{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T12:09:10Z","timestamp":1780142950300,"version":"3.54.0"},"reference-count":16,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,9,3]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p><jats:italic>Elizabethkingia anopheles<\/jats:italic> has recently been recognized as an emerging pathogen linked to neonatal meningitis and bacteremia. In this study, we aimed to evaluate the demographic patterns, clinical presentation, and sensitivity patterns of <jats:italic>Elizabethkingia anophelis<\/jats:italic> (<jats:italic>E. anophelis<\/jats:italic>) isolates at our institution. This retrospective observational study was conducted from 2021 to 2024 at a tertiary care center in Uttar Pradesh. All patients admitted to the intensive care unit who were diagnosed with microbiologically confirmed <jats:italic>E. anophelis<\/jats:italic> infection were included in the study. Samples such as blood, bronchoalveolar lavage fluid, ascitic fluid, endotracheal aspirate, wound pus, and cerebrospinal fluid were sent to the Microbiology laboratory for culture and sensitivity testing. Clinical histories of the patients and details regarding bacterial culture and antibiotic sensitivity results were extracted from the Hospital Information System. A total of 48 inpatients with <jats:italic>E. anophelis<\/jats:italic> infection were included. Most of the patients presented with a diagnosis of bacteremia (<jats:italic>n<\/jats:italic> = 20; 42%), followed by pneumonia (<jats:italic>n<\/jats:italic> = 18; 37.5%). Among the patients with bacteremia (<jats:italic>n<\/jats:italic> = 20), 12 (60%) had a catheter in situ at the time of infection and were diagnosed with catheter-related bloodstream infection. The most common risk factor was diabetes mellitus (52%), followed by endotracheal intubation (43.7%) and hypertension (41.7%). The overall 30-day mortality among patients with <jats:italic>E. anophelis<\/jats:italic> infection was 21%. The increased prevalence and mortality rates among patients with <jats:italic>E. anophelis<\/jats:italic> infection emphasize that timely diagnosis and appropriate treatment can help clinicians reduce mortality in these patients.<\/jats:p>","DOI":"10.4269\/ajtmh.24-0550","type":"journal-article","created":{"date-parts":[[2025,6,10]],"date-time":"2025-06-10T15:28:31Z","timestamp":1749569311000},"page":"678-682","source":"Crossref","is-referenced-by-count":3,"title":["Elizabethkingia anophelis Infection in Intensive Care Unit Patients at a Tertiary Care Center in North India: A Retrospective Study"],"prefix":"10.4269","volume":"113","author":[{"given":"Shailesh","family":"Sengar","sequence":"first","affiliation":[{"name":"Department of Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerlin","family":"Varghese","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashima","family":"Jamwal","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deepika","family":"Sarawat","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nidhi","family":"Tejan","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Surbhi","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sangram Singh","family":"Patel","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chinmoy","family":"Sahu","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"b1","series-title":"J Clin Med","first-page":"1431","article-title":"Risk factors for mortality in patients with Elizabethkingia infection and the clinical impact of the antimicrobial susceptibility patterns of Elizabethkingia species","volume":"9","author":"Seong","year":"2020"},{"key":"b2","series-title":"Infect Drug Resist","first-page":"3257","article-title":"Microbiological characterization and clinical facets of Elizabethkingia bloodstream infections in a tertiary care hospital of eastern India","volume":"16","author":"Sarathi","year":"2023"},{"key":"b3","series-title":"Microorganisms","first-page":"295","article-title":"Elizabethkingia infections in humans: From genomics to clinics","volume":"7","author":"Lin","year":"2019"},{"key":"b4","series-title":"New Microbes New Infect","first-page":"100798","article-title":"Clinical profile, susceptibility patterns, speciation and follow up of infections by Elizabethkingia species: Study on a rare nosocomial pathogen from an intensive care unit of north India","volume":"38","author":"Singh","year":"2020"},{"key":"b5","series-title":"Cureus","first-page":"e32057","article-title":"Elizabethkingia anophelis infections: A case series from a tertiary care hospital in Uttar Pradesh","volume":"14","author":"Singh","year":"2022"},{"key":"b6","series-title":"Sci Rep","first-page":"26045","article-title":"Elizabethkingia anophelis bacteremia is associated with clinically significant infections and high mortality","volume":"6","author":"Lau","year":"2016"},{"key":"b7","series-title":"Indian J Crit Care Med","first-page":"104","article-title":"Elizabethkingia meningoseptica: An emerging nosocomial pathogen causing septicemia in critically ill patients","volume":"23","author":"Sahu","year":"2019"},{"key":"b8","series-title":"Pediatr Infect Dis J","first-page":"e228","article-title":"Elizabethkingia anophelis: An important emerging cause of neonatal sepsis and meningitis in China","volume":"41","author":"Wang","year":"2022"},{"key":"b9","series-title":"Int J Syst Evol Microbiol","first-page":"2670","article-title":"Elizabethkingia anophelis sp. nov., isolated from the midgut of the mosquito Anopheles gambiae","volume":"61","author":"K\u00e4mpfer","year":"2011"},{"key":"b10","series-title":"JMM Case Rep","first-page":"e005163","article-title":"Rare Elizabethkingia anophelis meningitis case in a Danish male","volume":"5","author":"Nielsen","year":"2018"},{"key":"b11","series-title":"Open Forum Infect Dis","first-page":"ofx251","article-title":"Elizabethkingia anophelis: Clinical experience of an academic health system in southeastern Wisconsin","volume":"4","author":"Figueroa Castro","year":"2017"},{"key":"b12","series-title":"Indian J Crit Care Med","first-page":"958","article-title":"Elizabethkingia meningoseptica infections: A case series from a tertiary hospital in South Tamil Nadu","volume":"26","author":"Ganesan","year":"2022"},{"key":"b13","series-title":"CLSI M100: Performance Standards for Antimicrobial Susceptibility Testing","year":"2023"},{"key":"b14","series-title":"Antibiotics (Basel)","first-page":"61","article-title":"A genetic locus in Elizabethkingia anophelis associated with elevated vancomycin resistance and multiple antibiotic reduced susceptibility","volume":"13","author":"Johnson","year":"2024"},{"key":"b15","series-title":"J Clin Microbiol","first-page":"e0254121","article-title":"Antimicrobial susceptibility of Elizabethkingia species: Report from a reference laboratory","volume":"60","author":"Comba","year":"2022"},{"key":"b16","series-title":"Acute Crit Care","first-page":"256","article-title":"Clinical features and outcomes of critically ill patients with Elizabethkingia meningoseptica: An emerging pathogen","volume":"36","author":"Umair","year":"2021"}],"container-title":["The American Journal of Tropical Medicine and 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