{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T12:09:43Z","timestamp":1790683783974,"version":"4.1.0"},"reference-count":11,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,4,2]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>Antitubercular treatment (ATT) is associated with multiple cutaneous adverse drug reactions. Second-line ATT is also associated with numerous adverse reactions; however, cutaneous reactions are under-reported. Oral drug provocation (ODP) in multidrug-resistant tuberculosis is challenging because of the paucity of time and the risk of developing secondary drug resistance in the case of interrupted medication. In this paper, we report a case of drug reaction with eosinophilia and systemic symptoms caused by cycloserine in an 18-year-old girl, which was confirmed with ODP and a patch test.<\/jats:p>","DOI":"10.4269\/ajtmh.24-0557","type":"journal-article","created":{"date-parts":[[2025,1,7]],"date-time":"2025-01-07T14:51:13Z","timestamp":1736261473000},"page":"854-855","source":"Crossref","is-referenced-by-count":1,"title":["Patch Test-Positive Drug Reaction with Eosinophilia and Systemic Symptoms Syndrome Due to Cycloserine in Multidrug-Resistant Tuberculosis: A Case Report with a Review of the Literature"],"prefix":"10.4269","volume":"112","author":[{"given":"Priyadharshini","family":"Basavarajpura Vijay","sequence":"first","affiliation":[{"name":"Department of Dermatology, Maulana Azad Medical College, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mrinal Kanti","family":"Das","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Maulana Azad Medical College, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amar","family":"Bahadur","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Maulana Azad Medical College, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chirantan","family":"Shivaji","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Maulana Azad Medical College, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanvi","family":"Dev","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Maulana Azad Medical College, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"b1","series-title":"Guidelines for Programmatic Management of Drug Resistant Tuberculosis in India","year":"2021"},{"key":"b2","series-title":"Cutis","first-page":"708","article-title":"The International Contact Dermatitis 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Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/112\/4\/article-p854.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/112\/4\/article-p854.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/112\/4\/article-p854.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,2]],"date-time":"2025-04-02T13:31:41Z","timestamp":1743600701000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/112\/4\/article-p854.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,2]]},"references-count":11,"journal-issue":{"issue":"4"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.24-0557","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,2]]}}}