article-title":"Current challenges in the identification of pre-erythrocytic malaria vaccine candidate antigens","volume":"11","author":"Bettencourt","year":"2020"},{"key":"b2","series-title":"Mediterr J Hematol Infect Dis","first-page":"e2018004","article-title":"Waldenstr\u00f6m\u2019s macroglobulinemia: An update","volume":"10","author":"Mazzucchelli","year":"2018"},{"key":"b3","series-title":"PLoS Negl Trop Dis","first-page":"e0007201","article-title":"Challenges and opportunities for control and elimination of soil-transmitted helminth infection beyond 2020","volume":"13","author":"Freeman","year":"2019"},{"year":"2023","series-title":"World Malaria Report 2023","key":"b4"},{"year":"2023","series-title":"Soil Transmitted Helminths Infection Report","key":"b5"},{"key":"b6","series-title":"PLoS Negl Trop Dis","first-page":"e0008505","article-title":"The global progress of soil-transmitted helminthiases control in 2020 and World Health Organization targets for 2030","volume":"14","author":"Montresor","year":"2020"},{"key":"b7","series-title":"Parasit Vectors","first-page":"1","article-title":"National mapping of soil-transmitted helminth and schistosome infections in Ethiopia","volume":"13","author":"Leta","year":"2020"},{"key":"b8","series-title":"Open Public Health J","first-page":"284","article-title":"Prevalence, intensity, and factors associated with soil-transmitted helminths infection among children in Zambia: A cross-sectional study","volume":"12","author":"Tembo","year":"2019"},{"key":"b9","series-title":"PLoS Pathog","first-page":"e99","article-title":"Microfluidic modeling of cell\u2212cell interactions in malaria pathogenesis","volume":"3","author":"Antia","year":"2007"},{"year":"2021","series-title":"Examining the Co-Infection Effects of Helminths and Malaria in an Indonesian Community.","author":"Rodr\u00edguez-S\u00e1nchez","key":"b10"},{"key":"b11","series-title":"ASH Education Program Book.","first-page":"87","article-title":"Malaria, erythrocytic infection, and anemia","volume":"2009","author":"Haldar","year":"2009"},{"key":"b12","series-title":"Parasit Vectors","first-page":"1","article-title":"Global numbers of infection and disease burden of soil transmitted helminth infections in 2010","volume":"7","author":"Pullan","year":"2014"},{"key":"b13","series-title":"PLoS Negl Trop Dis","first-page":"e0010321","article-title":"Prevalence and distribution pattern of malaria and soil-transmitted helminth co-endemicity in sub-Saharan Africa, 2000\u20132018: A geospatial analysis","volume":"16","author":"Afolabi","year":"2022"},{"key":"b14","series-title":"Trends Parasitol","first-page":"174","article-title":"Hatching of parasitic nematode eggs: A crucial step determining infection","volume":"38","author":"Mkandawire","year":"2022"},{"key":"b15","series-title":"Trends Parasitol","first-page":"574","article-title":"Soil-transmitted helminthiases: Implications of climate change and human behavior","volume":"26","author":"Weaver","year":"2010"},{"key":"b16","series-title":"Libyan J Med","first-page":"5506","article-title":"Prevalence of intestinal parasitic infections among HIV patients in Benin City, Nigeria","volume":"5","author":"Akinbo","year":"2010"},{"key":"b17","series-title":"Am J Trop Med Hyg","first-page":"540","article-title":"Helminth infection and cognitive impairment among Filipino children","volume":"72","author":"Ezeamama","year":"2005"},{"key":"b18","series-title":"PLoS Negl Trop Dis","first-page":"e0003463","article-title":"Impact of helminth infection during pregnancy on cognitive and motor functions of one-year-old children","volume":"9","author":"Mireku","year":"2015"},{"key":"b19","series-title":"Malar J","first-page":"1","article-title":"Malaria impact on cognitive function of children in a peri-urban community in the Brazilian Amazon","volume":"18","author":"Tapaj\u00f3s","year":"2019"},{"key":"b20","series-title":"J Trop Med","first-page":"1784012","article-title":"Prevalence and associated factors of malaria infection among outpatients visiting Shewa Robit Health Center, northcentral Ethiopia","volume":"2022","author":"Tesfaye","year":"2022"},{"key":"b21","series-title":"BMC Infect