{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,3]],"date-time":"2025-04-03T04:14:35Z","timestamp":1743653675225,"version":"3.40.3"},"reference-count":24,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,4,2]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>Melioidosis is a neglected tropical infection caused by the Gram-negative bacterium <jats:italic>Burkholderia pseudomallei,<\/jats:italic> which is found in soil and water across tropical countries. The infection spectrum ranges from mild localized lesions to severe sepsis. The clinical presentation, severity, and outcome are influenced by the route of infection, bacterial load, strain virulence, and specific virulence genes of <jats:italic>B. pseudomallei<\/jats:italic>. This case series discusses nine melioidosis cases, highlighting the clinical and diagnostic challenges. It underscores the necessity for a high level of clinical suspicion to ensure a timely diagnosis and the prompt initiation of treatment.<\/jats:p>","DOI":"10.4269\/ajtmh.24-0573","type":"journal-article","created":{"date-parts":[[2025,1,14]],"date-time":"2025-01-14T16:09:09Z","timestamp":1736870949000},"page":"849-853","source":"Crossref","is-referenced-by-count":0,"title":["Clinical and Microbiological Profile of Melioidosis in a Tertiary Care Hospital in Kerala, India"],"prefix":"10.4269","volume":"112","author":[{"given":"Divya","family":"Vijayakumar","sequence":"first","affiliation":[{"name":"Department of Microbiology, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hridya","family":"Vikraman","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Poornima","family":"Baby","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dipu","family":"Sathyapalan","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of General Medicine, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amritavarshini","family":"Sreekumar","sequence":"additional","affiliation":[{"name":"Center for Nanoscience and Molecular Medicine, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abitha","family":"Abdulla","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Athira","family":"Santhosh","sequence":"additional","affiliation":[{"name":"Center for Nanoscience and Molecular Medicine, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gautham","family":"Sreekumar","sequence":"additional","affiliation":[{"name":"Center for Nanoscience and Molecular Medicine, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lalitha","family":"Biswas","sequence":"additional","affiliation":[{"name":"Center for Nanoscience and Molecular Medicine, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haritha","family":"Subhagan","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of General Medicine, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chiranjay","family":"Mukhopadhyay","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harpreet","family":"Kaur","sequence":"additional","affiliation":[{"name":"Division of Epidemiology and Communicable Diseases, Indian Council of Medical Research, Department of Health Research, Ministry of Health and Family Welfare, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammed","family":"Ashiq","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raja","family":"Biswas","sequence":"additional","affiliation":[{"name":"Center for Nanoscience and Molecular Medicine, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anil","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"b1","series-title":"Fed Regis","first-page":"61083","article-title":"Possession, use, and transfer of select agents and toxins; biennial review. 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