{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T16:15:18Z","timestamp":1780762518602,"version":"3.54.1"},"reference-count":15,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,7,2]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>Relapsing fever caused by <jats:italic>Borrelia<\/jats:italic> sp. is a neglected disease in Mexico and more studies are needed to update its presence in multiple regions of the country. Here, recombinant proteins glycerophosphodiester phosphodiesterase (GlpQ) and three <jats:italic>Borrelia<\/jats:italic> immunogenic protein A (BipA) variants were used for serosurveillance in 142 human serum samples. Results showed that two persons were positive to <jats:italic>Borrelia<\/jats:italic> extracts and GlpQ but negative to all three BipA, suggesting they were infected by relapsing fever spirochetes of a yet to be determined species. This shows that testing for GlpQ and <jats:italic>Borrelia<\/jats:italic> extracts are a useful tool for potential infections and grants their use in other regions and studies in Mexico.<\/jats:p>","DOI":"10.4269\/ajtmh.24-0636","type":"journal-article","created":{"date-parts":[[2025,4,22]],"date-time":"2025-04-22T17:39:50Z","timestamp":1745343590000},"page":"117-119","source":"Crossref","is-referenced-by-count":1,"title":["Serological Analysis Indicating the Exposure of Two Volunteers to Relapsing Fever Borrelia sp. in Nayarit, Mexico"],"prefix":"10.4269","volume":"113","author":[{"given":"Sof\u00eda L.","family":"Luna-Rojas","sequence":"first","affiliation":[{"name":"Laboratorio de Gen\u00e9tica Microbiana, Departamento de Microbiolog\u00eda, Escuela Nacional de Ciencias Biol\u00f3gicas, Instituto Polit\u00e9cnico Nacional, Mexico City, Mexico;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edwin","family":"V\u00e1zquez-Guerrero","sequence":"additional","affiliation":[{"name":"Laboratorio de Gen\u00e9tica Microbiana, Departamento de Microbiolog\u00eda, Escuela Nacional de Ciencias Biol\u00f3gicas, Instituto Polit\u00e9cnico Nacional, Mexico City, Mexico;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose A.","family":"Hern\u00e1ndez-Mart\u00ednez","sequence":"additional","affiliation":[{"name":"Laboratorio de Gen\u00e9tica Microbiana, Departamento de Microbiolog\u00eda, Escuela Nacional de Ciencias Biol\u00f3gicas, Instituto Polit\u00e9cnico Nacional, Mexico City, Mexico;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeanet","family":"Seraf\u00edn-L\u00f3pez","sequence":"additional","affiliation":[{"name":"Departamento de Inmunolog\u00eda, Escuela Nacional de Ciencias Biol\u00f3gicas, Instituto Polit\u00e9cnico Nacional, Mexico City, Mexico;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando","family":"Mart\u00ednez-Hern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Department of Ecology of Pathogens, General Hospital \u201cDr. Manuel Gea Gonz\u00e1lez\u201d, Mexico City, Mexico;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Alejandro","family":"Martinez-Ibarra","sequence":"additional","affiliation":[{"name":"Laboratorio de Entomolog\u00eda M\u00e9dica, Departamento de Ciencias de la Naturaleza, Centro Universitario del Sur, Universidad de Guadalajara, Guadalajara, Mexico;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rigoberto","family":"Hern\u00e1ndez-Castro","sequence":"additional","affiliation":[{"name":"Department of Ecology of Pathogens, General Hospital \u201cDr. Manuel Gea Gonz\u00e1lez\u201d, Mexico City, Mexico;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Job E.","family":"L\u00f3pez","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, National School of Tropical Medicine, Baylor College of Medicine, Houston, Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. Antonio","family":"Ibarra","sequence":"additional","affiliation":[{"name":"Laboratorio de Gen\u00e9tica Microbiana, Departamento de Microbiolog\u00eda, Escuela Nacional de Ciencias Biol\u00f3gicas, Instituto Polit\u00e9cnico Nacional, Mexico City, Mexico;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"b1","series-title":"PLoS Negl Trop Dis","first-page":"e0007215","article-title":"Case report: A retrospective serological analysis indicating human exposure to tick-borne relapsing fever spirochetes in Sonora, Mexico","volume":"13","author":"V\u00e1zquez-Guerrero","year":"2019"},{"key":"b2","series-title":"Am J Trop Med Hyg","first-page":"510","article-title":"Case report: Exposure to relapsing fever group Borreliae in patients with undifferentiated febrile illness in Mexico","volume":"108","author":"V\u00e1zquez-Guerrero","year":"2023"},{"key":"b3","series-title":"PLoS One","first-page":"e0238496","article-title":"Lyme disease and relapsing 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