Dis","first-page":"1","article-title":"Comorbidity of intestinal helminthiases among malaria outpatients of Wondo Genet Health Centers, southern Ethiopia: Implications for integrated control","volume":"19","author":"Tuasha","year":"2019"},{"year":"2016","series-title":"Recording and Reporting Microscopy Results","key":"b22"},{"year":"1991","series-title":"Basic Laboratory Methods in Medical Parasitology","key":"b23"},{"year":"2002","series-title":"Prevention and Control of Schistosomiasis and Soil-Transmitted Helminthiasis: Report of a WHO expert committee","key":"b24"},{"key":"b25","series-title":"Trends Parasitol","first-page":"547","article-title":"Soil-transmitted helminth infections: Updating the global picture","volume":"19","author":"De Silva","year":"2003"},{"key":"b26","series-title":"BMC Res Notes","first-page":"1","article-title":"Malaria and helminth co-infections in outpatients of Alaba Kulito Health Center, southern Ethiopia: A cross sectional study","volume":"3","author":"Degarege","year":"2010"},{"key":"b27","series-title":"Asian Pac J Trop Med","first-page":"803","article-title":"Malaria helminth co-infections and their contribution for aneamia in febrile patients attending Azzezo Health Center, Gondar, northwest Ethiopia: A cross sectional study","volume":"5","author":"Alemu","year":"2012"},{"key":"b28","series-title":"J Parasitol Vector Biol","first-page":"26","article-title":"Malaria-intestinal helminthes co-infection among patients in Wolkite Health Center and Attat Hospital, Gurage Zone, southern Ethiopia","volume":"10","author":"Teklemariam","year":"2018"},{"key":"b29","series-title":"BMC Infect Dis","first-page":"1","article-title":"Malaria and related outcomes in patients with intestinal helminths: A cross-sectional study","volume":"12","author":"Degarege","year":"2012"},{"key":"b30","series-title":"Parasit Vectors","first-page":"1","article-title":"Epidemiology of co-infection with soil transmitted helminths and Plasmodium falciparum among school children in Bumula District in western Kenya","volume":"8","author":"Kepha","year":"2015"},{"key":"b31","series-title":"Allergy Asthma Clin Immunol","first-page":"1","article-title":"Cytokine profiles among patients co-infected with Plasmodium falciparum malaria and soil borne helminths attending Kampala International University Teaching Hospital, in Uganda","volume":"14","author":"Bwanika","year":"2018"},{"key":"b32","series-title":"Trop Med Int Health","first-page":"409","article-title":"Co\u2010infections with Plasmodium, Ascaris and Giardia among Rwandan schoolchildren","volume":"24","author":"Geus","year":"2019"},{"key":"b33","series-title":"Trop Biomed","first-page":"710","article-title":"Soil-transmitted helminth infections among malaria patients determined by microscopy and real-time PCR methods at two district hospitals in Sarawak, Malaysia","volume":"32","author":"Othman","year":"2015"},{"key":"b34","series-title":"Infect Dis Poverty","first-page":"1","article-title":"Coinfection with malaria and intestinal parasites, and its association with anaemia in children in Cameroon","volume":"4","author":"Njunda","year":"2015"},{"key":"b35","series-title":"J Parasitol Res","first-page":"9573413","article-title":"Synergetic effects of Plasmodium, hookworm, and Schistosoma mansoni infections on hemoglobin level among febrile school age children in Jawe Worda, northwest Ethiopia","volume":"2018","author":"Hailu","year":"2018"},{"key":"b36","series-title":"PLoS One","first-page":"e0154277","article-title":"Magnitude of malaria and factors among febrile cases in low transmission areas of Hadiya zone, Ethiopia: A facility based cross sectional study","volume":"11","author":"Delil","year":"2016"},{"key":"b37","series-title":"PLoS One","first-page":"e0271771","article-title":"Malaria prevalence and risk factors among patients visiting Mizan Tepi University Teaching Hospital, Southwest Ethiopia","volume":"17","author":"Duguma","year":"2022"},{"key":"b38","series-title":"Trop Dis Travel Med Vaccines","first-page":"1","article-title":"Incidence of Plasmodium infections and determinant factors among febrile children in a district of northwest Ethiopia; a cross-sectional