{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T06:52:23Z","timestamp":1778568743449,"version":"3.51.4"},"reference-count":15,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,11,6]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>Leishmaniasis is caused by an obligate intracellular protozoa of the genus <jats:italic>Leishmania<\/jats:italic>. Its clinical manifestations include cutaneous, mucocutaneous, and visceral forms. Sporotrichoid cutaneous leishmaniasis (SCL) is an atypical and rare form of cutaneous leishmaniasis (CL) reported mainly in the Old World. This case report describes SCL in a Japanese man infected with <jats:italic>Leishmania <\/jats:italic>(<jats:italic>Viannia<\/jats:italic>)<jats:italic> peruviana<\/jats:italic> in Peru. His lesions occurred on both feet, with the left foot lesion being a simple CL that resolved spontaneously. However, the lesion on the right foot did not cure by itself; instead, it progressed centrally along the lymph nodes, eventually forming an SCL. Amastigotes were detected in both feet and genetically identified as <jats:italic>L<\/jats:italic>. (<jats:italic>V.<\/jats:italic>) <jats:italic>peruviana<\/jats:italic>. The lesions gradually resolved after treatment with intravenous liposomal amphotericin B. Here, we report the first case of SCL caused by <jats:italic>L<\/jats:italic>. (<jats:italic>V.<\/jats:italic>) <jats:italic>peruviana<\/jats:italic>.<\/jats:p>","DOI":"10.4269\/ajtmh.24-0275","type":"journal-article","created":{"date-parts":[[2024,9,18]],"date-time":"2024-09-18T14:12:09Z","timestamp":1726668729000},"page":"953-955","source":"Crossref","is-referenced-by-count":1,"title":["Case Report: A Case of Sporotrichoid Cutaneous Leishmaniasis Caused by Leishmania (Viannia) peruviana"],"prefix":"10.4269","volume":"111","author":[{"given":"Dai","family":"Akine","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine, Ibaraki Prefectural Central Hospital, Ibaraki Cancer Center, Kasama, Ibaraki, Japan;"},{"name":"Division of Clinical Infectious Diseases, Department of Infection and Immunity, School of Medicine, Jichi Medical University, Shimotsuke, Tochigi, Japan;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teppei","family":"Sasahara","sequence":"additional","affiliation":[{"name":"Division of Clinical Infectious Diseases, Department of Infection and Immunity, School of Medicine, Jichi Medical University, Shimotsuke, Tochigi, Japan;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuka","family":"Hirota","sequence":"additional","affiliation":[{"name":"Department of Pathology, School of Medicine, Jichi Medical University, Shimotsuke, Tochigi, Japan;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirotomo","family":"Kato","sequence":"additional","affiliation":[{"name":"Division of Medical Zoology, Department of Infection and Immunity, School of Medicine, Jichi Medical University, Shimotsuke, Tochigi, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"b1","series-title":"Mandell, Douglas, and Bennett\u2019s Principles and Practice of Infectious Diseases","article-title":"Leishmania species","author":"Aronson","year":"2020"},{"key":"b2","year":"2023"},{"key":"b3","series-title":"Rev Inst Med Trop S\u00e3o Paulo","first-page":"e33","article-title":"Sporotrichoid leishmaniasis: A cross-sectional clinical, epidemiological and laboratory study in Rio de Janeiro State, Brazil Livia","volume":"59","author":"Veloso de Carvalho","year":"2017"},{"key":"b4","series-title":"Clin Dermatol","first-page":"140","article-title":"Cutaneous leishmaniasis: A great imitator","volume":"38","author":"Gurel","year":"2020"},{"key":"b5","series-title":"Trans R Soc Trop Med Hyg","first-page":"552","article-title":"Sporotrichoid cutaneous leishmaniasis due to Leishmania major of different zymodemes in the Sudan and Saudi Arabia: A comparative study","volume":"88","author":"Gaafar","year":"1994"},{"key":"b6","series-title":"PLoS Negl Trop Dis","first-page":"1","article-title":"Natural infections of Pintomyia verrucarum and Pintomyia maranonensis by Leishmania (Viannia) peruviana in the eastern Andes of northern Peru","volume":"15","author":"Kato","year":"2021"},{"key":"b7","series-title":"Int J Dermatol","first-page":"46","article-title":"Cutaneous leishmaniasis: Successful treatment with itraconazole","volume":"45","author":"Consigli","year":"2006"},{"key":"b8","year":"2024"},{"key":"b9","series-title":"Indian J Dermatol Venereol Leprol","first-page":"23","article-title":"Many faces of cutaneous leishmaniasis","volume":"74","author":"Bari","year":"2008"},{"key":"b10","series-title":"Leishmaniasis \u2013 Trends in Epidemiology, Diagnosis and Treatment","article-title":"Sporotrichoid cutaneous leishmaniasis in central Tunisia: Epidemiological and clinical aspects","author":"Ben Sa\u00efd","year":"2014"},{"key":"b11","series-title":"Hum Immunol","first-page":"383","article-title":"Th1\/Th2 immune responses are associated with active cutaneous leishmaniasis and clinical cure is associated with strong interferon-\u03b3 production","volume":"70","author":"Castellano","year":"2009"},{"key":"b12","series-title":"Am J Trop Med Hyg","first-page":"558","article-title":"Disseminated cutaneous leishmaniasis due to Leishmania guyanensis: Case of a patient with 425 lesions","volume":"71","author":"Couppi\u00e9","year":"2004"},{"key":"b13","series-title":"Parasite Immunol","first-page":"423","article-title":"Immunopathogenic competences of Leishmania (V.) braziliensis and L. (L.) amazonensis in American cutaneous leishmaniasis","volume":"31","author":"Silveira","year":"2009"},{"key":"b14","series-title":"Front Cell Infect Microbiol","first-page":"99","article-title":"Leishmania RNA virus: When the host pays the toll","volume":"2","author":"Hartley","year":"2012"},{"key":"b15","series-title":"Science","first-page":"1306","article-title":"Salivary gland lysates from the sand fly Lutzomyia longipalpis enhance Leishmania infectivity","volume":"239","author":"Titus","year":"1988"}],"container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/111\/5\/article-p953.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/111\/5\/article-p953.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/111\/5\/article-p953.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,6]],"date-time":"2024-11-06T13:46:16Z","timestamp":1730900776000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/111\/5\/article-p953.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,6]]},"references-count":15,"journal-issue":{"issue":"5"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.24-0275","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,6]]}}}