{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T09:57:26Z","timestamp":1782899846487,"version":"3.54.5"},"reference-count":22,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,9,4]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>Bangladesh experienced the largest and deadliest dengue outbreak in 2023, after the virus had reappeared in the country 2 decades earlier. A total of 1,705 people died in Bangladesh, representing the highest case fatality rate (0.5%) due to dengue in the world for that year. The severity of dengue infection is to some extent related to the emergence of new circulating serotypes. To identify the possible predominant serotype in 2023, the reverse transcription polymerase chain reaction-based identification technique was used on stored serum samples of suspected dengue patients during the period between July and December 2023. The overall result of molecular serotyping showed that dengue virus (DENV-2) reappeared as the predominant serotype (74.1%), followed by a moderate number of samples with DENV-1 (19.8%) and DENV-3 (6.1%), in 2023. However, DENV-1 was found to be dominant in a few rural areas of Cox\u2019s Bazar districts. During the 2019 outbreak, DENV-3 was the dominant serotype, which seemed to be replaced by the DENV-2 serotype; this may have impacted the increased case fatality in 2023.<\/jats:p>","DOI":"10.4269\/ajtmh.24-0229","type":"journal-article","created":{"date-parts":[[2024,7,9]],"date-time":"2024-07-09T13:37:39Z","timestamp":1720532259000},"page":"617-621","source":"Crossref","is-referenced-by-count":17,"title":["Resurgence of Dengue Virus Serotype 2: Findings from the 2023 Bangladesh Outbreak"],"prefix":"10.4269","volume":"111","author":[{"given":"Anamul","family":"Hasan","sequence":"first","affiliation":[{"name":"Infectious Diseases Division, International Centre for Diarrheal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Md Fahad","family":"Zamil","sequence":"additional","affiliation":[{"name":"Infectious Diseases Division, International Centre for Diarrheal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Afrida Tabassum","family":"Trina","sequence":"additional","affiliation":[{"name":"Infectious Diseases Division, International Centre for Diarrheal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajat Sanker Roy","family":"Biswas","sequence":"additional","affiliation":[{"name":"Department of Medicine, Chattogram Maa-O-Shishu Hospital Medical College, Chittagong, Bangladesh;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asifa","family":"Kumkum","sequence":"additional","affiliation":[{"name":"Clinical Laboratory Services, Office of Executive Director, International Centre for Diarrheal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dilruba","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Clinical Laboratory Services, Office of Executive Director, International Centre for Diarrheal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad Shafiul","family":"Alam","sequence":"additional","affiliation":[{"name":"Infectious Diseases Division, International Centre for Diarrheal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"b1","series-title":"MMWR Surveill Summ","first-page":"1","article-title":"Epidemiologic trends of dengue in U.S. territories, 2010\u20132020","volume":"72","author":"Ryff","year":"2023"},{"key":"b2","series-title":"Virusdisease","first-page":"303","article-title":"Circulating dengue virus serotypes in Bangladesh from 2013 to 2016","volume":"29","author":"Muraduzzaman","year":"2018"},{"key":"b3","series-title":"Trop Med Infect Dis","first-page":"32","article-title":"Increasing dengue burden and severe dengue risk in Bangladesh: An overview","volume":"8","author":"Kayesh","year":"2023"},{"key":"b4","series-title":"Bull World Health Organ","first-page":"607","article-title":"Improving the built environment in urban areas to control Aedes aegypti-borne diseases","volume":"95","author":"Lindsay","year":"2017"},{"key":"b5","series-title":"PLoS Negl Trop Dis","first-page":"e0005694","article-title":"Increasing airline travel may facilitate co-circulation of multiple dengue virus serotypes in Asia","volume":"11","author":"Tian","year":"2017"},{"key":"b6","series-title":"Nat Commun","first-page":"5439","article-title":"Projecting the future incidence and burden of dengue in Southeast Asia","volume":"14","author":"Col\u00f3n-Gonz\u00e1lez","year":"2023"},{"key":"b7","series-title":"Lancet Infect Dis","first-page":"150","article-title":"Safety and durable immunogenicity of the TV005 tetravalent dengue vaccine, across serotypes and age groups, in dengue-endemic Bangladesh: A randomised, controlled trial","volume":"24","author":"Walsh","year":"2024"},{"key":"b8","series-title":"Pak J Med Res","first-page":"83","article-title":"Dacca fever\u201d \u2013 An outbreak of dengue","volume":"6","author":"Aziz","year":"1967"},{"key":"b9","series-title":"Acta Virol","first-page":"153","article-title":"Serological evidence of dengue fever in the Bangladesh Republic","volume":"24","author":"Gaidamovich","year":"1980"},{"key":"b10","series-title":"Searo-Diagnosis of Dengue Infections by Haemagglutination Inhibition Test (HI) in Suspected Cases in Chittagong, Bangladesh","author":"Amin","year":"1999"},{"key":"b11","series-title":"Emerg Infect Dis","first-page":"1411","article-title":"Serologic evidence of dengue infection before onset of epidemic, Bangladesh","volume":"9","author":"Hossain","year":"2003"},{"key":"b12","series-title":"Southeast Asian J Trop Med Public Health","first-page":"42","article-title":"Predominance of DEN-3 genotype during the recent dengue outbreak in 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