{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T17:58:17Z","timestamp":1791655097388,"version":"4.3.4"},"reference-count":20,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,4,2]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>The phylogeographic inference approach aims to connect genomic data with epidemiology to understand the spread and evolution of pathogens using visualization of spatiotemporal reconstructions. <jats:italic>Orthohantavirus hantanense<\/jats:italic> (HTNV), the causative agent of hemorrhagic fever with renal syndrome (HFRS), represents a significant global public health concern. Here, we introduce a localized Nextstrain platform for HTNV, offering a comprehensive resource for facilitating spatiotemporal genomic surveillance and the study of evolutionary dynamics of viral genomes. Nextstrain enables web-based visualization and simple sharing of graphic and numeric data through unique web addresses. The Nextstrain build for HTNV stands out for its user-friendly interface and is readily accessible online at <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/nextstrain.org\/community\/KU-MV\/Hantavirus\" xlink:type=\"simple\">https:\/\/nextstrain.org\/community\/KU-MV\/Hantavirus<\/jats:ext-link>. This study provides valuable insights into genomic surveillance, viral phylodynamics, and the evolutionary history of orthohantaviruses for the development of public health policies against endemic HFRS outbreaks.<\/jats:p>","DOI":"10.4269\/ajtmh.24-0432","type":"journal-article","created":{"date-parts":[[2025,1,28]],"date-time":"2025-01-28T17:49:20Z","timestamp":1738086560000},"page":"871-874","source":"Crossref","is-referenced-by-count":3,"title":["Web Visualization for Spatiotemporal Genomic Epidemiology, Annotation, and Mutation Dynamics of Orthohantavirus hantanense Using Nextstrain"],"prefix":"10.4269","volume":"112","author":[{"given":"Kyungmin","family":"Park","sequence":"first","affiliation":[{"name":"Department of Microbiology, Korea University College of Medicine, Seoul, Republic of Korea;"},{"name":"BK21 Graduate Program, Department of Biomedical Sciences, Korea University College of Medicine, Seoul, Republic of Korea;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kijin","family":"Kim","sequence":"additional","affiliation":[{"name":"Centre for Infectious Disease Genomics and One Health, Faculty of Health Sciences, Simon Fraser University, Burnaby, Canada;"},{"name":"Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, Canada;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jongwoo","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Korea University College of Medicine, Seoul, Republic of Korea;"},{"name":"BK21 Graduate Program, Department of Biomedical Sciences, Korea University College of Medicine, Seoul, Republic of Korea;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juyoung","family":"Noh","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Korea University College of Medicine, Seoul, Republic of Korea;"},{"name":"BK21 Graduate Program, Department of Biomedical Sciences, Korea University College of Medicine, Seoul, Republic of Korea;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seong-Gyu","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Korea University College of Medicine, Seoul, Republic of Korea;"},{"name":"BK21 Graduate Program, Department of Biomedical Sciences, Korea University College of Medicine, Seoul, Republic of Korea;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hee-Kyung","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Korea University College of Medicine, Seoul, Republic of Korea;"},{"name":"BK21 Graduate Program, Department of Biomedical Sciences, Korea University College of Medicine, Seoul, Republic of Korea;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ye-rin","family":"Seo","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Korea University College of Medicine, Seoul, Republic of Korea;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin Il","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Korea University College of Medicine, Seoul, Republic of Korea;"},{"name":"BK21 Graduate Program, Department of Biomedical Sciences, Korea University College of Medicine, Seoul, Republic of Korea;"},{"name":"Department of Microbiology, Institute for Viral Diseases, College of Medicine, Korea University, Seoul, Republic of Korea;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Man-Seong","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Korea University College of Medicine, Seoul, Republic of Korea;"},{"name":"BK21 Graduate Program, Department of Biomedical Sciences, Korea University College of Medicine, Seoul, Republic of Korea;"},{"name":"Department of Microbiology, Institute for Viral Diseases, College of Medicine, Korea University, Seoul, Republic of Korea;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Won-Keun","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Microbiology, College of Medicine, Hallym University, Chuncheon, Republic of Korea;"},{"name":"Institute of Medical Research, College of Medicine, Hallym University, Chuncheon, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin-Won","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Korea University College of Medicine, Seoul, Republic of Korea;"},{"name":"BK21 Graduate Program, Department of Biomedical Sciences, Korea University College of Medicine, Seoul, Republic of Korea;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"b1","series-title":"Rev Med Virol","first-page":"35","article-title":"Hantavirus infections in Europe and their impact on public 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