study","volume":"4","author":"Hailu","year":"2018"},{"key":"b39","series-title":"Malar J","first-page":"1","article-title":"Malaria prevalence in asymptomatic and symptomatic children in Kiwangwa, Bagamoyo district, Tanzania","volume":"16","author":"Sumari","year":"2017"},{"key":"b40","series-title":"PLoS Negl Trop Dis","first-page":"e0007427","article-title":"Community-level epidemiology of soil-transmitted helminths in the context of school-based deworming: Baseline results of a cluster randomised trial on the coast of Kenya","volume":"13","author":"Halliday","year":"2019"},{"key":"b41","series-title":"PLoS One","first-page":"e0274702","article-title":"Prevalence and intensity of soil-transmitted helminth infections and associated risk factors among household heads living in the peri-urban areas of Jimma town, Oromia, Ethiopia: A community-based cross-sectional study","volume":"17","author":"Zeynudin","year":"2022"},{"key":"b42","series-title":"Trop Med Health","first-page":"1","article-title":"High prevalence of helminths infection and associated risk factors among adults living in a rural setting, central Kenya: A cross-sectional study","volume":"45","author":"Masaku","year":"2017"},{"key":"b43","series-title":"PLoS Negl Trop Dis","first-page":"e1622","article-title":"Improved canine and human visceral leishmaniasis immunodiagnosis using combinations of synthetic peptides in enzyme-linked immunosorbent assay","volume":"6","author":"Costa","year":"2012"},{"key":"b44","series-title":"BioMed Res Int","first-page":"3687873","article-title":"Prevalence and intensity of soil-transmitted helminth infection among rural community of southwest Ethiopia: A community-based study","volume":"2019","author":"Tekalign","year":"2019"},{"key":"b45","series-title":"J Infect Dis Epidemiol.","first-page":"123","article-title":"Risk factors associated with prevalence and intensity of gastrointestinal parasitic infections within households in Tonga Sub-Division, West Region, Cameroon","volume":"6","author":"Igore","year":"2020"},{"key":"b46","series-title":"Parasite Epidemiol Control","first-page":"e00071","article-title":"Epidemiology of soil transmitted helminth infections in the middle-belt of Ghana, Africa","volume":"3","author":"Adu-Gyasi","year":"2018"},{"key":"b47","series-title":"PLoS One","first-page":"e0146214","article-title":"Assessment of current malaria status in light of the ongoing control interventions, socio-demographic and environmental variables in Jiga Area, northwest Ethiopia","volume":"11","author":"Ayalew","year":"2016"},{"key":"b48","series-title":"Malar J","first-page":"1","article-title":"The prevalence of symptomatic and asymptomatic malaria and its associated factors in Debre Elias District communities, northwest Ethiopia","volume":"21","author":"Abebaw","year":"2022"},{"key":"b49","series-title":"BioMed Res Int","first-page":"6553913","article-title":"High prevalence of hookworm species and associated factors among soil-transmitted helminth-infected household contacts in Burie Zuria District, northwest Ethiopia: A community-based cross-sectional study","volume":"2023","author":"Assefa","year":"2023"},{"key":"b50","series-title":"BMC Res Notes","first-page":"1","article-title":"Coinfection of intestinal schistosomiasis and malaria and association with haemoglobin levels and nutritional status in school children in Mara region, Northwestern Tanzania: A cross-sectional exploratory study","volume":"10","author":"Kinung\u2019hi","year":"2017"}],"container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/111\/2\/article-p333.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/111\/2\/article-p333.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/111\/2\/article-p333.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T12:42:02Z","timestamp":1723034522000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/111\/2\/article-p333.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,7]]},"references-count":50,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.24-0070","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"type":"print","value":"0002-9637"},{"type":"electronic","value":"1476-1645"}],"subject":[],"published":{"date-parts":[[2024,8,7]]}}}