{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,6]],"date-time":"2025-03-06T05:19:51Z","timestamp":1741238391131,"version":"3.38.0"},"reference-count":10,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,3,5]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>Typhoid fever is a human-specific disease caused by subspecies of <jats:italic>Salmonella enterica<\/jats:italic> (<jats:italic>Salmonella<\/jats:italic> Typhi). It spreads through ingestion of contaminated food or water and is diagnosed through blood culture or bone marrow culture. It typically presents as an intestinal infection, with a few patients developing severe disseminated infections. Here, we report a rare case of purulent pericarditis secondary to <jats:italic>S.<\/jats:italic> Typhi infection. A 67-year-old elderly male suffered from recurrent fever, diarrhea, and abdominal pain for 7 days. Initial blood and stool cultures were positive for <jats:italic>Salmonella<\/jats:italic>, and a follow-up blood culture confirmed <jats:italic>S.<\/jats:italic> Typhi. Magnetic resonance imaging showed pericardial abscess and hepatic abscess. After pericardiocentesis, the pericardial fluid culture grew <jats:italic>S.<\/jats:italic> Typhi, confirming the diagnosis of pericardial abscess secondary to <jats:italic>S.<\/jats:italic> Typhi infection. After percutaneous drainage of the pericardial abscess and administration of effective antibiotics, the patient\u2019s symptoms improved significantly. He subsequently recovered and was discharged from the hospital. During follow-up, there were no further recurrences. Disseminated infection secondary to <jats:italic>Salmonella<\/jats:italic> Typhi is extremely rare but can lead to serious life-threatening conditions. Our patient was found to have pericardial abscess caused by <jats:italic>S.<\/jats:italic> Typhi. Effective and adequate antibiotics, along with pericardial abscess drainage, can improve symptoms, assist in diagnosis, and enhance quality of life.<\/jats:p>","DOI":"10.4269\/ajtmh.24-0441","type":"journal-article","created":{"date-parts":[[2024,12,24]],"date-time":"2024-12-24T15:17:01Z","timestamp":1735053421000},"page":"544-547","source":"Crossref","is-referenced-by-count":0,"title":["Pericardial Abscess Due to Salmonella Typhi Infection"],"prefix":"10.4269","volume":"112","author":[{"given":"Manli","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases, The First Affiliated Hospital of Bengbu Medical College, Bengbu, China;"},{"name":"Core Cooperative Unit of National Clinical Research Center for Infectious Diseases, Bengbu, China;"},{"name":"Key Laboratory of Infection and Immunity of Anhui Province, Bengbu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chunming","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, The First Affiliated Hospital of Bengbu Medical College, Bengbu, China;"},{"name":"Core Cooperative Unit of National Clinical Research Center for Infectious Diseases, Bengbu, China;"},{"name":"Key Laboratory of Infection and Immunity of Anhui Province, Bengbu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"b1","series-title":"J Med Case Rep","first-page":"303","article-title":"Ovarian abscess caused by Salmonella enterica serovar Typhi: A case report","volume":"13","author":"Getahun","year":"2019"},{"key":"b2","series-title":"Jpn J Infect Dis","first-page":"166","article-title":"Splenic abscess caused by Salmonella typhi: An uncommon presentation","volume":"74","author":"Kaur","year":"2021"},{"key":"b3","series-title":"J Infect","first-page":"902","article-title":"Complications and mortality of typhoid fever: A global systematic review and meta-analysis","volume":"81","author":"Marchello","year":"2020"},{"key":"b4","series-title":"Malawi Med J","first-page":"159","article-title":"An adolescent with multi-organ involvement from typhoid fever","volume":"31","author":"Kumwenda","year":"2019"},{"key":"b5","series-title":"Lancet","first-page":"1151","article-title":"Global, regional, and national age-sex specific mortality for 264 causes of death, 1980\u20132016: A systematic analysis for the Global Burden of Disease Study 2016","volume":"390","year":"2017"},{"key":"b6","series-title":"mBio","first-page":"e02112-18","article-title":"Salmonella enterica serovar Typhi in Bangladesh: Exploration of genomic diversity and antimicrobial resistance","volume":"9","author":"Tanmoy","year":"2018"},{"key":"b7","series-title":"PLoS One","first-page":"e0164939","article-title":"Typhoid fever in South Africa in an endemic HIV setting","volume":"11","author":"Keddy","year":"2016"},{"key":"b8","series-title":"Zhonghua Nei Ke Za Zhi","first-page":"102","article-title":"Salmonella bacteremia and its disseminated infection should not be neglected","volume":"60","author":"Xue","year":"2021"},{"key":"b9","series-title":"Am J Trop Med Hyg","first-page":"2518","article-title":"A systematic review on antimicrobial resistance among Salmonella Typhi worldwide","volume":"103","author":"Marchello","year":"2020"},{"key":"b10","series-title":"Rev Inst Med Trop Sao Paulo","first-page":"e72","article-title":"The first description of liver abscesses due to Salmonella enterica subsp. enterica in an African HIV-infected young woman: Case report and review of the literature","volume":"63","author":"Talibi Alaoui","year":"2021"}],"container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/112\/3\/article-p544.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/112\/3\/article-p544.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/112\/3\/article-p544.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,5]],"date-time":"2025-03-05T14:31:37Z","timestamp":1741185097000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/112\/3\/article-p544.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,5]]},"references-count":10,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.24-0441","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"type":"print","value":"0002-9637"},{"type":"electronic","value":"1476-1645"}],"subject":[],"published":{"date-parts":[[2025,3,5]]}}}