{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T22:45:12Z","timestamp":1781563512636,"version":"3.54.5"},"reference-count":52,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,4,2]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>Bangladesh is a well-known epidemic zone for dengue fever. Several epidemiological and geographical factors influence the transmission and severity of dengue infection. This study aimed to determine the epidemiological and geographical factors that contributed to the severity of the dengue outbreak in Bangladesh in 2023. This hospital-based cross-sectional study investigated 1,313 dengue patients admitted to public hospitals in Dhaka, Chattogram and Kishoreganj, Bangladesh, between July and December 2023. Multiple logistic regression analyses were conducted to identify the independent risk factors for severe dengue infection. The average age of respondents was 29.5 years, with individuals aged 20\u201340 accounting for 59.5%. Of the 1,313 dengue patients, 19.3% (254) were diagnosed with severe dengue infection. Patients with low monthly income and those lacking awareness of dengue\u2019s spread from clogged rooftop water were respectively 2.35 (adjusted odds ratio [aOR] 2.35; <jats:italic>P<\/jats:italic> &lt;0.05; 95% CI: 1.08\u20135.07) and 2.23 (aOR 2.23; <jats:italic>P<\/jats:italic> &lt;0.05; 95% CI: 1.20\u20134.14) times more likely to develop severe dengue. The dengue outbreak has become a serious public health issue in Bangladesh, with factors such as low family income and lack of awareness contributing to the development of severe cases. These findings provide valuable evidence for policymakers to guide and implement preventive measures and raise awareness.<\/jats:p>","DOI":"10.4269\/ajtmh.24-0477","type":"journal-article","created":{"date-parts":[[2025,2,4]],"date-time":"2025-02-04T16:41:19Z","timestamp":1738687279000},"page":"891-897","source":"Crossref","is-referenced-by-count":2,"title":["Epidemiological and Geographical Factors Associated with Dengue in Bangladesh: A Multicenter Study of the 2023 Dengue Epidemic"],"prefix":"10.4269","volume":"112","author":[{"given":"Abul Faisal Md. Nuruddin","family":"Chowdhury","sequence":"first","affiliation":[{"name":"Department of Medicine, Chittagong Medical College, Chattogram, Bangladesh;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Orindom Shing","family":"Pulock","sequence":"additional","affiliation":[{"name":"Disease Biology and Molecular Epidemiology Research Group, Chattogram, Bangladesh;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Md Abdus","family":"Sattar","sequence":"additional","affiliation":[{"name":"Department of Medicine, Chittagong Medical College, Chattogram, Bangladesh;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noor","family":"Mohammed","sequence":"additional","affiliation":[{"name":"Department of Medicine, Chittagong Medical College, Chattogram, Bangladesh;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arpita","family":"Biswangree","sequence":"additional","affiliation":[{"name":"Disease Biology and Molecular Epidemiology Research Group, Chattogram, Bangladesh;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nishat","family":"Sultana","sequence":"additional","affiliation":[{"name":"Disease Biology and Molecular Epidemiology Research Group, Chattogram, Bangladesh;"},{"name":"Department of Biochemistry & Biotechnology, University of Science and Technology Chittagong, Chattogram, Bangladesh;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masruma Meherine","family":"Prachi","sequence":"additional","affiliation":[{"name":"Department of Medicine, Chittagong Medical College, Chattogram, Bangladesh;"},{"name":"Disease Biology and Molecular Epidemiology Research Group, Chattogram, Bangladesh;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Afsana Yeasmin","family":"Tanzina","sequence":"additional","affiliation":[{"name":"Disease Biology and Molecular Epidemiology Research Group, Chattogram, Bangladesh;"},{"name":"Department of Genetic Engineering & Biotechnology, University of Chittagong, Chattogram, Bangladesh;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meheadi Hasan","family":"Rumi","sequence":"additional","affiliation":[{"name":"Disease Biology and Molecular Epidemiology Research Group, Chattogram, Bangladesh;"},{"name":"Department of Genetic Engineering & Biotechnology, University of Chittagong, Chattogram, Bangladesh;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nazmul","family":"Alam","sequence":"additional","affiliation":[{"name":"Department of Public Health, Asian University for Women, Chattogram, Bangladesh;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H. M. Hamidullah","family":"Mehedi","sequence":"additional","affiliation":[{"name":"Department of Medicine, 250 Bedded General Hospital, Chattogram, Bangladesh;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emrul","family":"Kaiser","sequence":"additional","affiliation":[{"name":"Department of Medicine, Fatikchari Health Complex, Chattogram, Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adnan","family":"Mannan","sequence":"additional","affiliation":[{"name":"Disease Biology and Molecular Epidemiology Research Group, Chattogram, Bangladesh;"},{"name":"Department of Genetic Engineering & Biotechnology, University of Chittagong, Chattogram, Bangladesh;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"b1","series-title":"Postgrad Med J","first-page":"588","article-title":"Dengue viral infections","volume":"80","author":"Malavige","year":"2004"},{"key":"b2","series-title":"Arch Virol","first-page":"1445","article-title":"Secondary infection as a risk factor for dengue hemorrhagic fever\/dengue shock syndrome: An historical perspective and role of antibody-dependent enhancement of infection","volume":"158","author":"Guzman","year":"2013"},{"key":"b3","series-title":"Microbiol Mol Biol Rev","first-page":"281","article-title":"Dengue hemorrhagic fever at 60 years: Early evolution of concepts of causation and treatment","volume":"79","author":"Halstead","year":"2015"},{"key":"b4","series-title":"J Immunol Res","first-page":"6803098","article-title":"Dengue fever: Causes, complications, and vaccine strategies","volume":"2016","author":"Khetarpal","year":"2016"},{"key":"b5"},{"key":"b6","series-title":"PLoS Negl Trop Dis","first-page":"e1760","article-title":"Refining the global spatial limits of dengue virus transmission by evidence-based consensus","volume":"6","author":"Brady","year":"2012"},{"key":"b7","series-title":"Lancet Infect Dis","first-page":"712","article-title":"The global burden of dengue: An analysis from the Global Burden of Disease Study 2013","volume":"16","author":"Stanaway","year":"2016"},{"key":"b8","series-title":"Sci Data","first-page":"140004","article-title":"A global compendium of human dengue virus occurrence","volume":"1","author":"Messina","year":"2014"},{"key":"b9","series-title":"Annu Rev Microbiol","first-page":"71","article-title":"Global spread and persistence of dengue","volume":"62","author":"Kyle","year":"2008"},{"key":"b10"},{"key":"b11"},{"key":"b12","series-title":"Curr Microbiol","first-page":"17","article-title":"Current understanding of the pathogenesis of dengue virus infection","volume":"78","author":"Bhatt","year":"2021"},{"key":"b13","series-title":"BMC Infect. 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