{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T19:09:35Z","timestamp":1784920175788,"version":"3.55.0"},"reference-count":26,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,8,6]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n                  <jats:p>In the Sahel, malaria transmission is highly dependent on rainfall, and control efforts are conducted during the rainy season. However, because of climate changes, the objectives of this study were to better define the period of transmission in the different ecoclimatic regions and the burden of the disease in young adults, which is poorly investigated. The data from districts in the different ecological zones of Niger were compared. During this study, 26% of all consultations were malaria related, of which 59% were malaria confirmed. This represented 12,000 to 19,000 cases and 12.9 to 25.6 deaths per 100,000 inhabitants. An increase of incidence was seen over the study period but a decline in case fatality rate was also observed. Depending on region, children under 14 years of age (half of the population) accounted for 43\u201380% of cases, which in contrast, underlines a significant malaria burden in young adults, especially in arid regions where transmission is lower. The majority of cases occurred from August to October but appeared later in arid zones. The number of cases positively correlated with the cumulative rainfall over the previous five weeks. However, 17\u201326% of cases were identified during the dry season. This study highlights a high transmission rate that extends throughout the dry season, with \u223c50% of cases registered representing patients &gt;14 years of age, and 25% of cases &gt;25 years. Young adults should thus be considered an at-risk group and should be included in strategies for control.<\/jats:p>","DOI":"10.4269\/ajtmh.24-0613","type":"journal-article","created":{"date-parts":[[2025,5,20]],"date-time":"2025-05-20T10:59:42Z","timestamp":1747738782000},"page":"272-277","source":"Crossref","is-referenced-by-count":1,"title":["Burden of Malaria in Adults in Sahelian Niger: A Retrospective Study (2019\u20132021)"],"prefix":"10.4269","volume":"113","author":[{"given":"Elhadji Yacoudima Y. M.","family":"Aminou","sequence":"first","affiliation":[{"name":"Centre de Recherche M\u00e9dicale et Sanitaire (CERMES), Niamey, Niger;"},{"name":"Direction des Services de Sant\u00e9 et de l\u2019Action Sociale de la Garde Nationale du Niger, Niamey, Niger;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00e9dard","family":"Djedanem","sequence":"additional","affiliation":[{"name":"Centre de Recherche M\u00e9dicale et Sanitaire (CERMES), Niamey, Niger;"},{"name":"EPICENTRE, Niamey, Niger;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lazoumar","family":"Ramatoulaye","sequence":"additional","affiliation":[{"name":"Centre de Recherche M\u00e9dicale et Sanitaire (CERMES), Niamey, Niger;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wazodan","family":"Al Moustapha","sequence":"additional","affiliation":[{"name":"Direction des Services de Sant\u00e9 et de l\u2019Action Sociale de la Garde Nationale du Niger, Niamey, Niger;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Idriss","family":"Hamidou Leyo","sequence":"additional","affiliation":[{"name":"Facult\u00e9 d\u2019Agronomie, Universit\u00e9 Abdou Moumouni de Niamey, Niamey, Niger;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean","family":"Testa","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Nazi Boni, Boni, Burkina Faso;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronan","family":"Jambou","sequence":"additional","affiliation":[{"name":"Centre de Recherche M\u00e9dicale et Sanitaire (CERMES), Niamey, Niger;"},{"name":"Global Health Department, Institut Pasteur France, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"b1","article-title":"Malaria Annual Report 2024.","year":"2024"},{"key":"b2","series-title":"Int J Environ Res Public Health","first-page":"10105","article-title":"Malaria transmission in Sahelian African regions, a witness of climate changes","volume":"19","author":"Jambou","year":"2022"},{"key":"b3","series-title":"PLoS One","first-page":"e0299771","article-title":"A typology of sub-seasonal rainfall evolution during the southern Niger monsoon","volume":"19","author":"Kelley","year":"2024"},{"key":"b4","series-title":"Int J Environ Res Public Health","first-page":"14361","article-title":"Spatio-temporal variability of malaria incidence in the health district of Kati, Mali, 2015\u20132019","volume":"19","author":"Katile","year":"2022"},{"key":"b5","article-title":"Le Paludisme au Niger: Probl\u00e9matique de la Prise en Charge des Cas","author":"Djermakoye-Jackou","year":"2013"},{"key":"b6","series-title":"Med Trop Sante Int","first-page":"mtsibulletin.2021.109","article-title":"Mosquitoes, distribution, and specific richness in eight countries of Africa: Cape Verde, Mauritania, Senegal, Gambia, Mali, Burkina Faso, Niger, and Chad","volume":"1","author":"Ndiaye","year":"2021"},{"key":"b7","series-title":"Bull Soc Path Exo","first-page":"94","article-title":"Eco-\u00e9pid\u00e9miologie