{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T21:07:43Z","timestamp":1793308063394,"version":"4.5.0"},"reference-count":0,"publisher":"American Society of Tropical Medicine and Hygiene","license":[{"start":{"date-parts":[[2025,2,11]],"date-time":"2025-02-11T00:00:00Z","timestamp":1739232000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,2,11]]},"abstract":"<jats:p>Zika virus (ZIKV) is a flavivirus transmitted primarily by the bite of infected <jats:italic>Aedes<\/jats:italic> species mosquitoes. Although typically asymptomatic or causing mild symptoms and infrequent neurological disease in older children and adults, infection during pregnancy can result in severe congenital malformations and neurodevelopmental deficits. We conducted a review of published literature and official data sources to describe recent Zika epidemiological trends, building on WHO updates posted in 2019 and 2022. Globally, cases declined after the height of ZIKV transmission in the Americas in 2015\u20132016; however, transmission continues across multiple regions, with intermittent outbreaks reported. As of December 2023, there is documented evidence of current or prior autochthonous mosquito-borne ZIKV transmission in 92 countries and territories; most recently, Guinea, Mali, and Sri Lanka were included on the basis of recent or retrospective testing of specimens collected during surveillance activities or studies. The abundance of asymptomatic and mild infections and limited diagnostic testing suggest that transmission in many locations likely remains underrecognized. Public health authorities, clinicians, communities at risk, and travelers should remain alert to the possibility of ZIKV transmission and implement measures to limit the risk of infection with ZIKV and other <jats:italic>Aedes<\/jats:italic>-borne arboviruses. To strengthen surveillance for ZIKV infections and congenital disease, targeted surveillance using clear case definitions and epidemiologically appropriate laboratory testing algorithms should be applied.<\/jats:p>","DOI":"10.4269\/ajtmh.24-0420","type":"journal-article","created":{"date-parts":[[2025,2,7]],"date-time":"2025-02-07T18:24:03Z","timestamp":1738952643000},"source":"Crossref","is-referenced-by-count":27,"title":["A Review of the Recent Epidemiology of Zika Virus Infection"],"prefix":"10.4269","author":[{"given":"Ingrid B.","family":"Rabe","sequence":"first","affiliation":[{"name":"Department of Epidemic and Pandemic Preparedness and Prevention, World Health Organization, Geneva, Switzerland;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan L.","family":"Hills","sequence":"additional","affiliation":[{"name":"Division of Vector-Borne Diseases, U.S. Centers for Disease Control and Prevention, Fort Collins, Colorado;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joana M.","family":"Haussig","sequence":"additional","affiliation":[{"name":"European Centre for Disease Prevention and Control, Solna, Sweden;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allison T.","family":"Walker","sequence":"additional","affiliation":[{"name":"Divisions of Global Migration Health, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thais","family":"dos Santos","sequence":"additional","affiliation":[{"name":"World Health Organization Regional Office for the Americas\/Pan American Health Organization, Washington, District of Columbia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Luis","family":"San Martin","sequence":"additional","affiliation":[{"name":"World Health Organization Regional Office for the Americas\/Pan American Health Organization, Washington, District of Columbia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gamaliel","family":"Gutierrez","sequence":"additional","affiliation":[{"name":"World Health Organization Regional Office for the Americas\/Pan American Health Organization, Washington, District of Columbia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jairo","family":"Mendez-Rico","sequence":"additional","affiliation":[{"name":"World Health Organization Regional Office for the Americas\/Pan American Health Organization, Washington, District of Columbia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Cruz","family":"Rodriguez","sequence":"additional","affiliation":[{"name":"World Health Organization Regional Office for the Americas\/Pan American Health Organization, Washington, District of Columbia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douglas","family":"Elizondo-Lopez","sequence":"additional","affiliation":[{"name":"World 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Organization Regional Office for the Eastern Mediterranean, Cairo, Egypt;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aya","family":"Yajima","sequence":"additional","affiliation":[{"name":"World Health Organization Regional Office for South-East Asia, New Delhi, India;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manish","family":"Kakkar","sequence":"additional","affiliation":[{"name":"World Health Organization Regional Office for South-East Asia, New Delhi, India;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaya","family":"Kato","sequence":"additional","affiliation":[{"name":"World Health Organization Regional Office for South-East Asia, New Delhi, India;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pushpa R.","family":"Wijesinghe","sequence":"additional","affiliation":[{"name":"World Health Organization Regional Office for South-East Asia, New Delhi, India;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sudath","family":"Samaraweera","sequence":"additional","affiliation":[{"name":"World Health Organization Regional Office for South-East Asia, New Delhi, India;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannah","family":"Brindle","sequence":"additional","affiliation":[{"name":"World Health Organization Regional Office for South-East Asia, New Delhi, India;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hasitha","family":"Tissera","sequence":"additional","affiliation":[{"name":"World Health Organization Regional Office for the Western Pacific, Manila, Philippines;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Kelley","sequence":"additional","affiliation":[{"name":"World Health Organization Regional Office for the Western Pacific, Manila, 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