{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T21:32:09Z","timestamp":1775079129261,"version":"3.50.1"},"reference-count":310,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,4,1]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Salmonella enterica<\/jats:italic>\n                    (\n                    <jats:italic>S. enterica<\/jats:italic>\n                    ) is an important pathogen responsible for bloodstream infections, particularly in developing nations. These infections often lead to bacteremia, with a few patients developing cardiac complications in high-risk populations. Myocarditis, a common manifestation, presents with fever, chest pain, and dyspnea and can lead to severe complications, such as cardiogenic shock.\n                    <jats:italic>Salmonella<\/jats:italic>\n                    endocarditis, although rare, predominantly affects the mitral valve and leads to critical complications, including valve perforation and dehiscence, with a high mortality rate. Patients with purulent pericarditis present more acutely with toxic features. Arrhythmias, notably third-degree atrioventricular block and ventricular fibrillation, are prevalent complications primarily due to myocarditis. Diagnostic methods range from isolating\n                    <jats:italic>Salmonella<\/jats:italic>\n                    from clinical samples to immunoblotting and polymerase chain reaction-based assays that target specific genes. Depending on severity, treatment includes supportive care or antibiotic therapy with fluoroquinolones in uncomplicated cases and cephalosporins in complicated cases. Timely diagnosis and appropriate management strategies are crucial for mitigating the morbidity and mortality associated with\n                    <jats:italic>S. enterica<\/jats:italic>\n                    infections.\n                  <\/jats:p>","DOI":"10.4269\/ajtmh.24-0535","type":"journal-article","created":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T15:35:42Z","timestamp":1770737742000},"page":"609-621","source":"Crossref","is-referenced-by-count":0,"title":["Cardiac Complications of Salmonella enterica: A Narrative Review"],"prefix":"10.4269","volume":"114","author":[{"given":"Abul Hasan Shadali","family":"Abdul Khader","sequence":"first","affiliation":[{"name":"Government Kilpauk Medical College, Chennai, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barath Prashanth","family":"Sivasubramanian","sequence":"additional","affiliation":[{"name":"Northeast Georgia Medical Centre, Gainesville, Georgia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nazia","family":"Nagi","sequence":"additional","affiliation":[{"name":"Maulana Azad Medical College, New Delhi, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashwath","family":"Ravisankar","sequence":"additional","affiliation":[{"name":"Thanjavur Medical College, Thanjavur, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ibthisam","family":"Ismail Sharieff","sequence":"additional","affiliation":[{"name":"ESIC Medical College and Hospital, Chennai, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Varshini","family":"Thiruvadi","sequence":"additional","affiliation":[{"name":"Thanjavur Medical College, Thanjavur, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Umabalan","family":"Thirupathy","sequence":"additional","affiliation":[{"name":"Saint Vincent Hospital, Indianapolis, Indiana;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Husna","family":"Qadeer","sequence":"additional","affiliation":[{"name":"ESIC Medical College and Hospital, Chennai, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diviya Bharathi","family":"Ravikumar","sequence":"additional","affiliation":[{"name":"ESIC Medical College and Hospital, Chennai, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siva Naga S.","family":"Yarrarapu","sequence":"additional","affiliation":[{"name":"Monmouth Medical Center, Long Branch, New Jersey;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vikramaditya Samala","family":"Venkata","sequence":"additional","affiliation":[{"name":"Cheshire Medical Center, Keene, New Hampshire;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raghavendra","family":"Tirupathi","sequence":"additional","affiliation":[{"name":"University of Illinois College of Medicine, Peoria, Illinois"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"b1","series-title":"Lancet Infect Dis","first-page":"417","article-title":"Community-acquired bloodstream infections in Africa: A systematic review and meta-analysis","volume":"10","author":"Reddy","year":"2010"},{"key":"b2","series-title":"Lancet Infect Dis","first-page":"480","article-title":"Community-acquired bacterial bloodstream infections in developing countries in south and southeast Asia: A systematic review","volume":"12","author":"Deen","year":"2012"},{"key":"b3","series-title":"Clin Microbiol Rev","first-page":"901","article-title":"Epidemiology, clinical presentation, laboratory diagnosis, antimicrobial resistance, and antimicrobial management of invasive Salmonella infections","volume":"28","author":"Crump","year":"2015"},{"key":"b4","series-title":"Lancet","first-page":"2489","article-title":"Invasive non-typhoidal Salmonella disease: An emerging and neglected tropical disease in Africa","volume":"379","author":"Feasey","year":"2012"},{"key":"b5","series-title":"EClinicalMedicine","first-page":"102883","article-title":"The global burden of enteric fever, 2017-2021: A systematic analysis from the global burden of disease study 2021","volume":"77","author":"Piovani","year":"2024"},{"key":"b6","series-title":"Lancet Infect Dis","first-page":"1312","article-title":"The global burden of non-typhoidal Salmonella invasive disease: A systematic analysis for the Global Burden of Disease Study 2017","volume":"19","year":"2019"},{"key":"b7","series-title":"Clin Infect Dis","first-page":"882","article-title":"International Collaboration on Enteric Disease \u201cBurden of Illness\u201d Studies, 2010. 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