du paludisme \u00e0 Niamey et dans la vall\u00e9e du fleuve, R\u00e9publique du Niger, 1992\u20131995","volume":"90","author":"Julvez","year":"1997"},{"key":"b8","series-title":"Ann Soc belge Med trop","first-page":"163","article-title":"Diversit\u00e9 du paludisme en zone sah\u00e9lo-saharienne une revue \u00e0 propos de la situation du Niger, Afrique de l\u2019Ouest","volume":"72","author":"Julvez","year":"1992"},{"key":"b9","series-title":"Malar J","first-page":"38","article-title":"Web-based climate information resources for malaria control in Africa","volume":"5","author":"Grover-Kopec","year":"2006"},{"key":"b10","article-title":"Etude du paludisme chez les adultes dans deux villages du S\u00e9n\u00e9gal: Dielmo et Ndiop","author":"Wotodlo","year":"2010"},{"key":"b11","article-title":"Le paludisme au Mali: Bilan de dix-huit ann\u00e9es d\u2019activit\u00e9s de recherche et de lutte (1985\u20132023)","author":"Saade","year":"2005"},{"key":"b12","series-title":"Int J Bio Chem Sci","first-page":"1995","article-title":"Pr\u00e9valence et facteurs des risques associ\u00e9s au paludisme chez les patients de l\u2019H\u00f4pital Provincial d\u2019 Ab\u00e9ch\u00e9, 1995\u20132004","volume":"13","author":"Doutoum","year":"2019"},{"key":"b13","article-title":"La lutte contre le paludisme en C\u00f4te d\u2019Ivoire: Directives internationales et pratiques m\u00e9dicales (1948\u20131996)","author":"Assani","year":"2017"},{"key":"b14","article-title":"Analyse Spatio-Temporelle des Donn\u00e9es \u00c9pid\u00e9miologiques du Paludisme au Togo. Sant\u00e9 Publique et \u00c9pid\u00e9miologie","author":"Bakai","year":"2021"},{"key":"b15","series-title":"AJTER","first-page":"30","article-title":"Insecticide resistance in Anopheles gambiae sensu lato (Diptera: Culicidae) across different agroecosystems in Niamey, Niger","volume":"3","author":"Mamane Sal\u00e9","year":"2024"},{"key":"b16","series-title":"Malar J","first-page":"385","article-title":"Countrywide insecticide resistance monitoring and first report of the presence of the L1014S knock down resistance in Niger, West Africa","volume":"21","author":"Soumaila","year":"2022"},{"key":"b17","series-title":"Ground Water","first-page":"144","article-title":"Estimate of recharge of a rising water table in semiarid Niger from 3H and 14C modeling","volume":"40","author":"Favreau","year":"2002"},{"key":"b18","series-title":"Nature","first-page":"230","article-title":"Observed controls on resilience of groundwater to climate variability in sub-Saharan Africa","volume":"572","author":"Cuthbert","year":"2019"},{"key":"b19","article-title":"Paludisme grave chez l\u2019adulte dans le service de m\u00e9decine au centre de sant\u00e9 de r\u00e9f\u00e9rence de la commune IV","author":"Dabo","year":"2013"},{"key":"b20","article-title":"Analyse de la Saisonnalit\u00e9 du Paludisme au Togo et D\u00e9tection D\u2019\u00e9pid\u00e9mies Saisonni\u00e8res. Sant\u00e9 Publique et \u00c9pid\u00e9miologie","author":"Thomas","year":"2022"},{"key":"b21","series-title":"Trop Med Infect Dis","first-page":"214","article-title":"Factors influencing second- and third-dose observance during seasonal malaria chemoprevention (SMC): A quantitative study in Burkina Faso, Mali, and Niger","volume":"7","author":"Som\u00e9","year":"2022"},{"key":"b22","article-title":"Variation Spatio-Temporelle des Indicateurs du Paludisme Chez les Enfants de 5 \u00e0 14 ans dans le District Sanitaire de Kangaba, R\u00e9gion de Koulikoro en 2020","author":"Sirama","year":"2023"},{"key":"b23","series-title":"Parasites Hosts Dis","first-page":"455","article-title":"Genetic polymorphism of merozoite surface protein 1 and antifolate-resistant genes in Plasmodium falciparum from Mali and Niger","volume":"61","author":"Lamine","year":"2023"},{"key":"b24","series-title":"Am J Trop Med Hyg","first-page":"1380","article-title":"Comparison of population-based census versus birth history for the estimation of under-5 mortality in Niger","volume":"109","author":"Peterson","year":"2023"},{"key":"b25","series-title":"Trop Med Infect Dis","first-page":"155","article-title":"Prevalence of mutations in the Pfdhfr, Pfdhps, and Pfmdr1 Genes of malarial parasites isolated from symptomatic patients in Dogondoutchi, Niger","volume":"7","author":"Issa","year":"2022"},{"key":"b26","series-title":"Malar J","first-page":"144","article-title":"Therapeutic efficacy and tolerability of artemether-lumefantrine for uncomplicated Plasmodium falciparum malaria in Niger, 2020","volume":"23","author":"Laminou","year":"2024"}],"container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/113\/2\/article-p272.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/113\/2\/article-p272.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/113\/2\/article-p272.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T18:58:20Z","timestamp":1784919500000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/113\/2\/article-p272.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,6]]},"references-count":26,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.24-0613","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,6]]}}}