{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T23:17:33Z","timestamp":1788304653712,"version":"build-2803163510"},"reference-count":11,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,8,6]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n                  <jats:p>\n                    Human cystic echinococcosis (CE) is caused by the larval forms of\n                    <jats:italic>Echinococcus granulosus<\/jats:italic>\n                    s.l. species complex that mainly affect the liver, with lung as the second most frequent location. We describe our experience with surgical treatment of lung CE, emphasizing the need for the least invasive approach when possible. Patients with intrathoracic CE who accessed our center from January 2019 to November 2023 were reviewed. Twenty-two patients, 12 males (54.5%), mean age 35 years, range 9\u201360, were treated. Eight patients (36.4%) had only lung involvement, seven (31.8%) had both liver and lung involvement, and seven (31.8%) had other locations. Thoracic surgery was required for large dimensions or pain (six each), hemoptysis (four each), skin fistulization and pericardial involvement (two each), and infection and emission of parasitic material by cough (one). A minimally invasive video-assisted thoracic surgery approach was used for 12 (54.5%) patients, whereas 10 underwent anterior thoracotomy. Three patients underwent sequential lung and hepatic surgery in a single session, one with myocardial wall involvement underwent thoracic and cardiac surgery in a single session. All patients received albendazole before and during surgery. There was no operative and postoperative mortality. The mean follow-up was 11.5 months (range 1\u201330). Patients with intrathoracic CE may present with acute and even life-threatening symptoms and should be managed preferably with tissue-sparing surgery by a multidisciplinary team in a referral center.\n                  <\/jats:p>","DOI":"10.4269\/ajtmh.24-0094","type":"journal-article","created":{"date-parts":[[2025,6,17]],"date-time":"2025-06-17T14:25:35Z","timestamp":1750170335000},"page":"298-302","source":"Crossref","is-referenced-by-count":3,"title":["Intrathoracic Echinococcosis: A 5-Year, Single-Center Experience"],"prefix":"10.4269","volume":"113","author":[{"given":"Raffaella","family":"Lissandrin","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases I, IRCCS San Matteo Hospital Foundation, Pavia, Italy;"},{"name":"WHO Collaborating Centre for Clinical Management of Cystic Echinococcosis, University of Pavia, Pavia, Italy;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ambra","family":"Vola","sequence":"additional","affiliation":[{"name":"Microbiology and Virology Unit, IRCCS San Matteo Hospital Foundation, Pavia, Italy;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matilde","family":"Pelizzola","sequence":"additional","affiliation":[{"name":"Department of Clinical, Surgical Diagnostic, and Pediatric Sciences, University of Pavia, Pavia, Italy;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federico","family":"Scopis","sequence":"additional","affiliation":[{"name":"Division of Thoracic Surgery, AOU San Luigi Gonzaga, Torino, Italy;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Meda","sequence":"additional","affiliation":[{"name":"Division of Thoracic Surgery, SS Antonio, Biagio and Cesare Arrigo Hospital, Alessandria, Italy;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristiano","family":"Primiceri","sequence":"additional","affiliation":[{"name":"Division of Thoracic Surgery, SS Antonio, Biagio and Cesare Arrigo Hospital, Alessandria, Italy;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gianluca","family":"D\u2019Alessandro","sequence":"additional","affiliation":[{"name":"Department of Clinical, Surgical Diagnostic, and Pediatric Sciences, University of Pavia, Pavia, Italy;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tommaso","family":"Manciulli","sequence":"additional","affiliation":[{"name":"Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcello","family":"Maestri","sequence":"additional","affiliation":[{"name":"Department of General Surgery 1, IRCCS San Matteo Hospital Foundation, Pavia, Italy;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enrico","family":"Brunetti","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases I, IRCCS San Matteo Hospital Foundation, Pavia, Italy;"},{"name":"WHO Collaborating Centre for Clinical Management of Cystic Echinococcosis, University of Pavia, Pavia, Italy;"},{"name":"Department of Clinical, Surgical Diagnostic, and Pediatric Sciences, University of Pavia, Pavia, Italy;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pietro","family":"Rinaldi","sequence":"additional","affiliation":[{"name":"Division of Thoracic Surgery, SS Antonio, Biagio and Cesare Arrigo Hospital, Alessandria, Italy;"},{"name":"Department of Molecular Medicine, University of Pavia, Pavia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"b1","series-title":"Acta Trop","first-page":"1","article-title":"Expert consensus for the diagnosis and treatment of cystic and alveolar echinococcosis in humans","volume":"114","author":"Brunetti","year":"2010"},{"key":"b2","series-title":"PLoS Negl Trop Dis","first-page":"e1880","article-title":"Diagnosing and staging of cystic echinococcosis: How do CT and MRI perform in comparison to ultrasound?","volume":"6","author":"Stojkovic","year":"2012"},{"key":"b3","series-title":"Curr Opin Infect Dis","first-page":"318","article-title":"Pulmonary cystic echinococcosis","volume":"36","author":"Weber","year":"2023"},{"key":"b4","series-title":"Parasite","first-page":"41","article-title":"International consensus on terminology to be used in the field of echinococcoses","volume":"27","author":"Vuitton","year":"2020"},{"key":"b5","series-title":"Lancet","first-page":"1295","article-title":"Echinococcosis","volume":"362","author":"McManus","year":"2003"},{"key":"b6","series-title":"J Thorac Dis","first-page":"S3446","article-title":"Surgery for parasitic lung infestations: Roles in diagnosis and treatment","volume":"10","author":"Thapa","year":"2018"},{"key":"b7","series-title":"J Laparoendosc Adv Surg Tech A","first-page":"882","article-title":"Video-assisted thoracoscopic surgery to treat hydatid disease of the thorax in adults: Is it feasible?","volume":"22","author":"Findikcioglu","year":"2012"},{"key":"b8","series-title":"Eurasian J Med","first-page":"172","article-title":"Thoracoscopic treatment of pulmonary hydatid cysts may have a high morbidity risk in children: Retrospective analysis","volume":"49","author":"Dokumcu","year":"2017"},{"key":"b9","series-title":"Ann Thorac Surg","first-page":"258","article-title":"Is video-assisted thoracoscopic surgery adequate in treatment of pulmonary hydatidosis?","volume":"100","author":"Alpay","year":"2015"},{"key":"b10","series-title":"Eur J Cardiothorac Surg","first-page":"628","article-title":"Pulmonary hydatidosis: Surgical treatment and follow-up of 240 cases","volume":"16","author":"Burgos","year":"1999"},{"key":"b11","series-title":"Eur Respir J","first-page":"1069","article-title":"Pulmonary echinococcosis","volume":"21","author":"Morar","year":"2003"}],"container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/113\/2\/article-p298.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/113\/2\/article-p298.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/113\/2\/article-p298.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,6]],"date-time":"2025-08-06T14:00:13Z","timestamp":1754488813000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/113\/2\/article-p298.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,6]]},"references-count":11,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.24-0094","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,6]]}}}