{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,19]],"date-time":"2026-04-19T22:32:47Z","timestamp":1776637967754,"version":"3.51.2"},"reference-count":20,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"1","license":[{"start":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T00:00:00Z","timestamp":1751414400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,7,2]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Escherichia coli<\/jats:italic>\n                    (\n                    <jats:italic>E. coli<\/jats:italic>\n                    ) is a commensal organism in humans and animals. It can serve as a reservoir for antibiotic resistance, thus providing an indicator of drug resistance patterns in a community. We investigated antibiotic resistance in\n                    <jats:italic>E. coli<\/jats:italic>\n                    isolated from nondiarrheal stool samples of 6-month-old infants (\n                    <jats:italic>n<\/jats:italic>\n                    = 110) from northwest Bangladesh. We conducted susceptibility testing using a disc diffusion assay against 20 antibiotics. Resistance was most pronounced for macrolides (98.2% resistant), whereas the most sensitive antibiotics were fosfomycin (100%), gentamicin (99.1%), meropenem (98.2%), mecillinam (97.3%), tigecycline (97.3%), and imipenem (87.3%). Excluding erythromycin, roughly 55% of isolates were multidrug-resistant. Our results likely reflect the burden of drug-resistant\n                    <jats:italic>E. coli<\/jats:italic>\n                    in the guts of infants in rural Bangladesh and the prevailing drug resistance patterns in this community.\n                  <\/jats:p>","DOI":"10.4269\/ajtmh.24-0541","type":"journal-article","created":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T10:44:02Z","timestamp":1747133042000},"page":"134-137","source":"Crossref","is-referenced-by-count":1,"title":["Multidrug-Resistant Escherichia coli Isolated from Stool Samples of Healthy Infants in Rural Bangladeshi Communities"],"prefix":"10.4269","volume":"113","author":[{"given":"Fatema-Tuz","family":"Johura","sequence":"first","affiliation":[{"name":"International Centre for Diarrheal Disease Research, Bangladesh, Dhaka, Bangladesh;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jarin","family":"Tasnim","sequence":"additional","affiliation":[{"name":"International Centre for Diarrheal Disease Research, Bangladesh, Dhaka, Bangladesh;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sahitya Ranjan","family":"Biswas","sequence":"additional","affiliation":[{"name":"International Centre for Diarrheal Disease Research, Bangladesh, Dhaka, Bangladesh;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Riajul","family":"Islam","sequence":"additional","affiliation":[{"name":"International Centre for Diarrheal Disease Research, Bangladesh, Dhaka, Bangladesh;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Talal","family":"Hossain","sequence":"additional","affiliation":[{"name":"International Centre for Diarrheal Disease Research, Bangladesh, Dhaka, Bangladesh;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hafizur","family":"Rahman","sequence":"additional","affiliation":[{"name":"The JiVitA Research Project, Gaibandha, Bangladesh;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saijuddin","family":"Shaikh","sequence":"additional","affiliation":[{"name":"The JiVitA Research Project, Gaibandha, Bangladesh;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hasmot","family":"Ali","sequence":"additional","affiliation":[{"name":"The JiVitA Research Project, Gaibandha, Bangladesh;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Subhra","family":"Chakraborty","sequence":"additional","affiliation":[{"name":"Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alain","family":"Labrique","sequence":"additional","affiliation":[{"name":"Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tahmeed","family":"Ahmed","sequence":"additional","affiliation":[{"name":"International Centre for Diarrheal Disease Research, Bangladesh, Dhaka, Bangladesh;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Md Iqbal","family":"Hossain","sequence":"additional","affiliation":[{"name":"International Centre for Diarrheal Disease Research, Bangladesh, Dhaka, Bangladesh;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Munirul","family":"Alam","sequence":"additional","affiliation":[{"name":"International Centre for Diarrheal Disease Research, Bangladesh, Dhaka, Bangladesh;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda C.","family":"Palmer","sequence":"additional","affiliation":[{"name":"Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"b1","series-title":"Lancet","first-page":"629","article-title":"Global burden of bacterial antimicrobial resistance in 2019: A systematic 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Bangladesh","volume":"17","author":"Rahman","year":"2020"},{"key":"b15","series-title":"Emerg Infect Dis","first-page":"907","article-title":"Multidrug-resistant commensal Escherichia coli in children, Peru and Bolivia","volume":"12","author":"Bartoloni","year":"2006"},{"key":"b16","series-title":"Diagn Microbiol Infect Dis","first-page":"188","article-title":"Community fecal carriage of broad-spectrum cephalosporin-resistant Escherichia coli in Tunisian children","volume":"87","author":"Ferjani","year":"2017"},{"key":"b17","series-title":"Sci Rep","first-page":"22859","article-title":"High prevalence of multiple antibiotic resistance in clinical E. coli isolates from Bangladesh and prediction of molecular resistance determinants using WGS of an XDR isolate","volume":"11","author":"Jain","year":"2021"},{"key":"b18","series-title":"BMC Infect Dis","first-page":"477","article-title":"Antibiotic resistance among Escherichia coli isolates from stool samples of children aged 3 to 14 years 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