{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,3]],"date-time":"2025-04-03T04:13:37Z","timestamp":1743653617178,"version":"3.40.3"},"reference-count":13,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,4,2]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>Neurocysticercosis, a central nervous system infection caused by the zoonotic parasite <jats:italic>Taenia solium<\/jats:italic>, is a leading cause of acquired epilepsy worldwide. It is common in areas with extensive pig farming and pork consumption. This report presents an unusual case of neurocysticercosis in a 28-year-old male from Timor-Leste, a region of nonendemicity for human cases of <jats:italic>Taenia solium<\/jats:italic>. The patient, who had experienced seizures precipitated by headaches, was admitted to the hospital on June 15, 2020. Comprehensive examinations, including neuroimaging, identified multiple cystic lesions suggestive of neurocysticercosis. Initial treatment with praziquantel and prednisolone, as well as levetiracetam, alleviated symptoms. However, symptom recurrence after 5 months prompted additional treatment cycles. This case underscores the importance of increased clinical vigilance in patients from areas of nonendemicity and the challenges in managing neurocysticercosis because of its evolving nature. The global health initiatives aimed at enhancing disease surveillance for human taeniasis are crucial for refining our knowledge on neurocysticercosis.<\/jats:p>","DOI":"10.4269\/ajtmh.24-0205","type":"journal-article","created":{"date-parts":[[2025,1,14]],"date-time":"2025-01-14T16:09:13Z","timestamp":1736870953000},"page":"819-821","source":"Crossref","is-referenced-by-count":0,"title":["A Neurocysticercosis Case from Timor-Leste, A Previously Unidentified Region of Human Taeniasis Endemicity"],"prefix":"10.4269","volume":"112","author":[{"given":"Hanna","family":"Jin","sequence":"first","affiliation":[{"name":"Department of Tropical Medicine & Parasitology, Seoul National University College of Medicine, Seoul, Republic of Korea;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Woojun","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Neurology, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sung Hye","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Environmental Biology & Medical Parasitology, Hanyang University College of Medicine, Seoul, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"b1","series-title":"Trop Parasitol","first-page":"106","article-title":"Neurocysticercosis: A disease of neglect","volume":"3","author":"Mewara","year":"2013"},{"key":"b2","series-title":"Lancet Neurol","first-page":"1202","article-title":"Clinical symptoms, diagnosis, and treatment of neurocysticercosis","volume":"13","author":"Garcia","year":"2014"},{"key":"b3","series-title":"Parasit Vectors","first-page":"613","article-title":"Porcine cysticercosis (Taenia solium and Taenia asiatica): Mapping occurrence and areas potentially at risk in East and Southeast 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(ASTMH)","volume":"66","author":"White","year":"2018"},{"key":"b8","series-title":"Med Res Arch","article-title":"Unraveling the enigma: Navigating challenges in the diagnosis and treatment of neurocysticercosis\u2014A thorough exploration review","volume":"12","author":"Mwang\u2019onde","year":"2024"},{"key":"b9","series-title":"Epilepsia","first-page":"583","article-title":"Epilepsy and neurocysticercosis in Atahualpa: A door-to-door survey in rural coastal Ecuador","volume":"46","author":"Del Brutto","year":"2005"},{"key":"b10","series-title":"Epilepsia","first-page":"1177","article-title":"Reduction in rate of epilepsy from neurocysticercosis by community interventions: The Salama, Honduras study","volume":"52","author":"Medina","year":"2011"},{"key":"b11","series-title":"PLoS Negl Trop Dis","first-page":"e870","article-title":"A systematic review of the frequency of neurocyticercosis with a focus on people with 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